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The map label for this gene is trxB-3 [H]

Identifier: 15899168

GI number: 15899168

Start: 2196594

End: 2197565

Strand: Direct

Name: trxB-3 [H]

Synonym: SSO2416

Alternate gene names: 15899168

Gene position: 2196594-2197565 (Clockwise)

Preceding gene: 15899165

Following gene: 15899169

Centisome position: 73.41

GC content: 38.17

Gene sequence:

>972_bases
GTGAGTCTTCTACCAAGAACTACAAGTGTAAAACCTGGAGAGAAGTTTGATGTTATAATTGTTGGATTAGGTCCAGCTGC
ATATGGCGCTGCGTTATACAGTGCTAGGTATATGCTAAAGACTTTGGTTATAGGAGAAACTCCAGGTGGGCAGTTAACCG
AAGCTGGTATTGTTGATGACTATCTTGGCTTAATAGAAATTCAAGCAAGTGATATGATAAAAGTGTTTAATAAGCACATA
GAGAAATATGAGGTACCTGTCTTATTGGACATTGTGGAAAAAATTGAAAATAGGGGAGATGAATTTGTAGTAAAAACTAA
GAGAAAGGGTGAGTTTAAAGCTGATAGCGTTATCTTAGGAATAGGAGTAAAGAGAAGAAAGTTAGGTGTACCTGGAGAAC
AAGAATTTGCAGGAAGAGGGATATCATACTGCTCAGTCTGTGATGCACCTCTATTTAAGAACAGAGTCGTTGCGGTTATT
GGAGGAGGAGATTCTGCCTTAGAAGGAGCTGAGATATTATCTAGTTACTCTACTAAAGTCTATTTAATACATAGGAGGGA
CACTTTTAAAGCGCAACCAATCTATGTTGAAACTGTTAAGAAAAAACCAAATGTTGAATTTGTTCTTAATTCAGTAGTGA
AGGAAATTAAGGGAGATAAGGTCGTTAAACAAGTAGTAGTAGAGAATTTGAAAACTGGTGAAATTAAGGAATTGAACGTA
AATGGTGTTTTTATAGAAATAGGATTCGATCCTCCGACAGATTTCGCTAAGAGCAATGGGATAGAAACTGACACAAATGG
ATATATTAAAGTTGATGAGTGGATGAGAACTAGTGTACCGGGAGTGTTTGCTGCAGGAGATTGTACATCAGCGTGGCTGG
GATTTAGGCAAGTCATTACTGCGGTAGCACAAGGTGCAGTAGCTGCGACTTCAGCTTATAGATACGTGACAGAGAAGAAG
GGTAAGAAATGA

Upstream 100 bases:

>100_bases
TACTTTCACACATTTATTCTAGTTTTTACGGTATTTAATTTCACGTTTTTAGAATCGTTGAACAAAACTCTTAAAAATTA
TTTAGTAATATAGTATAGTT

Downstream 100 bases:

>100_bases
TTAATTTATTAAATAAAGTTGCTATAGATGCAACACGATATTTAAATGAAATAAAGAACGAGAAAGATCTAGATAAGGTA
ATTGGGTTTCACGCGGGAGA

Product: thioredoxin reductase (trxB-3)

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVDDYLGLIEIQASDMIKVFNKHI
EKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVI
GGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNV
NGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAATSAYRYVTEKK
GKK

Sequences:

>Translated_323_residues
MSLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVDDYLGLIEIQASDMIKVFNKHI
EKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVI
GGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNV
NGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAATSAYRYVTEKK
GKK
>Mature_322_residues
SLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVDDYLGLIEIQASDMIKVFNKHIE
KYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVIG
GGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNVN
GVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAATSAYRYVTEKKG
KK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226437568, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI65787454, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=36.0128617363344, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=34.2857142857143, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=36.5930599369085, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=34.7133757961783, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35221; Mature: 35090

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVDD
CCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCCHHH
YLGLIEIQASDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILG
HHCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEE
IGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVIGGGDSALEGAEILSSYSTKV
CCCEEEECCCCCCHHHHCCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEE
YLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNV
EEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEC
NGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVIT
CEEEEEECCCCCCCHHHCCCCCCCCCCCEEECCHHHHCCCCEEECCCHHHHHHHHHHHHH
AVAQGAVAATSAYRYVTEKKGKK
HHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVDD
CCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCCHHH
YLGLIEIQASDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILG
HHCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEE
IGVKRRKLGVPGEQEFAGRGISYCSVCDAPLFKNRVVAVIGGGDSALEGAEILSSYSTKV
CCCEEEECCCCCCHHHHCCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEE
YLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNV
EEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEC
NGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVIT
CEEEEEECCCCCCCHHHCCCCCCCCCCCEEECCHHHHCCCCEEECCCHHHHHHHHHHHHH
AVAQGAVAATSAYRYVTEKKGKK
HHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]