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The map label for this gene is eiF5A [H]

Identifier: 15897849

GI number: 15897849

Start: 829696

End: 830091

Strand: Direct

Name: eiF5A [H]

Synonym: SSO0970

Alternate gene names: 15897849

Gene position: 829696-830091 (Clockwise)

Preceding gene: 15897848

Following gene: 15897850

Centisome position: 27.73

GC content: 38.89

Gene sequence:

>396_bases
ATGAGCATAACGTACACGACCGTCGGTGAGCTCAAGGTAGGTAGTTATGTAGTAATAGATGGAGAGCCTTGTAGGGTTGT
AGAAGTAACTAAGGCTAAAACAGGTAAGCATGGAAGTGCAAAAGCTAACGTGGTAGCTATTGGGGTTTTTAGTGGAGCAA
AAAAGACACTAATGGCTCCAGTAGATCAGCAAGTTGAAGTTCCTATTATAGAAAAGCATATCGGTCAAATAATTGCAGAT
ATGGGTAATAAAATACAAGTAATGGATTTAGAAAGTTATGAGACCTTCGAGATCGAGAAACCAACAGAAGATGAGCTAGC
CTCCAAGATAAAACCTAATGCGGAATTAGAGTACTGGGAAATAATGGGAAGGAGAAAAATAGTTAGGGTTAAGTAA

Upstream 100 bases:

>100_bases
TAGCTAGGTCTGAAGAGTGATGAGGGGCCAAAGCTCGGAGCGTTTTTAATAAGAGTAAGAGTTTAAAGTTTAACACATTT
TATATCATAGAGGGTTAAAG

Downstream 100 bases:

>100_bases
TAATGTTAGAAAATATAAGAGATGCAGTAAGGAAGTTTCTTACAGGATCTACACCCTACGAGAAAGCAGTAGATGAGTTT
ATAAAAGATCTTCAGAAGTC

Product: translation initiation factor IF-5A

Products: NA

Alternate protein names: Hypusine-containing protein; eIF-5A [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIAD
MGNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWEIMGRRKIVRVK

Sequences:

>Translated_131_residues
MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIAD
MGNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWEIMGRRKIVRVK
>Mature_130_residues
SITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIADM
GNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWEIMGRRKIVRVK

Specific function: Functions by promoting the formation of the first peptide bond [H]

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-5A family [H]

Homologues:

Organism=Homo sapiens, GI9966867, Length=101, Percent_Identity=34.6534653465347, Blast_Score=64, Evalue=2e-11,
Organism=Homo sapiens, GI219555707, Length=69, Percent_Identity=39.1304347826087, Blast_Score=64, Evalue=5e-11,
Organism=Homo sapiens, GI219555712, Length=69, Percent_Identity=39.1304347826087, Blast_Score=63, Evalue=6e-11,
Organism=Homo sapiens, GI219555710, Length=69, Percent_Identity=39.1304347826087, Blast_Score=63, Evalue=6e-11,
Organism=Homo sapiens, GI4503545, Length=69, Percent_Identity=39.1304347826087, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17534327, Length=101, Percent_Identity=33.6633663366337, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71990399, Length=101, Percent_Identity=32.6732673267327, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320801, Length=101, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322507, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19922878, Length=111, Percent_Identity=31.5315315315315, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24762531, Length=111, Percent_Identity=31.5315315315315, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR019769
- InterPro:   IPR001884
- InterPro:   IPR022847
- InterPro:   IPR020189
- InterPro:   IPR013185
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF08207 EFP_N; PF01287 eIF-5a [H]

EC number: NA

Molecular weight: Translated: 14492; Mature: 14361

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00302 IF5A_HYPUSINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAP
CEEEEEEECCEEECCEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEECC
VDQQVEVPIIEKHIGQIIADMGNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWE
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHEE
IMGRRKIVRVK
ECCCCEEEEEC
>Mature Secondary Structure 
SITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAP
EEEEEEECCEEECCEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEECC
VDQQVEVPIIEKHIGQIIADMGNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWE
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHEE
IMGRRKIVRVK
ECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA