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The map label for this gene is eiF4A

Identifier: 15897631

GI number: 15897631

Start: 622874

End: 623575

Strand: Reverse

Name: eiF4A

Synonym: SSO0729

Alternate gene names: NA

Gene position: 623575-622874 (Counterclockwise)

Preceding gene: 15897632

Following gene: 15897630

Centisome position: 20.84

GC content: 30.91

Gene sequence:

>702_bases
ATGGTAATTAGAATTTATGCTGATGATAGGGAAAAGGCTAGTGGCATACCAGAATTATTAAAGGAGTTAGGAATTACAGT
AATATTTTCTCAACTTACTGTAGCTGATTATGTAATAACTGATGATGTTGCAGTAGAGAGGAAATCAGTAAATGATCTAG
TAAATTCAGTTTTTGACAAAAGGTTTTTTGACCAAATTAGCAGGCTTTCAGAGGTTTATCGTTTTCCAATATTACTCGTA
GAGGGCGATATTAATGATATTAGGAAGATAACTGAAAAGTGGAGAGCAATTAACAATGCGTTAATTTCTGCTACAATTGA
TTATGATGTTAAAGTGTTTTATTCTAGGGACAAAAAAGATACGGCAGAAGTTTTGAAAAAAATAGCTGAAAAATTCCAAT
TTGGTGAAAACAAGAGTAATCGAATTAGTTTACATAATAAGGCTAAATTGGAAAGTGTTTCTGATATACAACTTTACATT
GTAGAGTCTTTTCCTAATGTTGGTTCTATCCTAGCCGAAAGGCTACTACTTAAGTTTGGAACTATACAGAATATTTGCAA
TGCATCTATATCAGAACTGGAAAAAGCACTAGGTAGTAGGAAAAAAGCTGAAGATATTTATAAAATTTTAAGGACGCATT
ATTCTAAAACTAACTTAGATAATGATAGTAAGAAAACTACCTCTTTATTTGATTTCCTTTAG

Upstream 100 bases:

>100_bases
AGAAGACTTGCAGGCTAAAATAAATGACATGCTATCGAAGTATTATCCGCAAGGTGGCCAAACAGGTATAAAAGCTTAAG
CAAAGTAACTTATTAGTGTT

Downstream 100 bases:

>100_bases
ATTTTTTAGTCTCTTTTTTAGCATTACCTTTTAATATGGGTCTAAATAAGTTTAAGTGCAAGAAGTTGGTGATTTCATTT
GCCTAGATATAAGACAGTAG

Product: RNA helicase (ATP dependent)/eIF4A (eiF4A)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRFFDQISRLSEVYRFPILLV
EGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYI
VESFPNVGSILAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL

Sequences:

>Translated_233_residues
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRFFDQISRLSEVYRFPILLV
EGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYI
VESFPNVGSILAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL
>Mature_233_residues
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRFFDQISRLSEVYRFPILLV
EGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYI
VESFPNVGSILAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL

Specific function: Unknown

COG id: COG1948

COG function: function code L; ERCC4-type nuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI74959747, Length=199, Percent_Identity=26.1306532663317, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4885217, Length=236, Percent_Identity=24.1525423728814, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325235, Length=79, Percent_Identity=43.0379746835443, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17933560, Length=225, Percent_Identity=26.2222222222222, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994 [H]

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 26683; Mature: 26683

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDK
CEEEEEECCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RFFDQISRLSEVYRFPILLVEGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKD
HHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCH
TAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYIVESFPNVGSILAERLLLKFG
HHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHH
TIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDK
CEEEEEECCCHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RFFDQISRLSEVYRFPILLVEGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKD
HHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCH
TAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYIVESFPNVGSILAERLLLKFG
HHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHHHH
TIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]