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The map label for this gene is eif2B [H]

Identifier: 15899134

GI number: 15899134

Start: 2169053

End: 2169472

Strand: Direct

Name: eif2B [H]

Synonym: SSO2381

Alternate gene names: 15899134

Gene position: 2169053-2169472 (Clockwise)

Preceding gene: 15899128

Following gene: 15899135

Centisome position: 72.49

GC content: 35.48

Gene sequence:

>420_bases
GTGAGTTCAGAAAAAGAATACGTAGAAATGCTTGATAGGCTATACTCGAAATTACCAGAAAAAGGACGTAAGGAAGGTAC
ACAATCATTGCCTAATATGATAATACTCAATATAGGAAATACTACTATAATTAGAAACTTTGCGGAGTATTGTGATAGAA
TTAGAAGAGAGGATAAAATATGTATGAAATACTTGCTAAAGGAACTAGCTGCACCCGGTAACGTAGACGATAAGGGCGAA
CTCGTAATTCAAGGAAAATTCTCCTCGCAAGTAATAAATACCTTAATGGAAAGATTTTTGAAAGCATATGTTGAATGTAG
TACTTGTAAAAGCCTAGACACTATTCTAAAGAAGGAGAAGAAGAGCTGGTATATAGTTTGTCTAGCATGTGGCGCTCAAA
CACCAGTGAAACCACTATGA

Upstream 100 bases:

>100_bases
AAGTATCTGCCCTATTTAGTGCACATCCATATGTCTCAACGTAAATGTTTTTCATTATTCTTCAATAGTATTTTAAACCC
TATTTGCTTATAGGTTTAAT

Downstream 100 bases:

>100_bases
AAGTGCTTTTAAATATAATTAGAGCACAAGGCATGACACTAATAAATATATGTCAAGAGGAATTATTAGGAAAAGTATTC
AGAGAAGGAGAGATAATACT

Product: translation initiation factor IF-2 subunit beta

Products: NA

Alternate protein names: aIF2-beta; eIF-2-beta [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MSSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGE
LVIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEKKSWYIVCLACGAQTPVKPL

Sequences:

>Translated_139_residues
MSSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGE
LVIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEKKSWYIVCLACGAQTPVKPL
>Mature_138_residues
SSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGEL
VIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEKKSWYIVCLACGAQTPVKPL

Specific function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA [H]

COG id: COG1601

COG function: function code J; Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2-beta/eIF-5 family [H]

Homologues:

Organism=Homo sapiens, GI29826335, Length=143, Percent_Identity=30.0699300699301, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508049, Length=98, Percent_Identity=31.6326530612245, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325018, Length=141, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17647377, Length=136, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004458
- InterPro:   IPR002735
- InterPro:   IPR016189
- InterPro:   IPR016190 [H]

Pfam domain/function: PF01873 eIF-5_eIF-2B [H]

EC number: NA

Molecular weight: Translated: 15920; Mature: 15789

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKI
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCHHH
CMKYLLKELAAPGNVDDKGELVIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEK
HHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSWYIVCLACGAQTPVKPL
CCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKI
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCHHH
CMKYLLKELAAPGNVDDKGELVIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEK
HHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSWYIVCLACGAQTPVKPL
CCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA