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The map label for this gene is fdhF-1 [H]

Identifier: 15897897

GI number: 15897897

Start: 887650

End: 889623

Strand: Direct

Name: fdhF-1 [H]

Synonym: SSO1029

Alternate gene names: 15897897

Gene position: 887650-889623 (Clockwise)

Preceding gene: 15897896

Following gene: 15897898

Centisome position: 29.67

GC content: 38.2

Gene sequence:

>1974_bases
ATGGAAGTTAGGAAAACCATATGCCCTTTCTGTGGTGTAGGTTGTGGTCTAGATTTTTATGTAGAGAATAACTTTATATT
TAGGGTATCTCCATCACAAGAGCACATTGTTAGCAGAGGACACGTTTGCGGTAAGGGCGCTGTTGCTTCAGAAGTAATTT
ACGCCTGGGACCGTTTAACTTATCCTTTAAAGAGAGTTAAGGACACTTTCGTTAGGACTACTTGGGATGAAGCAATTAGC
GATATTGCTAGCAAGTTAAAGGAAATTAGGAGTAAGTATGGCTCAGAGGCTATTGCCTTTTACGGGGGTTGTCAGAATAC
GTTGGAGGAAGGATATTCGTTCATGAAGTTGGCTAGAGCTTTGGGTACTAATAATGTTGACTCGTGTGCTAGGGTTTGTC
ATGAGCCCTCTGCAATGGCTTTAAAGGAGTTAGTCGGTATTGGAGCTTCTTCTGTTACCGTTTCTGAAATTTTGAATGCT
AGAAATATTGTAATTTCTGGAGAATCTGTGACTGATAGCCATCCCGTTTTGTCTCAATATTTAGTTGAGGCTAAGAGAAA
GGGTGTGAAAATTGTAGTTATTGATCCTAGGATGACTGGTACTGCTAGGATTGCTGATTTGTTTTTACAGATTAGTAGTG
GTACTGATATTTATCTATATAACGCTGTTGCGAATTATTTGATAAGTAACGGATTATATGATAGTAAGTTCGTTAAGGAA
CGTGTTGAGAACTTTGATGAGTTTAGGGAGATTGTAAAGTCTTATACTATTGAGGAAGCCGAGAGGATTACTAGTGTTAG
TAAGGATAAGATTATTGAGTTCGCTAGGATTATTGCAAATAAGCCTACAATACTCTCATGGGGTTTGGGTTTAACTCAGT
CAAGTGGCGTTAATGCCGTAAAGGCTTACATTAACCTAGCATTGCTTACTGGGAATGTTGGTATTAATGGTGGGGGACTA
TTAGTTTATAGGGGTCAAACAAATGTTCAAGGTTCTGGTGATTTAATAAAGCCAGATGTTTTCCCAAATGGTCCAATGAA
TGAGGAAAACGCTAAGGAGTTGAGTAAGATTTGGGGTTTTGTTCCTCCAATCAAGAAGGGTTTGAGCATAACTGAGGCTT
TTCTAAGGGATAGTAATGTTAAGGCACTTTTTCTAATGAATTACAATCCAGCTTTTAGTTTGCCAAATAGATACAAGGTT
ATTAAGTTCTTGAAGTCGTTGGAATTGTTAGTAGTAATGGATCCGTTTATGACTGAGACTGCTAAATATGCACATTACGT
TTTGCCTACTCCTTTATGGGCTGAAAAGGAGGGTTCAGTTACTAATTTAGATCGTACTGTTAAGTGGAGGTTTAAGGTTG
TTGATCCTCCTGGGGAGGTTAGGAGTGAGTTGTGGATAATTAAGAGGATTGCTGAGAAGTTAGGTCTTACTGGTTTTCAT
GACGATCCTAAATTGGTGTTTAAAGAGATAAAGGAGGTTGCAAAGTTGTACTCTAATTTGACCCTTGATGAATTGATGGA
TTACTCTGTAGACTCCAGGTATCCTGATCACGAGTCTAGTCTGTACAAGGATAGGTTTATGACTCCTAGCGGTAAGGCTA
AGTTTGGATTAGTTAGGTATAACGAAATATCTGGTGATAGTTACATTTTAATTACTGGTAGAGTTGTGACTAGGTATAAT
TCTGATGAGTTGATCAAGAGAGTCCCAGGATATAGGAATTTCAGTTCTGATTTGTTGATAAACCCAGAGGATGCTACAAA
GCTGAATATCAAAGACGGGGATATGGTTAAGGTTGTTTCTAAATGCGGCATGGCTGTGATGAAAGCCAAGCTAACTAACG
AGGTTAAGGTTGGTCATACGTTTGCTTATATGCATGATTACTATGTAAACAACGTTGTCTGTGACGATTTAGATGATATT
TCTAAGACTCCAAGATATAAGATAACCTTTGTCAAGATTGAAAAATTGGGATAA

Upstream 100 bases:

>100_bases
CAATAATTTTTTCAAAGCTTATGGAGTAAACCCAGTTAATAATTGATATTAATACGGATAGTAAGATCGTTTTAAATTTT
CTAGATCAGTATACTATTGT

Downstream 100 bases:

>100_bases
ATTATTTTTAAAAAGGAAGGTGTTTCTCTATATATGTCTGAAGTTGCTATTGTAACCGGAGCATCAAAAGGTATAGGGAG
AGCTGTTGTTAAGTTACTTA

Product: formate dehydrogenase Alpha subunit (fdhF-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MEVRKTICPFCGVGCGLDFYVENNFIFRVSPSQEHIVSRGHVCGKGAVASEVIYAWDRLTYPLKRVKDTFVRTTWDEAIS
DIASKLKEIRSKYGSEAIAFYGGCQNTLEEGYSFMKLARALGTNNVDSCARVCHEPSAMALKELVGIGASSVTVSEILNA
RNIVISGESVTDSHPVLSQYLVEAKRKGVKIVVIDPRMTGTARIADLFLQISSGTDIYLYNAVANYLISNGLYDSKFVKE
RVENFDEFREIVKSYTIEEAERITSVSKDKIIEFARIIANKPTILSWGLGLTQSSGVNAVKAYINLALLTGNVGINGGGL
LVYRGQTNVQGSGDLIKPDVFPNGPMNEENAKELSKIWGFVPPIKKGLSITEAFLRDSNVKALFLMNYNPAFSLPNRYKV
IKFLKSLELLVVMDPFMTETAKYAHYVLPTPLWAEKEGSVTNLDRTVKWRFKVVDPPGEVRSELWIIKRIAEKLGLTGFH
DDPKLVFKEIKEVAKLYSNLTLDELMDYSVDSRYPDHESSLYKDRFMTPSGKAKFGLVRYNEISGDSYILITGRVVTRYN
SDELIKRVPGYRNFSSDLLINPEDATKLNIKDGDMVKVVSKCGMAVMKAKLTNEVKVGHTFAYMHDYYVNNVVCDDLDDI
SKTPRYKITFVKIEKLG

Sequences:

>Translated_657_residues
MEVRKTICPFCGVGCGLDFYVENNFIFRVSPSQEHIVSRGHVCGKGAVASEVIYAWDRLTYPLKRVKDTFVRTTWDEAIS
DIASKLKEIRSKYGSEAIAFYGGCQNTLEEGYSFMKLARALGTNNVDSCARVCHEPSAMALKELVGIGASSVTVSEILNA
RNIVISGESVTDSHPVLSQYLVEAKRKGVKIVVIDPRMTGTARIADLFLQISSGTDIYLYNAVANYLISNGLYDSKFVKE
RVENFDEFREIVKSYTIEEAERITSVSKDKIIEFARIIANKPTILSWGLGLTQSSGVNAVKAYINLALLTGNVGINGGGL
LVYRGQTNVQGSGDLIKPDVFPNGPMNEENAKELSKIWGFVPPIKKGLSITEAFLRDSNVKALFLMNYNPAFSLPNRYKV
IKFLKSLELLVVMDPFMTETAKYAHYVLPTPLWAEKEGSVTNLDRTVKWRFKVVDPPGEVRSELWIIKRIAEKLGLTGFH
DDPKLVFKEIKEVAKLYSNLTLDELMDYSVDSRYPDHESSLYKDRFMTPSGKAKFGLVRYNEISGDSYILITGRVVTRYN
SDELIKRVPGYRNFSSDLLINPEDATKLNIKDGDMVKVVSKCGMAVMKAKLTNEVKVGHTFAYMHDYYVNNVVCDDLDDI
SKTPRYKITFVKIEKLG
>Mature_657_residues
MEVRKTICPFCGVGCGLDFYVENNFIFRVSPSQEHIVSRGHVCGKGAVASEVIYAWDRLTYPLKRVKDTFVRTTWDEAIS
DIASKLKEIRSKYGSEAIAFYGGCQNTLEEGYSFMKLARALGTNNVDSCARVCHEPSAMALKELVGIGASSVTVSEILNA
RNIVISGESVTDSHPVLSQYLVEAKRKGVKIVVIDPRMTGTARIADLFLQISSGTDIYLYNAVANYLISNGLYDSKFVKE
RVENFDEFREIVKSYTIEEAERITSVSKDKIIEFARIIANKPTILSWGLGLTQSSGVNAVKAYINLALLTGNVGINGGGL
LVYRGQTNVQGSGDLIKPDVFPNGPMNEENAKELSKIWGFVPPIKKGLSITEAFLRDSNVKALFLMNYNPAFSLPNRYKV
IKFLKSLELLVVMDPFMTETAKYAHYVLPTPLWAEKEGSVTNLDRTVKWRFKVVDPPGEVRSELWIIKRIAEKLGLTGFH
DDPKLVFKEIKEVAKLYSNLTLDELMDYSVDSRYPDHESSLYKDRFMTPSGKAKFGLVRYNEISGDSYILITGRVVTRYN
SDELIKRVPGYRNFSSDLLINPEDATKLNIKDGDMVKVVSKCGMAVMKAKLTNEVKVGHTFAYMHDYYVNNVVCDDLDDI
SKTPRYKITFVKIEKLG

