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The map label for this gene is pyrI [H]

Identifier: 15897529

GI number: 15897529

Start: 534485

End: 534976

Strand: Reverse

Name: pyrI [H]

Synonym: SSO0613

Alternate gene names: 15897529

Gene position: 534976-534485 (Counterclockwise)

Preceding gene: 15897530

Following gene: 15897528

Centisome position: 17.88

GC content: 33.94

Gene sequence:

>492_bases
GTGATAGGGAAGATGATTAGCTCTTCAAAAAGGGATGAATTAATTGTAAGTAAAATAAGGAATGGTACAGTAATTGATCA
CATTCCAGCTGGTAGAGCATTGGCAGTATTGAGAATTCTAGGGATAAGAGGAAGTGAGGGCTATAGAGTAGCTCTAGTTA
TGAATGTGGAAAGTAAAAAAATAGGAAGGAAAGATATAGTGAAAATTGAGGACAGAGTGATTGATGAGAAAGAAGCTAGT
CTAATAACACTAATAGCGCCGTCTGCTACCATAAACATTATAAGAGATTACGTGGTGACAGAGAAAAGACATTTAGAAGT
TCCAAAACAGATTAGAGGATTAATAAAATGTCCTAATCCCCAATGTATAACAAATAATGATGTTGAAGCGGAAAGTAGAT
TTATAACGATTTCAATTAAACCTCTTAAGCTAAAGTGTAAGTATTGTGAGATGTATATTACTGAAGATGATGTCATAAGG
CAGATACTATGA

Upstream 100 bases:

>100_bases
GAAATAGACAGGAGAGTTGATAAAACTGTAAACGCTAAATACTTCTATCAAGCGTCATTAGCTGTACCAGTTAGAATGGC
TCTATTTTACGAAGTTTTGG

Downstream 100 bases:

>100_bases
TATATTATGAAGTTATCGAGAAAAGGAAAAACGTAGATAATGTGTATGAAATAAAAATAGCTAACTTTAGCGTTAAACCA
AAAGCAGGACAATACGTGAG

Product: aspartate carbamoyltransferase regulatory subunit

Products: phosphate; N-carbamoyl-L-aspartate

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MIGKMISSSKRDELIVSKIRNGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKKIGRKDIVKIEDRVIDEKEAS
LITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNPQCITNNDVEAESRFITISIKPLKLKCKYCEMYITEDDVIR
QIL

Sequences:

>Translated_163_residues
MIGKMISSSKRDELIVSKIRNGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKKIGRKDIVKIEDRVIDEKEAS
LITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNPQCITNNDVEAESRFITISIKPLKLKCKYCEMYITEDDVIR
QIL
>Mature_163_residues
MIGKMISSSKRDELIVSKIRNGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKKIGRKDIVKIEDRVIDEKEAS
LITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNPQCITNNDVEAESRFITISIKPLKLKCKYCEMYITEDDVIR
QIL

Specific function: Involved in allosteric regulation of aspartate carbamoyltransferase [H]

COG id: COG1781

COG function: function code F; Aspartate carbamoyltransferase, regulatory subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrI family [H]

Homologues:

Organism=Escherichia coli, GI1790692, Length=148, Percent_Identity=33.7837837837838, Blast_Score=96, Evalue=8e-22,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020545
- InterPro:   IPR002801
- InterPro:   IPR020542
- ProDom:   PD006194 [H]

Pfam domain/function: PF01948 PyrI; PF02748 PyrI_C [H]

EC number: 2.1.3.2

Molecular weight: Translated: 18412; Mature: 18412

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKMISSSKRDELIVSKIRNGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKK
CCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEECCHHH
IGRKDIVKIEDRVIDEKEASLITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNP
CCCHHHEEHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCHHHHHHEECCCC
QCITNNDVEAESRFITISIKPLKLKCKYCEMYITEDDVIRQIL
CEECCCCCCCCCEEEEEEEEEEEEEEEEEEEEECCHHHHHHHC
>Mature Secondary Structure
MIGKMISSSKRDELIVSKIRNGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKK
CCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEECCHHH
IGRKDIVKIEDRVIDEKEASLITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNP
CCCHHHEEHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCHHHHHHEECCCC
QCITNNDVEAESRFITISIKPLKLKCKYCEMYITEDDVIRQIL
CEECCCCCCCCCEEEEEEEEEEEEEEEEEEEEECCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: carbamoyl phosphate; L-aspartate

Specific reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA