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The map label for this gene is acd-2 [H]

Identifier: 15898410

GI number: 15898410

Start: 1441519

End: 1443069

Strand: Reverse

Name: acd-2 [H]

Synonym: SSO1597

Alternate gene names: 15898410

Gene position: 1443069-1441519 (Counterclockwise)

Preceding gene: 15898411

Following gene: 15898408

Centisome position: 48.23

GC content: 35.33

Gene sequence:

>1551_bases
TTGGAAATGCAAGAGGGTTTTACCGTATTCTCGCTTCTTAAAAGGGCTGTAACTATGGCGCCAGATAAGGAAATAGTAGA
TCCTTTTCGCAATGTTAGACAGTCATATAAGGAGACTTATGAAAGAATAATAGGTATATCTAACTCAATGTTATCGATTG
GAATATCTAAGGGAAGTATAATAGGGGTTGCAGATTATAACACCCTTAAATTCGTTGAGCTATTATTCGCTTCTAGCTTA
ATAGGTACAATAATATATCCAGTTAATGTCAAACTACCCTACGATCAATTACTTTATACAATTAAACACGCTAGGGTAGA
ATGGTTATTCGCTTCAAAAGATTTCATATTCTTATTTAAGGACTTCACTAAGGAGAAAATTATTAGTATAGATTCCAATG
ATACTAAGATAACTTATGATGATTTGGTAAGTAGAAAACTAGTTAAGGAACCCGAAATTTACGTTAAAGGAAGTGATCCA
TACTCTATCTTATTTACGTCAGGTACAACAGGGTTACCTAAAGCGGTTATGTATACTAATGAAAAAACGGTTCATGGAGC
AATAGGTATGGTGCACCAGCTATCACTTTACAATAGCCCTTCTTCGTTGAAGAACAACGATATCATATTAGGTCTTATAC
CATATTATCATTTATGGTCATGGGGTTCACTATTTCACGCTACTTACCTAGGCGCTAAATACGTCACAAGTGGAAAATTT
GAGCCAATAAAAACATTGGAAATAATAGAAAAGGAAAAGGTAACCTGGCTTAACGCTGTCCCCACAATGATGTATATGTT
ACTAAGCGCAGCCAAACAAGGGCAACTAAATGGCTTAAAAACTTTGATAGGTGGTTCTCCAATATCATCTAATCTGGCTA
AGAAGTTAAAAGAAAGTGGAGTATCTTTTGCATCAATATATGGTGGAACAGATATGTTAGCAATTTCAATTACTATCATT
CCCGCAAATACCAATATACAAAGCATCGAAGATTACGCGAGAGTATATACTCATCCTCTTCCTTTCGTGGAATTGAAAGT
AGTTAAGCCAGACGGTAAAGAGGCTAAAGTAGGAGAGATAGGACATTTATGGGTTAAAACACCTTGGCTACCTGGTGAGT
ATCTTAACGATCTAGAGAATACTAAATCTTCCTACGAGGATGGTTGGTTCAAAACTGGAGATATAGCTATGATTATAGAT
GACTACCATACTATAAGAATCTTGGATAGGGAGAAGGACTTAATAAAGAGTGGAGGAGAGTGGATAATACCTAGTATAAT
TGAGTCAATAATATCTGAAGTAAGTGGAGTAGATCTCGTTGCTGTAATAGGTAGAATAGATGAAAAATGGGGAGAAAGAC
CTATAGCATTAGTCAAAGGTAAGGGATCAAATTTAAAAGAAAACATAATCAGCCATTTAAGAAGTGCTTCAACTCAAGGT
TTGATACCAAAATGGTGGGTTCCAGATGATATAGTTATTGTAGATGATTTACCCCTAACCAGCACTGGAAAGGTTAACAA
AAAAGTTTTAAAAGAGAGAACTAAATGGTGA

Upstream 100 bases:

>100_bases
AGATCTACTATGAGAGATTTCTAATGGGTAGAAGCATTCTACGAGATTATATATCTGAGATACGTGAGCTCATAAATATG
GAAGAGATGAAATAGAGGTT

Downstream 100 bases:

>100_bases
TAATAGGATGTAATTTCATGAAAATACTATAACTTATAAATGGTGGTGAAAAGACGATTTTTGAAAACATCTTTCAGATA
GAAACATCGTACCATCTATA

Product: Acyl-CoA dehydrogenase (acd-2)

Products: NA

Alternate protein names: Medium-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MEMQEGFTVFSLLKRAVTMAPDKEIVDPFRNVRQSYKETYERIIGISNSMLSIGISKGSIIGVADYNTLKFVELLFASSL
IGTIIYPVNVKLPYDQLLYTIKHARVEWLFASKDFIFLFKDFTKEKIISIDSNDTKITYDDLVSRKLVKEPEIYVKGSDP
YSILFTSGTTGLPKAVMYTNEKTVHGAIGMVHQLSLYNSPSSLKNNDIILGLIPYYHLWSWGSLFHATYLGAKYVTSGKF
EPIKTLEIIEKEKVTWLNAVPTMMYMLLSAAKQGQLNGLKTLIGGSPISSNLAKKLKESGVSFASIYGGTDMLAISITII
PANTNIQSIEDYARVYTHPLPFVELKVVKPDGKEAKVGEIGHLWVKTPWLPGEYLNDLENTKSSYEDGWFKTGDIAMIID
DYHTIRILDREKDLIKSGGEWIIPSIIESIISEVSGVDLVAVIGRIDEKWGERPIALVKGKGSNLKENIISHLRSASTQG
LIPKWWVPDDIVIVDDLPLTSTGKVNKKVLKERTKW

Sequences:

>Translated_516_residues
MEMQEGFTVFSLLKRAVTMAPDKEIVDPFRNVRQSYKETYERIIGISNSMLSIGISKGSIIGVADYNTLKFVELLFASSL
IGTIIYPVNVKLPYDQLLYTIKHARVEWLFASKDFIFLFKDFTKEKIISIDSNDTKITYDDLVSRKLVKEPEIYVKGSDP
YSILFTSGTTGLPKAVMYTNEKTVHGAIGMVHQLSLYNSPSSLKNNDIILGLIPYYHLWSWGSLFHATYLGAKYVTSGKF
EPIKTLEIIEKEKVTWLNAVPTMMYMLLSAAKQGQLNGLKTLIGGSPISSNLAKKLKESGVSFASIYGGTDMLAISITII
PANTNIQSIEDYARVYTHPLPFVELKVVKPDGKEAKVGEIGHLWVKTPWLPGEYLNDLENTKSSYEDGWFKTGDIAMIID
DYHTIRILDREKDLIKSGGEWIIPSIIESIISEVSGVDLVAVIGRIDEKWGERPIALVKGKGSNLKENIISHLRSASTQG
LIPKWWVPDDIVIVDDLPLTSTGKVNKKVLKERTKW
>Mature_516_residues
MEMQEGFTVFSLLKRAVTMAPDKEIVDPFRNVRQSYKETYERIIGISNSMLSIGISKGSIIGVADYNTLKFVELLFASSL
IGTIIYPVNVKLPYDQLLYTIKHARVEWLFASKDFIFLFKDFTKEKIISIDSNDTKITYDDLVSRKLVKEPEIYVKGSDP
YSILFTSGTTGLPKAVMYTNEKTVHGAIGMVHQLSLYNSPSSLKNNDIILGLIPYYHLWSWGSLFHATYLGAKYVTSGKF
EPIKTLEIIEKEKVTWLNAVPTMMYMLLSAAKQGQLNGLKTLIGGSPISSNLAKKLKESGVSFASIYGGTDMLAISITII
PANTNIQSIEDYARVYTHPLPFVELKVVKPDGKEAKVGEIGHLWVKTPWLPGEYLNDLENTKSSYEDGWFKTGDIAMIID
DYHTIRILDREKDLIKSGGEWIIPSIIESIISEVSGVDLVAVIGRIDEKWGERPIALVKGKGSNLKENIISHLRSASTQG
LIPKWWVPDDIVIVDDLPLTSTGKVNKKVLKERTKW

