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The map label for this gene is aspB-3 [H]

Identifier: 15898030

GI number: 15898030

Start: 1018989

End: 1020059

Strand: Direct

Name: aspB-3 [H]

Synonym: SSO1177

Alternate gene names: 15898030

Gene position: 1018989-1020059 (Clockwise)

Preceding gene: 15898028

Following gene: 15898035

Centisome position: 34.05

GC content: 37.25

Gene sequence:

>1071_bases
ATGTACCCAGAATTTTGCCTTGAAAGATGGCAATCCTTAAGGGATTGGAGAGCTAAATACGTCCTTTCAGAAAGTGGAGT
AGAACCATTAGATCTAAGTGAAATCCAAATACCTAACGTTAAGCTAGAGTATGGTCACACAAAGGGACTAATAAAACTAA
GGCAACTAGTATCATCCTTCTATCCCGGGAAGAAAGAGGAAGACGTAATAATAACAGCAGGAGGTGCGGAAGCCAACTAC
GTAACAGTCCTCTCCACAATAGAACCAGGAGATGAAGTAATAGTAGAAATGCCCAATTACATGCAAATCCCCGGATTACT
AAGGGGAATAAACGCCAAGATAAAGTACATTTGGCTAAATGATAACTTTAAGTTAGACTTAAATGAGCTCAACGAAATGG
TTAGTAAGAAAACCAAGGCAATAGTAATAACAAACCCGAATAATCCAACTGGCATGGCACTTTCTGAAAGTGAAATTAAG
GGAATCGTTGATATAGCTGAGGATAATCAAGTGACCATAATAGCTGATGAGGTTTATAGGGGGTCGGAGCATGATGGAAA
TATAAGACCAAGCTTTATTGACTTATACGACAATGCAATAAGTACCAATAGTATGTCAAAGGTTTATGGATTACCGGGGA
TAAGAATAGGGTGGGTTGTGGCAAACAAAGAGTTAGTTGATAAGATGTGGAGTATTAGAGATTACACGTCAATTTCACCC
TCAATTTTAGGGCAAGAAATAGCATATAATGTACTCTTAGAGAAGGAGAAATATATGGATAGGGCGAGGAGAATTGGGTT
AAATAATATAAGGTTATTGGAGAGGTTAATAAGTGATATTGACGTTAAGTGGGTTGAACCTAATGCTACAGTATTAGCTT
ATCTTAAATTGAATGTTAAGAACACTTACGATTTCAGTGCAAGGTTGTTTGAGAAATATAGTGTGTTGGTTAATCCTGGA
GAGTGCTTTGAGATGCCCGGTTATGTCAGGATTGGTTTGGGAAGTACAAATACAGAGTTTTTAAATGAGGCATTATCATT
ATTCATAGGGTATTTAAGGGAGTATGAATAA

Upstream 100 bases:

>100_bases
TCAGCGTTCTTACCTATATCCCTATTCATGAAAACTACATAGCGTTCAAAAGATTAAAAAGCAAGGAACCTTATTAATAC
ATGAAACCCAATATCTCATA

Downstream 100 bases:

>100_bases
AAAGGGGTAGTTTTCAACAATTCCCAAGTAATACGCAAATCAATAATACCCAATAGGTTTCAATAGTTTGGTATAGCCCA
AATGTGGTTAAAAACCTAGG

Product: aspartate aminotransferase (aspB-3)

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MYPEFCLERWQSLRDWRAKYVLSESGVEPLDLSEIQIPNVKLEYGHTKGLIKLRQLVSSFYPGKKEEDVIITAGGAEANY
VTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLNDNFKLDLNELNEMVSKKTKAIVITNPNNPTGMALSESEIK
GIVDIAEDNQVTIIADEVYRGSEHDGNIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISP
SILGQEIAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVKNTYDFSARLFEKYSVLVNPG
ECFEMPGYVRIGLGSTNTEFLNEALSLFIGYLREYE

Sequences:

>Translated_356_residues
MYPEFCLERWQSLRDWRAKYVLSESGVEPLDLSEIQIPNVKLEYGHTKGLIKLRQLVSSFYPGKKEEDVIITAGGAEANY
VTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLNDNFKLDLNELNEMVSKKTKAIVITNPNNPTGMALSESEIK
GIVDIAEDNQVTIIADEVYRGSEHDGNIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISP
SILGQEIAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVKNTYDFSARLFEKYSVLVNPG
ECFEMPGYVRIGLGSTNTEFLNEALSLFIGYLREYE
>Mature_356_residues
MYPEFCLERWQSLRDWRAKYVLSESGVEPLDLSEIQIPNVKLEYGHTKGLIKLRQLVSSFYPGKKEEDVIITAGGAEANY
VTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLNDNFKLDLNELNEMVSKKTKAIVITNPNNPTGMALSESEIK
GIVDIAEDNQVTIIADEVYRGSEHDGNIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISP
SILGQEIAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVKNTYDFSARLFEKYSVLVNPG
ECFEMPGYVRIGLGSTNTEFLNEALSLFIGYLREYE

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=312, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713254, Length=216, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI56713256, Length=216, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI95147551, Length=240, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI169881279, Length=240, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI169881281, Length=145, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=315, Percent_Identity=25.7142857142857, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788627, Length=310, Percent_Identity=26.4516129032258, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786816, Length=228, Percent_Identity=22.3684210526316, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790797, Length=296, Percent_Identity=24.6621621621622, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=185, Percent_Identity=30.2702702702703, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788332, Length=189, Percent_Identity=23.2804232804233, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=322, Percent_Identity=23.9130434782609, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=290, Percent_Identity=27.9310344827586, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=228, Percent_Identity=26.7543859649123, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=228, Percent_Identity=26.7543859649123, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=310, Percent_Identity=25.4838709677419, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18859735, Length=320, Percent_Identity=23.75, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28573069, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646114, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573067, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573065, Length=247, Percent_Identity=25.9109311740891, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356535, Length=203, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 40503; Mature: 40503

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPEFCLERWQSLRDWRAKYVLSESGVEPLDLSEIQIPNVKLEYGHTKGLIKLRQLVSSF
CCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHH
YPGKKEEDVIITAGGAEANYVTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLN
CCCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCEECCHHHHCCCCEEEEEEEC
DNFKLDLNELNEMVSKKTKAIVITNPNNPTGMALSESEIKGIVDIAEDNQVTIIADEVYR
CCCEECHHHHHHHHHCCCCEEEEECCCCCCCCEECHHHCCEEEEECCCCEEEEEEHHHHC
GSEHDGNIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISP
CCCCCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCCCCH
SILGQEIAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCEEEEEEEEECC
NTYDFSARLFEKYSVLVNPGECFEMPGYVRIGLGSTNTEFLNEALSLFIGYLREYE
CCCCHHHHHHHHEEEEECCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPEFCLERWQSLRDWRAKYVLSESGVEPLDLSEIQIPNVKLEYGHTKGLIKLRQLVSSF
CCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHH
YPGKKEEDVIITAGGAEANYVTVLSTIEPGDEVIVEMPNYMQIPGLLRGINAKIKYIWLN
CCCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCEECCHHHHCCCCEEEEEEEC
DNFKLDLNELNEMVSKKTKAIVITNPNNPTGMALSESEIKGIVDIAEDNQVTIIADEVYR
CCCEECHHHHHHHHHCCCCEEEEECCCCCCCCEECHHHCCEEEEECCCCEEEEEEHHHHC
GSEHDGNIRPSFIDLYDNAISTNSMSKVYGLPGIRIGWVVANKELVDKMWSIRDYTSISP
CCCCCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEECHHHHHHHHHHCCCCCCCH
SILGQEIAYNVLLEKEKYMDRARRIGLNNIRLLERLISDIDVKWVEPNATVLAYLKLNVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCEEEEEEEEECC
NTYDFSARLFEKYSVLVNPGECFEMPGYVRIGLGSTNTEFLNEALSLFIGYLREYE
CCCCHHHHHHHHEEEEECCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]