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The map label for this gene is topR-1

Identifier: 15897352

GI number: 15897352

Start: 365906

End: 369634

Strand: Direct

Name: topR-1

Synonym: SSO0420

Alternate gene names: 15897352

Gene position: 365906-369634 (Clockwise)

Preceding gene: 15897349

Following gene: 15897353

Centisome position: 12.23

GC content: 33.44

Gene sequence:

>3729_bases
TTGACAAGCATCAATAAAGTCCCACCCTCAATTTATACTAGGTCATGTCCCAATTGTGGAGGAAATATATCATCTCAGAG
ATTATTTAATGGTTCCGTATGCGAATCATGCCTAAAGGATGATAGAGAGTTTAGTAATTTATCTGATCTCATTAATATCC
TTTCTGAAAATAGTAATTTGAAAAATCTTACTCAAATACGTGATGTATTAGAAGAGTACAAGAAAGTTGAAGAAATATTC
GGTAAATTATTAAATAATTCAAAACCTATAGGTCCTCAAAGGTCGTGGACAATAAGGTTCTTAAGAGGAGAGAGTTTTGC
AATCATAGCACCTCCCGGTTTAGGTAAAACGACCTTTGGTTTAATAATGTCCCTATATAATGCTACTCGTAATAGGAAAT
CTATCATCATTTTCCCAACGAGGACCTTAATCTCACAAACAGTAGATAAATTGGCAAAATTTTCTGAATTGTACTCATAT
TCGCCTAGGATACTTTATAATAAGCAATCTCCTACTCAGACTGAGAACATATTAGACCAACTTAAGAGTGGGAATTTTGA
CATATTCATTTCAACGAATAGATTTGTAATTCAGAATTTATCTGAGTTATCAAATATAAAGTTTGACTTCATTTTCGTAG
ATGATGTCGACGCTGCGTTAAAGTCTGGAAAAAGTGCTAAGGCGATACTTCGGTTGGTAGGATTTACTGATGAAGACATT
CAAACGACCATGAAATTACTTAGAGAAAATATTGGGGAGGAGGAGAAGTTTGGAAAAATTCAAGAGATTAGAGAAAGTAG
GTTAAAGGACAAGATAGTAATTTTCTCCTCTGCAACCATTAGTAGAGGAAATCCCATACTCTCATCGCTTATGGGTTTTA
GACCCGGGAGTTCTGTGATATATCTAAGGAATATTTATGACTCTTATATTGATCTAACTCAAACTTGTAAAGGACAAGAT
TTTGAAGAGTGCACTCTTGGTACCGTTATCAAACTTCTTAAAAGACTTAATGATGGTACTTTGATTTTTGTACCCATAGA
TAAGGGTGCCCAATATGCAGACTATCTAGCTTCGAATTTGAGAGATCATGGGATAAATGTGGAATCTGTTGCATCATCTT
CTATCTCCAAACTGGAGAAATTTGAAAGAGGTGAGGTAAGCTCTTTAGTCGGAGTGGCTACACATTACGGAGTTTTAGTG
AGAGGAATAGACTTACCATGGAGGGTAAAATATTCAATATTTGTGGGGATACCAAAATTTAAGTTCAAAATTGGCGAATA
TATGCATCCATTAGCGTTAACCAGATTGCTAAGCTTAGTATACTTAGTGAAGAATGATGATAAAGTAAGGGGTCTACTTA
GTTATATTCGTAAGAGGTTAAGAAAAATAAGCCCTGCGGCCTTAGCGATGTTAGCTAAGGATATAAGAGAGGGAAAGATC
GATGATGAGAGGTTAAAGGAAGCATATAATTTAGTTAATGAGTATCTAAAAGATAATGAGTTTTTGAAAAAAGTATCTGA
TGTTGGAGATTTGGTAATAGAAGGGGATTATATTCTAATGCCAGATTACCTAACCTATATTCAAGCTAGTGGTAGAACAT
CTAGACTTTACGGCGCTAATTTAACTACTGGTCTTTCAGTATTATTAATAGATAATTCTAGATTATTTGAGTTACTTAAT
AAAAAATTAAATTTAATTTTAGATGAAGTAAAATGGTATTCACTAGATATTGATGCAGATAAACTTGGACAAGTAAGTCT
AAGCGATATCTCAGCTAAAATAACAGAAGAAAGAGAGAGTTTAAGTAAAATCAAGAAAGAAGGAAACGTCGAATCATCAT
CCCTTAGTGTTAAGACTACTTTATTTATAGTTGAATCTCCTAACAAGGCTAAGACTATTTCAAACTTCTTTTCTAGACCG
TCTACGAGATCATATGGTAAGCTTAGAGTTTATGAGACAGTACTTGGAGATAGAGTCTTAATTGTAGCAGCTAGTGGTGG
GCATATTTATGATCTAATAACGGAAGATGAAAGTGAAAAGCAAGATGACAACTACGTGTATGGAGTACTAGTGAAAGATA
GTAAATTTATTCCAATTTATTCTACTATAAAGAAATGTGAAAAAGGTCATCAGATAGTAAAAGATCTAAGTCAAAATAAA
TGCCCTATTTGTGGATCCAGAATAGTAACTGACAAAACAGAAGTAGTAGATATATTAAGGAAACTGGCTCTTGAAGTAGA
CGAAGTTCTTATAGGTACTGACCCTGATACTGAAGGGGAAAAGATTGCTTGGGATATATATCTGGCTATCCGTCCGTTTA
ATGGTAATATAAAAAGGGCAGAATTTCATGAGGTTACCAGAAGAGCGATACTTAATGCAATAAAGAACCCGAGGGAATTT
AACGATAACCTAGTTAAATCTCAAATTGTAAGAAGAATTGAGGATAGATGGATTGGATTTAAATTATCACGAAAACTACA
AACAGAATTTTGGGAACAACACTGTACATCTATATCTAAGAAAAATAGCAAAGATGAAGAATGCAAAGAAAATCGTAATC
TAAGTGCGGGTAGAGTCCAAACTCCAGTATTGGATTGGGTAGTTAATAGATACCAAAAATATAACGAAAATAAGAAGAAG
TACCTTATTATAGAGTCTCAAGATAAATCAATCTTTCCCTTTAGTGTATTGGCTTTAAAGAAGAATGGCTTATCTAAAAA
TACTCAAATAATTATACATCTAGAAGATATAAATATAAAAGAAGAGGAATTTGGACCCTTGCCACCATACACTACGGATA
CACTACTATCTGACGCTGCTAACCTTTTGAGAATTCCCGCATCAGATACTATGAGAGTAGCCCAAGATCTTTTCGAATTA
GGTTTGATAACTTATCATAGAACTGATAGTACTAGGGTATCAAATGTTGGTATAAGTGTAGCAGAAACTTATCTTAAATC
TAAACAAGTTGACATTTCCAAAATATTTAGACCAAGATCTTGGGGAGAAGGAGGTGCACATGAAGCTATAAGACCTACCA
AACCCCTAGATGAGACAATGTTAAAGGCATCCATAGAACAAGGGGACTTAGAACTATCCAAACAATTGACTTTTAACCAT
TTTAGAGTATATAATCTAATATTTAGGAGGTTCATTACTAGTCAACTACCACCACTAGTAGTAACTAAACAGATAGTTAG
GATAAGGGCGTATACTAAGGACAACATTGAATTGGAATTGGATGAGAATAAGAAGGAATTTGTTATTGGGTATAAATTAA
AGGAAGGAGATGAATTTAGACAAACATTACAAGACGCTATTTATACTCTATTTAGGCTTTATCAACCTTTAGATGAAAAA
ATGAAAGGGAAAGAGCTTTCTGCAACAATAACAGGCACATTAAATAAGAGTGATGTGCAGTTATATACTGAAGGAGAGTT
GATAAGTGAGATGAAAAGTAAACAAATCGGAAGACCGAGCACGTACGCAGTAATAATCTCTACTTTAAAGAAGAGAAGAT
ACATTATAGAATCAAAAAATTTGAAGAAAATAATACCAACTAAATTAGGTATGGCAGTAAAAGAGTATCTTATGGAAAAT
TATAAACAGATAGTATCTGAGAAACGAACTGTGAAATTACTGGAAAAGATGAACGAGGTAGAGGAGGGTAAAGTTGATTA
TTTAGTACTCTTAAAAGAATTATATAATGAAATACAAACAATTAGTTAG