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=549, Percent_Identity=25.1366120218579, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI187761345, Length=551, Percent_Identity=25.7713248638838, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI187761343, Length=551, Percent_Identity=25.7713248638838, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI42544132, Length=470, Percent_Identity=22.5531914893617, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI28416953, Length=534, Percent_Identity=22.0973782771536, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI122937307, Length=486, Percent_Identity=21.8106995884774, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI145693145, Length=521, Percent_Identity=23.6084452975048, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI221142682, Length=508, Percent_Identity=24.6062992125984, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788107, Length=358, Percent_Identity=25.1396648044693, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786810, Length=427, Percent_Identity=25.2927400468384, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788595, Length=298, Percent_Identity=25.1677852348993, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786801, Length=451, Percent_Identity=21.2860310421286, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=561, Percent_Identity=26.0249554367201, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71994690, Length=561, Percent_Identity=26.0249554367201, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71994694, Length=561, Percent_Identity=26.0249554367201, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17560308, Length=554, Percent_Identity=25.0902527075812, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17559526, Length=389, Percent_Identity=26.2210796915167, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71996755, Length=487, Percent_Identity=24.6406570841889, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17531443, Length=503, Percent_Identity=25.6461232604374, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17558820, Length=461, Percent_Identity=26.8980477223427, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32563687, Length=467, Percent_Identity=25.2676659528908, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17557194, Length=507, Percent_Identity=23.4714003944773, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538037, Length=516, Percent_Identity=24.2248062015504, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985884, Length=328, Percent_Identity=28.6585365853659, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=451, Percent_Identity=21.7294900221729, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25141359, Length=358, Percent_Identity=22.9050279329609, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355181, Length=518, Percent_Identity=26.4478764478764, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24653035, Length=488, Percent_Identity=26.6393442622951, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24581924, Length=532, Percent_Identity=24.0601503759398, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24648253, Length=483, Percent_Identity=26.2939958592132, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24648255, Length=485, Percent_Identity=26.3917525773196, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI161076582, Length=495, Percent_Identity=26.2626262626263, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21356441, Length=494, Percent_Identity=26.3157894736842, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356947, Length=490, Percent_Identity=25.9183673469388, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648260, Length=494, Percent_Identity=24.6963562753036, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859661, Length=396, Percent_Identity=26.010101010101, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI20130357, Length=452, Percent_Identity=25.2212389380531, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24656500, Length=521, Percent_Identity=22.2648752399232, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21358303, Length=544, Percent_Identity=23.1617647058824, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648257, Length=536, Percent_Identity=23.6940298507463, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922652, Length=496, Percent_Identity=20.9677419354839, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 57859; Mature: 57859

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMQEGFTVFSLLKRAVTMAPDKEIVDPFRNVRQSYKETYERIIGISNSMLSIGISKGSI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
IGVADYNTLKFVELLFASSLIGTIIYPVNVKLPYDQLLYTIKHARVEWLFASKDFIFLFK
EEEECCCHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHEEEEEEECCCEEEEEE
DFTKEKIISIDSNDTKITYDDLVSRKLVKEPEIYVKGSDPYSILFTSGTTGLPKAVMYTN
CCCCCCEEEECCCCCEEEHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEC
EKTVHGAIGMVHQLSLYNSPSSLKNNDIILGLIPYYHLWSWGSLFHATYLGAKYVTSGKF
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHCCCCCC
EPIKTLEIIEKEKVTWLNAVPTMMYMLLSAAKQGQLNGLKTLIGGSPISSNLAKKLKESG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHCC
VSFASIYGGTDMLAISITIIPANTNIQSIEDYARVYTHPLPFVELKVVKPDGKEAKVGEI
CCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
GHLWVKTPWLPGEYLNDLENTKSSYEDGWFKTGDIAMIIDDYHTIRILDREKDLIKSGGE
CEEEEECCCCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCEEEEEEECCHHHHHCCCC
WIIPSIIESIISEVSGVDLVAVIGRIDEKWGERPIALVKGKGSNLKENIISHLRSASTQG
EEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCC
LIPKWWVPDDIVIVDDLPLTSTGKVNKKVLKERTKW
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEMQEGFTVFSLLKRAVTMAPDKEIVDPFRNVRQSYKETYERIIGISNSMLSIGISKGSI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
IGVADYNTLKFVELLFASSLIGTIIYPVNVKLPYDQLLYTIKHARVEWLFASKDFIFLFK
EEEECCCHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHEEEEEEECCCEEEEEE
DFTKEKIISIDSNDTKITYDDLVSRKLVKEPEIYVKGSDPYSILFTSGTTGLPKAVMYTN
CCCCCCEEEECCCCCEEEHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEC
EKTVHGAIGMVHQLSLYNSPSSLKNNDIILGLIPYYHLWSWGSLFHATYLGAKYVTSGKF
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHCCCCCC
EPIKTLEIIEKEKVTWLNAVPTMMYMLLSAAKQGQLNGLKTLIGGSPISSNLAKKLKESG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHCC
VSFASIYGGTDMLAISITIIPANTNIQSIEDYARVYTHPLPFVELKVVKPDGKEAKVGEI
CCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
GHLWVKTPWLPGEYLNDLENTKSSYEDGWFKTGDIAMIIDDYHTIRILDREKDLIKSGGE
CEEEEECCCCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCEEEEEEECCHHHHHCCCC
WIIPSIIESIISEVSGVDLVAVIGRIDEKWGERPIALVKGKGSNLKENIISHLRSASTQG
EEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCC
LIPKWWVPDDIVIVDDLPLTSTGKVNKKVLKERTKW
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1453953 [H]