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The map label for this gene is 15899001

Identifier: 15899001

GI number: 15899001

Start: 2045924

End: 2046595

Strand: Direct

Name: 15899001

Synonym: SSO2226

Alternate gene names: NA

Gene position: 2045924-2046595 (Clockwise)

Preceding gene: 15898997

Following gene: 15899003

Centisome position: 68.37

GC content: 30.36

Gene sequence:

>672_bases
ATGTTAAAATATTCTATGCATTTAAACATCATCTTATTGGAAGCCAGTTTAGAACTAGTTCCTAAAGAAATAGTTAATCA
TCCGGCAGTTATTAAAAACGCCAAGAGGAGGAATAAAAAGCCGGAAGACACATTACTAGACATTTCCTTACACTATCATG
CAATGAAGTATTTAGAAAATAGCCATAAAAGAGGTAGACCGGATATTTTACATCAAGCCTTGCTTGTAATTTTAACAGAT
CCAGTAATTAAAGGTGATATATTTATACATACAATACAATCTAAGATAATTAAGGTAAATCCCAATATGAGGCCACCTAA
AAATTATTTGAGATTTATAGGTTTAATGGAGCAATTATTGAAATACGGTAAAATACCTATTAATGGAGATGAGACTCTAA
TGGAGGTTACAAATCTTACATTAGACAACATTGTGAATAGATATGATTTAATACTATTATCAGAAAAGGGAGAGAAAATT
AATCCAGAAGAAATATGTAAATTAGATGAAAAATGGCTATTAGGAATAGGGGCTTTTCCTCATGGAGATTTTTCTGACAA
AATTTTGAATTTGGCTAAGAAAATTTATTCTATAAGTGGATTTCCTCTGGAAACACAACAGGTTTTATGTAGAATCTTTT
CTGCTTGTAATTCTATTTTAGGTTGGCCTTAG

Upstream 100 bases:

>100_bases
GATTACCACTCTTTGCAGTATTGTAAGCTAGCTCTATAAGCTCGATAATCCTCTTCTTAATCTGGTTTTTTCTTCTCACA
ATAACTAATAAATCCTCTTT

Downstream 100 bases:

>100_bases
CCTTGATAGTAACTATTCCACCTGGTACCACATCCACATCTTGTATCGATAAATCGTACGCCTCTGCGATTTTTGAGAAA
ATTTTTCCAGCACATAAGGT

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLKYSMHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLENSHKRGRPDILHQALLVILTD
PVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLLKYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKI
NPEEICKLDEKWLLGIGAFPHGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP

Sequences:

>Translated_223_residues
MLKYSMHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLENSHKRGRPDILHQALLVILTD
PVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLLKYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKI
NPEEICKLDEKWLLGIGAFPHGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP
>Mature_223_residues
MLKYSMHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLENSHKRGRPDILHQALLVILTD
PVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLLKYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKI
NPEEICKLDEKWLLGIGAFPHGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing [H]

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family [H]

Homologues:

Organism=Homo sapiens, GI194328699, Length=181, Percent_Identity=28.7292817679558, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323215, Length=179, Percent_Identity=31.8435754189944, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639698, Length=208, Percent_Identity=28.3653846153846, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005304 [H]

Pfam domain/function: PF03587 EMG1 [H]

EC number: NA

Molecular weight: Translated: 25557; Mature: 25557

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYSMHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLEN
CEEEEEEEEEEEEECHHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHH
SHKRGRPDILHQALLVILTDPVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLL
HCCCCCHHHHHHHHHHHHCCCCEECHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHH
KYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKINPEEICKLDEKWLLGIGAFP
HHCCCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCHHHHHHHCHHHEEEECCCC
HGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKYSMHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLEN
CEEEEEEEEEEEEECHHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHH
SHKRGRPDILHQALLVILTDPVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLL
HCCCCCHHHHHHHHHHHHCCCCEECHHEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHH
KYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKINPEEICKLDEKWLLGIGAFP
HHCCCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCHHHHHHHCHHHEEEECCCC
HGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]