Upstream 100 bases:

>100_bases
GCCTCTACCACTCTCAATTTCAATTGTTGGGACATATTATTCATCTTTCCGAAACGTTTAAAATAAGTCTTACTCATTAA
AACTATACGAGATTGGGAAG

Downstream 100 bases:

>100_bases
GAATGGTGAAAAAGTTTATGCTTATAGCTTTAGTCCATTTAAGGCTTAAAGAATTGTCAAGGAAACATAATCTAGAGAAA
GCTAAAAAACTAATAAGACA

Product: reverse gyrase

Products: NA

Alternate protein names: Helicase; Topoisomerase

Number of amino acids: Translated: 1242; Mature: 1241

Protein sequence:

>1242_residues
MTSINKVPPSIYTRSCPNCGGNISSQRLFNGSVCESCLKDDREFSNLSDLINILSENSNLKNLTQIRDVLEEYKKVEEIF
GKLLNNSKPIGPQRSWTIRFLRGESFAIIAPPGLGKTTFGLIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSELYSY
SPRILYNKQSPTQTENILDQLKSGNFDIFISTNRFVIQNLSELSNIKFDFIFVDDVDAALKSGKSAKAILRLVGFTDEDI
QTTMKLLRENIGEEEKFGKIQEIRESRLKDKIVIFSSATISRGNPILSSLMGFRPGSSVIYLRNIYDSYIDLTQTCKGQD
FEECTLGTVIKLLKRLNDGTLIFVPIDKGAQYADYLASNLRDHGINVESVASSSISKLEKFERGEVSSLVGVATHYGVLV
RGIDLPWRVKYSIFVGIPKFKFKIGEYMHPLALTRLLSLVYLVKNDDKVRGLLSYIRKRLRKISPAALAMLAKDIREGKI
DDERLKEAYNLVNEYLKDNEFLKKVSDVGDLVIEGDYILMPDYLTYIQASGRTSRLYGANLTTGLSVLLIDNSRLFELLN
KKLNLILDEVKWYSLDIDADKLGQVSLSDISAKITEERESLSKIKKEGNVESSSLSVKTTLFIVESPNKAKTISNFFSRP
STRSYGKLRVYETVLGDRVLIVAASGGHIYDLITEDESEKQDDNYVYGVLVKDSKFIPIYSTIKKCEKGHQIVKDLSQNK
CPICGSRIVTDKTEVVDILRKLALEVDEVLIGTDPDTEGEKIAWDIYLAIRPFNGNIKRAEFHEVTRRAILNAIKNPREF
NDNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCTSISKKNSKDEECKENRNLSAGRVQTPVLDWVVNRYQKYNENKKK
YLIIESQDKSIFPFSVLALKKNGLSKNTQIIIHLEDINIKEEEFGPLPPYTTDTLLSDAANLLRIPASDTMRVAQDLFEL
GLITYHRTDSTRVSNVGISVAETYLKSKQVDISKIFRPRSWGEGGAHEAIRPTKPLDETMLKASIEQGDLELSKQLTFNH
FRVYNLIFRRFITSQLPPLVVTKQIVRIRAYTKDNIELELDENKKEFVIGYKLKEGDEFRQTLQDAIYTLFRLYQPLDEK
MKGKELSATITGTLNKSDVQLYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMEN
YKQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS

Sequences:

>Translated_1242_residues
MTSINKVPPSIYTRSCPNCGGNISSQRLFNGSVCESCLKDDREFSNLSDLINILSENSNLKNLTQIRDVLEEYKKVEEIF
GKLLNNSKPIGPQRSWTIRFLRGESFAIIAPPGLGKTTFGLIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSELYSY
SPRILYNKQSPTQTENILDQLKSGNFDIFISTNRFVIQNLSELSNIKFDFIFVDDVDAALKSGKSAKAILRLVGFTDEDI
QTTMKLLRENIGEEEKFGKIQEIRESRLKDKIVIFSSATISRGNPILSSLMGFRPGSSVIYLRNIYDSYIDLTQTCKGQD
FEECTLGTVIKLLKRLNDGTLIFVPIDKGAQYADYLASNLRDHGINVESVASSSISKLEKFERGEVSSLVGVATHYGVLV
RGIDLPWRVKYSIFVGIPKFKFKIGEYMHPLALTRLLSLVYLVKNDDKVRGLLSYIRKRLRKISPAALAMLAKDIREGKI
DDERLKEAYNLVNEYLKDNEFLKKVSDVGDLVIEGDYILMPDYLTYIQASGRTSRLYGANLTTGLSVLLIDNSRLFELLN
KKLNLILDEVKWYSLDIDADKLGQVSLSDISAKITEERESLSKIKKEGNVESSSLSVKTTLFIVESPNKAKTISNFFSRP
STRSYGKLRVYETVLGDRVLIVAASGGHIYDLITEDESEKQDDNYVYGVLVKDSKFIPIYSTIKKCEKGHQIVKDLSQNK
CPICGSRIVTDKTEVVDILRKLALEVDEVLIGTDPDTEGEKIAWDIYLAIRPFNGNIKRAEFHEVTRRAILNAIKNPREF
NDNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCTSISKKNSKDEECKENRNLSAGRVQTPVLDWVVNRYQKYNENKKK
YLIIESQDKSIFPFSVLALKKNGLSKNTQIIIHLEDINIKEEEFGPLPPYTTDTLLSDAANLLRIPASDTMRVAQDLFEL
GLITYHRTDSTRVSNVGISVAETYLKSKQVDISKIFRPRSWGEGGAHEAIRPTKPLDETMLKASIEQGDLELSKQLTFNH
FRVYNLIFRRFITSQLPPLVVTKQIVRIRAYTKDNIELELDENKKEFVIGYKLKEGDEFRQTLQDAIYTLFRLYQPLDEK
MKGKELSATITGTLNKSDVQLYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMEN
YKQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS
>Mature_1241_residues
TSINKVPPSIYTRSCPNCGGNISSQRLFNGSVCESCLKDDREFSNLSDLINILSENSNLKNLTQIRDVLEEYKKVEEIFG
KLLNNSKPIGPQRSWTIRFLRGESFAIIAPPGLGKTTFGLIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSELYSYS
PRILYNKQSPTQTENILDQLKSGNFDIFISTNRFVIQNLSELSNIKFDFIFVDDVDAALKSGKSAKAILRLVGFTDEDIQ
TTMKLLRENIGEEEKFGKIQEIRESRLKDKIVIFSSATISRGNPILSSLMGFRPGSSVIYLRNIYDSYIDLTQTCKGQDF
EECTLGTVIKLLKRLNDGTLIFVPIDKGAQYADYLASNLRDHGINVESVASSSISKLEKFERGEVSSLVGVATHYGVLVR
GIDLPWRVKYSIFVGIPKFKFKIGEYMHPLALTRLLSLVYLVKNDDKVRGLLSYIRKRLRKISPAALAMLAKDIREGKID
DERLKEAYNLVNEYLKDNEFLKKVSDVGDLVIEGDYILMPDYLTYIQASGRTSRLYGANLTTGLSVLLIDNSRLFELLNK
KLNLILDEVKWYSLDIDADKLGQVSLSDISAKITEERESLSKIKKEGNVESSSLSVKTTLFIVESPNKAKTISNFFSRPS
TRSYGKLRVYETVLGDRVLIVAASGGHIYDLITEDESEKQDDNYVYGVLVKDSKFIPIYSTIKKCEKGHQIVKDLSQNKC
PICGSRIVTDKTEVVDILRKLALEVDEVLIGTDPDTEGEKIAWDIYLAIRPFNGNIKRAEFHEVTRRAILNAIKNPREFN
DNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCTSISKKNSKDEECKENRNLSAGRVQTPVLDWVVNRYQKYNENKKKY
LIIESQDKSIFPFSVLALKKNGLSKNTQIIIHLEDINIKEEEFGPLPPYTTDTLLSDAANLLRIPASDTMRVAQDLFELG
LITYHRTDSTRVSNVGISVAETYLKSKQVDISKIFRPRSWGEGGAHEAIRPTKPLDETMLKASIEQGDLELSKQLTFNHF
RVYNLIFRRFITSQLPPLVVTKQIVRIRAYTKDNIELELDENKKEFVIGYKLKEGDEFRQTLQDAIYTLFRLYQPLDEKM
KGKELSATITGTLNKSDVQLYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMENY
KQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS

Specific function: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DN

COG id: COG1110

COG function: function code L; Reverse gyrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain

Homologues:

Organism=Escherichia coli, GI1787529, Length=660, Percent_Identity=26.969696969697, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17555378, Length=504, Percent_Identity=25.3968253968254, Blast_Score=77, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323263, Length=342, Percent_Identity=24.5614035087719, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RGYR1_SULSO (Q97ZZ8)

Other databases:

- EMBL:   AE006641
- PIR:   D90186
- RefSeq:   NP_341957.1
- ProteinModelPortal:   Q97ZZ8
- GeneID:   1455557
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0420
- NMPDR:   fig|273057.1.peg.380
- HOGENOM:   HBG312311
- OMA:   RIAQDLF
- ProtClustDB:   PRK09401
- BioCyc:   SSOL273057:SSO0420-MONOMER
- BRENDA:   5.99.1.3
- GO:   GO:0005694
- HAMAP:   MF_01125
- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR005736
- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013826
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR006171
- Gene3D:   G3DSA:1.10.460.10
- Gene3D:   G3DSA:1.10.290.10
- PANTHER:   PTHR11390
- PRINTS:   PR00417
- SMART:   SM00382
- SMART:   SM00487
- SMART:   SM00437
- SMART:   SM00436
- SMART:   SM00493
- TIGRFAMs:   TIGR01054

Pfam domain/function: PF00270 DEAD; PF01131 Topoisom_bac; PF01751 Toprim; SSF56712 Topo_IA_core

