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The map label for this gene is czcD [H]

Identifier: 15899020

GI number: 15899020

Start: 2061575

End: 2062390

Strand: Direct

Name: czcD [H]

Synonym: SSO2247

Alternate gene names: 15899020

Gene position: 2061575-2062390 (Clockwise)

Preceding gene: 15899019

Following gene: 15899026

Centisome position: 68.9

GC content: 34.44

Gene sequence:

>816_bases
ATGTTAAGAACTTTTGTACTGATGTTTTTCACATCCCTTAGTTTTATTGTAGCTTATTATATTACCTTTAGTCCATTAAT
TTTAGCAGAATTCTCCCACGCTTTGATTGACTTCTTAACAATTGCATTTTCTATTATTGCTATAAAATTCATAGGGGAGA
ATGAAGTAGCTGAGGGGAGATTTTCTTATGGATTACATAGACTAGAAGTTGTTGTTGCTATGATTAATCTCATTATAATT
ATTCTGCTTTCACTTGCCGTGGCATACACTTCTGTAACATCACTGTTTAAGGAAACTACAAATGATTCTTTTACCTTAAT
CGTATCGTCAGCTTTGGCGTCATTTTTAACTTATTTCGCATCCCCTAAAGAAAGGAATGACTTAGGCAAGAAGGGACTAT
ATATGCACATCTTATCAGACTTTCTAGGATATATAATGGGTTTTATCATAGGTATTCTTATCTTTATCTCGGGAATACGT
GAATTAGACCCAGTAGGGGCAATTATACTAGTAATACTGAACTTTGCACTTTCTATTCCGTTATTGAAGGAAGCTTTTTT
AATATTTATGGAAGGCTCATCAGTGAAAATCGACCATATTATGGAAGAACTCACTAAAATTTCCCCTAGCGTTCATCACT
TGCATGTGTGGTCAATTTGCGATCACGTTAAGGTTGCGACACTTCACGTTAAAGTATCTCCAAACTTGACTATAGCCGAG
GCTGATAAAATTAGGGGCTCAATTTGCGATTTTCTTAAAGAAAAATATGGTATCTCTCATGTAACAGTTCAATTTGAGAC
TAACGTTGACGATTAA

Upstream 100 bases:

>100_bases
TAATTACAAACTTTTGTATAAGTCTGGAGCGATCACAGCGTAACCGCTTAGGGTAAACCTTAAAAAGGCTTATTTATAAT
GTTTTTCCATATCTTTACTC

Downstream 100 bases:

>100_bases
TAAAACTGGCTTGGCCACCATTCGATATCTTTGTGAAGTTTACTTCCTACTAGCTTTATTATTTTCTCTCTATCCATTGC
TGAAAACCTAACATCCATGT

Product: cation transport protein (czcD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLRTFVLMFFTSLSFIVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGRFSYGLHRLEVVVAMINLIII
ILLSLAVAYTSVTSLFKETTNDSFTLIVSSALASFLTYFASPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISGIR
ELDPVGAIILVILNFALSIPLLKEAFLIFMEGSSVKIDHIMEELTKISPSVHHLHVWSICDHVKVATLHVKVSPNLTIAE
ADKIRGSICDFLKEKYGISHVTVQFETNVDD

Sequences:

>Translated_271_residues
MLRTFVLMFFTSLSFIVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGRFSYGLHRLEVVVAMINLIII
ILLSLAVAYTSVTSLFKETTNDSFTLIVSSALASFLTYFASPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISGIR
ELDPVGAIILVILNFALSIPLLKEAFLIFMEGSSVKIDHIMEELTKISPSVHHLHVWSICDHVKVATLHVKVSPNLTIAE
ADKIRGSICDFLKEKYGISHVTVQFETNVDD
>Mature_271_residues
MLRTFVLMFFTSLSFIVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGRFSYGLHRLEVVVAMINLIII
ILLSLAVAYTSVTSLFKETTNDSFTLIVSSALASFLTYFASPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISGIR
ELDPVGAIILVILNFALSIPLLKEAFLIFMEGSSVKIDHIMEELTKISPSVHHLHVWSICDHVKVATLHVKVSPNLTIAE
ADKIRGSICDFLKEKYGISHVTVQFETNVDD

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=278, Percent_Identity=19.7841726618705, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786966, Length=262, Percent_Identity=24.8091603053435, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 30277; Mature: 30277

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTFVLMFFTSLSFIVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
FSYGLHRLEVVVAMINLIIIILLSLAVAYTSVTSLFKETTNDSFTLIVSSALASFLTYFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
SPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISGIRELDPVGAIILVILNFALSIP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
LLKEAFLIFMEGSSVKIDHIMEELTKISPSVHHLHVWSICDHVKVATLHVKVSPNLTIAE
HHHHHHEEEECCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEEECCCEEEEH
ADKIRGSICDFLKEKYGISHVTVQFETNVDD
HHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
>Mature Secondary Structure
MLRTFVLMFFTSLSFIVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
FSYGLHRLEVVVAMINLIIIILLSLAVAYTSVTSLFKETTNDSFTLIVSSALASFLTYFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
SPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISGIRELDPVGAIILVILNFALSIP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
LLKEAFLIFMEGSSVKIDHIMEELTKISPSVHHLHVWSICDHVKVATLHVKVSPNLTIAE
HHHHHHEEEECCCCEEHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEEECCCEEEEH
ADKIRGSICDFLKEKYGISHVTVQFETNVDD
HHHHHHHHHHHHHHHHCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA