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The map label for this gene is lhr [C]

Identifier: 15899206

GI number: 15899206

Start: 2231618

End: 2233765

Strand: Direct

Name: lhr [C]

Synonym: SSO2462

Alternate gene names: 15899206

Gene position: 2231618-2233765 (Clockwise)

Preceding gene: 15899204

Following gene: 15899215

Centisome position: 74.58

GC content: 36.59

Gene sequence:

>2148_bases
ATGAGTTTAGAATTAGAGTGGATGTCAATAGACGACCTAAAATTACCTAGTAACGTTATTGATATAATAAAAAATAGGGG
TATAAAAAAACTTAACCCACCTCAAACTGAAGCGGTAAAAAAAGGTCTATTAGATGGAAATAGACTACTATTGACTTCGC
CTACTGGTTCTGGGAAGACATTAATAGCAGAGATGGGAATAATTTCATTTCTTCTAAAAAACGGAGGAAAAGCAATATAT
GTGACCCCACTTAGGGCTCTTACGAATGAAAAGTATTTAACTTTTAAGGATTGGGAATCAATAGGTTTTAAAGTGGCTAT
GACTTCAGGTGATTATGATACAGATGATGCTTGGTTGAAGAATTATGATATTATAATCACCACTTATGAAAAGTTAGATT
CCCTATGGCGTCATAGACCAGATTGGCTTAATGAGGCTAATTATTTCGTACTGGATGAACTACATTACCTTAACGATCCT
GAAAGAGGGCCAGTAGTTGAGAGCGTCACAATAAGGGCTAAAAGGAGAAATCTATTAGCATTGAGTGCTACAATAAGTAA
CTATAAGCAAATAGCTAAATGGTTAGGAGCAGAACCAGTGGCAACGAATTGGAGACCAGTTCCCCTCATGGAGGGTGTTA
TGTATCCAGAGAGGAAAAAGAAGGAATATACTATACTTTTCAGAGATAATACTGCCAGGAAGGTTCATGGAGATGACGCC
ATAATAGCTTATACTCTAGATAGTCTAAGCAAAAATGGACAAGTTTTAGTTTTTAGGAATTCCAGGAAAATGGCAGAAAG
CACAGCATTAAAGATTGCAAATTACATGAATTTTGTAAGTTTAGATGAGAAAGCCATATCTGAGATTTTAAAACAATTGG
ATGATATCGAGGAAGGTGGAAGTGATGAAAAAGAGTTACTAAAATCTCTTATAAGTAAGGGAGTCGCATATCATCACGCT
GGACTATCAAAGGCGTTAAGGGATATAATAGAGGAGAGTTTCCGGAAAAGAAAAATAAAGGTGATCGTAGCAACTCCAAC
CTTGGCAGCTGGCGTAAATTTACCTGCTAGAACAGTAATAATAGGAGATATTTATCGATTCAATAGGAAGATAGTTGGAT
ATTACGATGAAATTCCAGTTATGGAATATAAGCAAATGAGCGGAAGAGCTGGTAGACCTGGTTTTGATCAGATTGGCGAG
TCAATAATTGTGGTAAGGGATAAGGAAGACGTAGATCGAGTATTTAAGAAATATATACTATCTGATGTTGAACCCATTGA
ATCTAAACTGGGTAGTGAAAGGGCATTTTACACGTTCTTACTTGGCATACTTTCTGCTGAAGGTAGTCTGAGTGAAAAAC
AGCTGGAAGCCTTTGCATATGAATCTCTGCTTGCAAAGTCAGTAGTTGACGTTTATTTTGATAGGGCCATAAGGTGGCTA
TCAGAGCATTCTTTTATCAGAGAGGAAAATAATACGTTTACTTTAACTAATTTTGGAAAGAGGGTTGCTGATCTATATAT
AAATCCATTTACTGCTGACATCATAAGAAAGGGGCTTGAGGGATATAAGGCTTCGTGTGAAATAGCTTACCTCCATTTAC
TAGCGTTTACTCCAGATGGACCATTAGTATCAGTTGGAAGGAATGAGGAAGAAGAGCTAATTGAATTGCTGGAAGACCTA
GAGTGTGAGCTGTTAGTAGAGGAACCTTATGAGGAAGACGAATATTCTCTTTACTTAAATGCGTTAAAAGTGGCGTTGAT
AATGAAGGATTGGATAGATGAAGTTGATGAAGATACCATATTGGGTAAATATAACATAGGTTCTGGAGATTTGAGAAATA
TCGTTGAAACTATGGACTGGTTAACCTATAGTGCTTACCATTTATCTAAAGAGTTAAGGTTAGATGATCACAGCGATAAA
CTTAGGATCTTGAACTTAAGAGTGACTGATGGTGTAAAGGAAGAGCTATTAGAATTAGTTCAAATAGGTGGTGTAGGTAG
GAAGAGAGCTAGATTATTGTACAATAACGGAATTAAAGGACTAGGTGATGTTGTAATGAATCCAGATAGAGTTAGGAACT
TGTTAGGCCAAAAGCTAGGTGAGAGAGTTGTCCAAGAGGCTGCAAGATTACTTAATAGATTTCATTAA

Upstream 100 bases:

>100_bases
TATAACTCTATCTACTACAATGAAAAATTTTCAACGTATTTCTTTACGGAAAATAGGGTGATAGTGCTTAAAAACCTTCT
GCGAGAAGTAAAATAAGTTT

Downstream 100 bases:

>100_bases
TTTGCCAAACGGAGAAATATTCATTGTAAGGGATGAGTGTAATACATTAAAAAGGCTTAGGCTAATCCTTTTAGCCTTGG
GTCAAGAGGTACAACTTAAC

Product: DNA helicase related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MSLELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLIAEMGIISFLLKNGGKAIY
VTPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLKNYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDP
ERGPVVESVTIRAKRRNLLALSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDA
IIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGGSDEKELLKSLISKGVAYHHA
GLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVIIGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGE
SIIVVRDKEDVDRVFKKYILSDVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWL
SEHSFIREENNTFTLTNFGKRVADLYINPFTADIIRKGLEGYKASCEIAYLHLLAFTPDGPLVSVGRNEEEELIELLEDL
ECELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDEDTILGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDHSDK
LRILNLRVTDGVKEELLELVQIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNRFH

Sequences:

>Translated_715_residues
MSLELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLIAEMGIISFLLKNGGKAIY
VTPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLKNYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDP
ERGPVVESVTIRAKRRNLLALSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDA
IIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGGSDEKELLKSLISKGVAYHHA
GLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVIIGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGE
SIIVVRDKEDVDRVFKKYILSDVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWL
SEHSFIREENNTFTLTNFGKRVADLYINPFTADIIRKGLEGYKASCEIAYLHLLAFTPDGPLVSVGRNEEEELIELLEDL
ECELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDEDTILGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDHSDK
LRILNLRVTDGVKEELLELVQIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNRFH
>Mature_714_residues
SLELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLIAEMGIISFLLKNGGKAIYV
TPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLKNYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDPE
RGPVVESVTIRAKRRNLLALSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDAI
IAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGGSDEKELLKSLISKGVAYHHAG
LSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVIIGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGES
IIVVRDKEDVDRVFKKYILSDVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWLS
EHSFIREENNTFTLTNFGKRVADLYINPFTADIIRKGLEGYKASCEIAYLHLLAFTPDGPLVSVGRNEEEELIELLEDLE
CELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDEDTILGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDHSDKL
RILNLRVTDGVKEELLELVQIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNRFH

Specific function: Unknown

COG id: COG1204

COG function: function code R; Superfamily II helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI139394648, Length=769, Percent_Identity=26.1378413524057, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI76880486, Length=466, Percent_Identity=30.9012875536481, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI40217847, Length=430, Percent_Identity=32.093023255814, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI169218225, Length=430, Percent_Identity=32.093023255814, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI110556640, Length=770, Percent_Identity=26.4935064935065, Blast_Score=173, Evalue=6e-43,
Organism=Homo sapiens, GI193211480, Length=467, Percent_Identity=28.051391862955, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI130484567, Length=409, Percent_Identity=29.5843520782396, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI67782311, Length=446, Percent_Identity=26.457399103139, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI222831595, Length=96, Percent_Identity=41.6666666666667, Blast_Score=74, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17537519, Length=454, Percent_Identity=32.5991189427313, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17537127, Length=440, Percent_Identity=30, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI86563272, Length=434, Percent_Identity=29.9539170506912, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17542826, Length=485, Percent_Identity=28.659793814433, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71995032, Length=513, Percent_Identity=30.4093567251462, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71995036, Length=118, Percent_Identity=43.2203389830509, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI133930973, Length=230, Percent_Identity=31.7391304347826, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17552356, Length=209, Percent_Identity=32.5358851674641, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321020, Length=607, Percent_Identity=27.5123558484349, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321710, Length=461, Percent_Identity=31.4533622559653, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322411, Length=500, Percent_Identity=28, Blast_Score=150, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI9755332, Length=503, Percent_Identity=28.2306163021869, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323430, Length=216, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17933644, Length=766, Percent_Identity=25.1958224543081, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24647182, Length=436, Percent_Identity=32.7981651376147, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574898, Length=640, Percent_Identity=27.03125, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24660651, Length=769, Percent_Identity=25.6176853055917, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17864608, Length=475, Percent_Identity=28.8421052631579, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17933658, Length=430, Percent_Identity=27.4418604651163, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR022965
- InterPro:   IPR003583
- InterPro:   IPR014014 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 81390; Mature: 81259

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKT
CCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
LIAEMGIISFLLKNGGKAIYVTPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLK
HHHHHHHHHHHHHCCCCEEEEECHHHHCCCCEEEEECHHHCCEEEEEECCCCCCCCHHHC
NYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDPERGPVVESVTIRAKRRNLLA
CCCEEEEEHHHHHHHHCCCCCHHCCCCEEEEECHHHCCCCCCCCCCHHEEEEEHHCCEEE
LSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDA
EHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCEECCCCE
IIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGG
EEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
SDEKELLKSLISKGVAYHHAGLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCEEEE
IGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGESIIVVRDKEDVDRVFKKYIL
EEHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCCHHHCCCEEEEEECHHHHHHHHHHHHH
SDVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWL
CCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEHSFIREENNTFTLTNFGKRVADLYINPFTADIIRKGLEGYKASCEIAYLHLLAFTPDG
HHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
PLVSVGRNEEEELIELLEDLECELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDEDTI
CEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
LGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDHSDKLRILNLRVTDGVKEELLELV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHH
QIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNRFH
HHCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLELEWMSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKT
CEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
LIAEMGIISFLLKNGGKAIYVTPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLK
HHHHHHHHHHHHHCCCCEEEEECHHHHCCCCEEEEECHHHCCEEEEEECCCCCCCCHHHC
NYDIIITTYEKLDSLWRHRPDWLNEANYFVLDELHYLNDPERGPVVESVTIRAKRRNLLA
CCCEEEEEHHHHHHHHCCCCCHHCCCCEEEEECHHHCCCCCCCCCCHHEEEEEHHCCEEE
LSATISNYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDA
EHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCEECCCCE
IIAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGG
EEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
SDEKELLKSLISKGVAYHHAGLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCEEEE
IGDIYRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGESIIVVRDKEDVDRVFKKYIL
EEHHHHHCCCEEEEECCCCCHHHHHHCCCCCCCCHHHCCCEEEEEECHHHHHHHHHHHHH
SDVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWL
CCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEHSFIREENNTFTLTNFGKRVADLYINPFTADIIRKGLEGYKASCEIAYLHLLAFTPDG
HHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
PLVSVGRNEEEELIELLEDLECELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDEDTI
CEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
LGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDHSDKLRILNLRVTDGVKEELLELV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHH
QIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNRFH
HHCCCCHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]