Click here to switch to the map view.

The map label for this gene is 15897978

Identifier: 15897978

GI number: 15897978

Start: 963442

End: 964488

Strand: Direct

Name: 15897978

Synonym: SSO1117

Alternate gene names: NA

Gene position: 963442-964488 (Clockwise)

Preceding gene: 15897977

Following gene: 15897980

Centisome position: 32.2

GC content: 35.34

Gene sequence:

>1047_bases
GTGAAGGTGATGAGATTGACATATCAGAATTCGTTAGGGATCGTTTGGGATCAAAGATTTACTGAAATCTCTTTCTCTCA
CCCCATGATTAGGGATATATCTAAGGCTAGAGTAAGAGATTTCATCAAATTAGCTAAGGAAAAAGTCTCTTTTGTAGAAA
TAAGGCCAGAATACGCTACTAAAGAGGATTTGATGGTTGTTCACACAAGGGATTACATTGGTTTACTCGAAGAGAGCAGT
AAGATTCCCTATATAGGATTTTTAGATCAAGGTGATACTGTTCATTATCCAGGGATGTTTGAAGATATACTACTAGTATT
AGGTTCCTCATTTACTGCCATAAAATATTCTAAATTCTTGGATTACGTCTATATTCCTCTAGGCGGATTTCATCACGCAA
TGCCTAATAGAGCAGTAGGGTTTTGTCCGATAAATGATGTTGCAATAACAGCTCTCAAACTATTAGAGAAGGGTGAAAGG
GTTGCTATTGTGGATGTGGACGCTCATCATGGCAACGGTTTACAATTCATACTATATGATAAACCAATTTTAAAGATAAA
TATTTACGCATATGATGGTAACTTTTTCCCTGGAACTGGGAAGATTGATGAAATAGGCGAGGGGAAGGGTAGGGGGTATA
ACATAAATATTCCTTTACCTTTAGGATCAACGGATGATATTTTTGAGAAAAGTCTAGAAATATTAGACTTATTAGAACTT
TATAATCCTTCTTATGTTCTAGTCGTAGCTGGAGTAGATGGTCATAAAAATGATCAGCTAAAATCCTTAGACCTAACAAC
TAATTCCTATAACCTATTAGGTCTTAGGATAAGAAGAATAAAGAAGACCATAAATTCTAGTATCATTGCTTACGGTGGAG
GGGGATATGGTCCAATGTCGTCCTTAAGTATGGTTTCGTTCTTAGAAGGATTGTTAGGCAGAAGAACTTCTTATGAACCG
CTTACATCTTCTGAGGATATAGGAAAAATAAGAAGAATAGAAAAAATTATTTCAAGATTTAAAACTCTTTCCAACTTCTT
TAGCTAG

Upstream 100 bases:

>100_bases
CTCGTAAATAAACCTATATGTGGTTTTGCGTTTATGGAGATTGTCTTATCTCATAATGGTTATCCTATGATTAGATTCTT
TTTAAACAATGTTAATTTGA

Downstream 100 bases:

>100_bases
TTCAAGCATTAATCCTAAAGCATAACTGACATCTTTATCGCTTGTAGCTCTCAATAAGCCCATAGTTCCGACTGGTCTTG
CGTTTGGTATGTCATTAACC

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKVMRLTYQNSLGIVWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVEIRPEYATKEDLMVVHTRDYIGLLEESS
KIPYIGFLDQGDTVHYPGMFEDILLVLGSSFTAIKYSKFLDYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGER
VAIVDVDAHHGNGLQFILYDKPILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPLPLGSTDDIFEKSLEILDLLEL
YNPSYVLVVAGVDGHKNDQLKSLDLTTNSYNLLGLRIRRIKKTINSSIIAYGGGGYGPMSSLSMVSFLEGLLGRRTSYEP
LTSSEDIGKIRRIEKIISRFKTLSNFFS

Sequences:

>Translated_348_residues
MKVMRLTYQNSLGIVWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVEIRPEYATKEDLMVVHTRDYIGLLEESS
KIPYIGFLDQGDTVHYPGMFEDILLVLGSSFTAIKYSKFLDYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGER
VAIVDVDAHHGNGLQFILYDKPILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPLPLGSTDDIFEKSLEILDLLEL
YNPSYVLVVAGVDGHKNDQLKSLDLTTNSYNLLGLRIRRIKKTINSSIIAYGGGGYGPMSSLSMVSFLEGLLGRRTSYEP
LTSSEDIGKIRRIEKIISRFKTLSNFFS
>Mature_348_residues
MKVMRLTYQNSLGIVWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVEIRPEYATKEDLMVVHTRDYIGLLEESS
KIPYIGFLDQGDTVHYPGMFEDILLVLGSSFTAIKYSKFLDYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGER
VAIVDVDAHHGNGLQFILYDKPILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPLPLGSTDDIFEKSLEILDLLEL
YNPSYVLVVAGVDGHKNDQLKSLDLTTNSYNLLGLRIRRIKKTINSSIIAYGGGGYGPMSSLSMVSFLEGLLGRRTSYEP
LTSSEDIGKIRRIEKIISRFKTLSNFFS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=285, Percent_Identity=30.5263157894737, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13128860, Length=256, Percent_Identity=31.640625, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI8923769, Length=281, Percent_Identity=28.1138790035587, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI293336691, Length=230, Percent_Identity=31.7391304347826, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI262073088, Length=195, Percent_Identity=30.2564102564103, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI262073092, Length=203, Percent_Identity=30.0492610837438, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI148539870, Length=222, Percent_Identity=30.6306306306306, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI169234807, Length=222, Percent_Identity=30.6306306306306, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI30795202, Length=138, Percent_Identity=42.7536231884058, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI30795204, Length=138, Percent_Identity=42.7536231884058, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI17158039, Length=134, Percent_Identity=42.5373134328358, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI153085395, Length=139, Percent_Identity=38.1294964028777, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI13128864, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI20070354, Length=299, Percent_Identity=25.0836120401338, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI62750349, Length=139, Percent_Identity=42.4460431654676, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI62750347, Length=139, Percent_Identity=42.4460431654676, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226529806, Length=221, Percent_Identity=26.6968325791855, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI217272877, Length=290, Percent_Identity=25.1724137931034, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561978, Length=257, Percent_Identity=30.7392996108949, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17508561, Length=254, Percent_Identity=29.5275590551181, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17534739, Length=250, Percent_Identity=30, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI193206283, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540334, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17540332, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193209491, Length=231, Percent_Identity=28.1385281385281, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=302, Percent_Identity=28.1456953642384, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321244, Length=269, Percent_Identity=28.996282527881, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323999, Length=270, Percent_Identity=30, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324307, Length=276, Percent_Identity=28.6231884057971, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325325, Length=194, Percent_Identity=31.9587628865979, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657891, Length=254, Percent_Identity=32.2834645669291, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644244, Length=259, Percent_Identity=30.1158301158301, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641720, Length=181, Percent_Identity=38.121546961326, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360801, Length=181, Percent_Identity=38.121546961326, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360799, Length=181, Percent_Identity=38.121546961326, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360899, Length=281, Percent_Identity=31.6725978647687, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642146, Length=194, Percent_Identity=37.1134020618557, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642144, Length=194, Percent_Identity=37.1134020618557, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642142, Length=194, Percent_Identity=37.1134020618557, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 39187; Mature: 39187

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMRLTYQNSLGIVWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVEIRPEYAT
CCEEEEEECCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
KEDLMVVHTRDYIGLLEESSKIPYIGFLDQGDTVHYPGMFEDILLVLGSSFTAIKYSKFL
CCCEEEEEECHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHHHHHHCCCCCEEEHHHHH
DYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGERVAIVDVDAHHGNGLQFILYD
CEEEEECCCHHHCCCCCCEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEC
KPILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPLPLGSTDDIFEKSLEILDLLEL
CCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
YNPSYVLVVAGVDGHKNDQLKSLDLTTNSYNLLGLRIRRIKKTINSSIIAYGGGGYGPMS
CCCCEEEEEECCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCEEEECCCCCCCHH
SLSMVSFLEGLLGRRTSYEPLTSSEDIGKIRRIEKIISRFKTLSNFFS
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVMRLTYQNSLGIVWDQRFTEISFSHPMIRDISKARVRDFIKLAKEKVSFVEIRPEYAT
CCEEEEEECCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
KEDLMVVHTRDYIGLLEESSKIPYIGFLDQGDTVHYPGMFEDILLVLGSSFTAIKYSKFL
CCCEEEEEECHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHHHHHHCCCCCEEEHHHHH
DYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGERVAIVDVDAHHGNGLQFILYD
CEEEEECCCHHHCCCCCCEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEC
KPILKINIYAYDGNFFPGTGKIDEIGEGKGRGYNINIPLPLGSTDDIFEKSLEILDLLEL
CCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
YNPSYVLVVAGVDGHKNDQLKSLDLTTNSYNLLGLRIRRIKKTINSSIIAYGGGGYGPMS
CCCCEEEEEECCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCEEEECCCCCCCHH
SLSMVSFLEGLLGRRTSYEPLTSSEDIGKIRRIEKIISRFKTLSNFFS
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]