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=702, Percent_Identity=33.7606837606838, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI3868719, Length=619, Percent_Identity=26.1712439418417, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI3868720, Length=603, Percent_Identity=27.6948590381426, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1788534, Length=528, Percent_Identity=26.3257575757576, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787778, Length=679, Percent_Identity=24.4477172312224, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787870, Length=733, Percent_Identity=26.0572987721692, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI87081797, Length=722, Percent_Identity=24.792243767313, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI171474008, Length=731, Percent_Identity=24.8974008207934, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 73614; Mature: 73614

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRKTICPFCGVGCGLDFYVENNFIFRVSPSQEHIVSRGHVCGKGAVASEVIYAWDRLT
CCCHHHHCCHHCCCCCEEEEEECCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YPLKRVKDTFVRTTWDEAISDIASKLKEIRSKYGSEAIAFYGGCQNTLEEGYSFMKLARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LGTNNVDSCARVCHEPSAMALKELVGIGASSVTVSEILNARNIVISGESVTDSHPVLSQY
HCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEHHHHHCCCEEEEECCCCCCCCHHHHHH
LVEAKRKGVKIVVIDPRMTGTARIADLFLQISSGTDIYLYNAVANYLISNGLYDSKFVKE
HHHHHHCCCEEEEECCCCCCHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCCCCHHHHHH
RVENFDEFREIVKSYTIEEAERITSVSKDKIIEFARIIANKPTILSWGLGLTQSSGVNAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHH
KAYINLALLTGNVGINGGGLLVYRGQTNVQGSGDLIKPDVFPNGPMNEENAKELSKIWGF
HHHHEEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCC
VPPIKKGLSITEAFLRDSNVKALFLMNYNPAFSLPNRYKVIKFLKSLELLVVMDPFMTET
CCCHHHCCHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHH
AKYAHYVLPTPLWAEKEGSVTNLDRTVKWRFKVVDPPGEVRSELWIIKRIAEKLGLTGFH
HHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
DDPKLVFKEIKEVAKLYSNLTLDELMDYSVDSRYPDHESSLYKDRFMTPSGKAKFGLVRY
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEE
NEISGDSYILITGRVVTRYNSDELIKRVPGYRNFSSDLLINPEDATKLNIKDGDMVKVVS
EECCCCEEEEEEEEEEEECCHHHHHHHCCCCCCCCCCEEECCCCCCEEECCCCHHHHHHH
KCGMAVMKAKLTNEVKVGHTFAYMHDYYVNNVVCDDLDDISKTPRYKITFVKIEKLG
HCCHHHHHHHHCCCEECCEEEEHHHHHHHCCEECCCCHHHCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MEVRKTICPFCGVGCGLDFYVENNFIFRVSPSQEHIVSRGHVCGKGAVASEVIYAWDRLT
CCCHHHHCCHHCCCCCEEEEEECCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YPLKRVKDTFVRTTWDEAISDIASKLKEIRSKYGSEAIAFYGGCQNTLEEGYSFMKLARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LGTNNVDSCARVCHEPSAMALKELVGIGASSVTVSEILNARNIVISGESVTDSHPVLSQY
HCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEHHHHHCCCEEEEECCCCCCCCHHHHHH
LVEAKRKGVKIVVIDPRMTGTARIADLFLQISSGTDIYLYNAVANYLISNGLYDSKFVKE
HHHHHHCCCEEEEECCCCCCHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCCCCHHHHHH
RVENFDEFREIVKSYTIEEAERITSVSKDKIIEFARIIANKPTILSWGLGLTQSSGVNAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHH
KAYINLALLTGNVGINGGGLLVYRGQTNVQGSGDLIKPDVFPNGPMNEENAKELSKIWGF
HHHHEEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCC
VPPIKKGLSITEAFLRDSNVKALFLMNYNPAFSLPNRYKVIKFLKSLELLVVMDPFMTET
CCCHHHCCHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHH
AKYAHYVLPTPLWAEKEGSVTNLDRTVKWRFKVVDPPGEVRSELWIIKRIAEKLGLTGFH
HHHHEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
DDPKLVFKEIKEVAKLYSNLTLDELMDYSVDSRYPDHESSLYKDRFMTPSGKAKFGLVRY
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEE
NEISGDSYILITGRVVTRYNSDELIKRVPGYRNFSSDLLINPEDATKLNIKDGDMVKVVS
EECCCCEEEEEEEEEEEECCHHHHHHHCCCCCCCCCCEEECCCCCCEEECCCCHHHHHHH
KCGMAVMKAKLTNEVKVGHTFAYMHDYYVNNVVCDDLDDISKTPRYKITFVKIEKLG
HCCHHHHHHHHCCCEECCEEEEHHHHHHHCCEECCCCHHHCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]