EC number: =3.6.4.12; =5.99.1.3

Molecular weight: Translated: 141670; Mature: 141539

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS51192 HELICASE_ATP_BIND_1

Important sites: ACT_SITE 965-965 BINDING 93-93

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSINKVPPSIYTRSCPNCGGNISSQRLFNGSVCESCLKDDREFSNLSDLINILSENSNL
CCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCH
KNLTQIRDVLEEYKKVEEIFGKLLNNSKPIGPQRSWTIRFLRGESFAIIAPPGLGKTTFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHH
LIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSELYSYSPRILYNKQSPTQTENILDQ
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHH
LKSGNFDIFISTNRFVIQNLSELSNIKFDFIFVDDVDAALKSGKSAKAILRLVGFTDEDI
HHCCCEEEEEECCHHHHHHHHHHHCCEEEEEEECCHHHHHHCCCHHHHHHHHHCCCCHHH
QTTMKLLRENIGEEEKFGKIQEIRESRLKDKIVIFSSATISRGNPILSSLMGFRPGSSVI
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEE
YLRNIYDSYIDLTQTCKGQDFEECTLGTVIKLLKRLNDGTLIFVPIDKGAQYADYLASNL
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
RDHGINVESVASSSISKLEKFERGEVSSLVGVATHYGVLVRGIDLPWRVKYSIFVGIPKF
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCHH
KFKIGEYMHPLALTRLLSLVYLVKNDDKVRGLLSYIRKRLRKISPAALAMLAKDIREGKI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
DDERLKEAYNLVNEYLKDNEFLKKVSDVGDLVIEGDYILMPDYLTYIQASGRTSRLYGAN
CHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCEEECCCHHHHHHCCCCCCEEECCC
LTTGLSVLLIDNSRLFELLNKKLNLILDEVKWYSLDIDADKLGQVSLSDISAKITEERES
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCEEHHHHHHHHHHHHHH
LSKIKKEGNVESSSLSVKTTLFIVESPNKAKTISNFFSRPSTRSYGKLRVYETVLGDRVL
HHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEHHHHCCEEE
IVAASGGHIYDLITEDESEKQDDNYVYGVLVKDSKFIPIYSTIKKCEKGHQIVKDLSQNK
EEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
CPICGSRIVTDKTEVVDILRKLALEVDEVLIGTDPDTEGEKIAWDIYLAIRPFNGNIKRA
CCCCCCCEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEEEEEECCCCCCCHH
EFHEVTRRAILNAIKNPREFNDNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCTSISK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KNSKDEECKENRNLSAGRVQTPVLDWVVNRYQKYNENKKKYLIIESQDKSIFPFSVLALK
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEE
KNGLSKNTQIIIHLEDINIKEEEFGPLPPYTTDTLLSDAANLLRIPASDTMRVAQDLFEL
CCCCCCCCEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHH
GLITYHRTDSTRVSNVGISVAETYLKSKQVDISKIFRPRSWGEGGAHEAIRPTKPLDETM
HCEEEECCCCCCHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LKASIEQGDLELSKQLTFNHFRVYNLIFRRFITSQLPPLVVTKQIVRIRAYTKDNIELEL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEE
DENKKEFVIGYKLKEGDEFRQTLQDAIYTLFRLYQPLDEKMKGKELSATITGTLNKSDVQ
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEE
LYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMEN
EEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YKQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSINKVPPSIYTRSCPNCGGNISSQRLFNGSVCESCLKDDREFSNLSDLINILSENSNL
CCCCCCCCCHHHCCCCCCCCCCCCHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCH
KNLTQIRDVLEEYKKVEEIFGKLLNNSKPIGPQRSWTIRFLRGESFAIIAPPGLGKTTFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHH
LIMSLYNATRNRKSIIIFPTRTLISQTVDKLAKFSELYSYSPRILYNKQSPTQTENILDQ
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHH
LKSGNFDIFISTNRFVIQNLSELSNIKFDFIFVDDVDAALKSGKSAKAILRLVGFTDEDI
HHCCCEEEEEECCHHHHHHHHHHHCCEEEEEEECCHHHHHHCCCHHHHHHHHHCCCCHHH
QTTMKLLRENIGEEEKFGKIQEIRESRLKDKIVIFSSATISRGNPILSSLMGFRPGSSVI
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCEE
YLRNIYDSYIDLTQTCKGQDFEECTLGTVIKLLKRLNDGTLIFVPIDKGAQYADYLASNL
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
RDHGINVESVASSSISKLEKFERGEVSSLVGVATHYGVLVRGIDLPWRVKYSIFVGIPKF
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECCHH
KFKIGEYMHPLALTRLLSLVYLVKNDDKVRGLLSYIRKRLRKISPAALAMLAKDIREGKI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
DDERLKEAYNLVNEYLKDNEFLKKVSDVGDLVIEGDYILMPDYLTYIQASGRTSRLYGAN
CHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCEEECCCHHHHHHCCCCCCEEECCC
LTTGLSVLLIDNSRLFELLNKKLNLILDEVKWYSLDIDADKLGQVSLSDISAKITEERES
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCEEHHHHHHHHHHHHHH
LSKIKKEGNVESSSLSVKTTLFIVESPNKAKTISNFFSRPSTRSYGKLRVYETVLGDRVL
HHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEHHHHCCEEE
IVAASGGHIYDLITEDESEKQDDNYVYGVLVKDSKFIPIYSTIKKCEKGHQIVKDLSQNK
EEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
CPICGSRIVTDKTEVVDILRKLALEVDEVLIGTDPDTEGEKIAWDIYLAIRPFNGNIKRA
CCCCCCCEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEEEEEECCCCCCCHH
EFHEVTRRAILNAIKNPREFNDNLVKSQIVRRIEDRWIGFKLSRKLQTEFWEQHCTSISK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KNSKDEECKENRNLSAGRVQTPVLDWVVNRYQKYNENKKKYLIIESQDKSIFPFSVLALK
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEE
KNGLSKNTQIIIHLEDINIKEEEFGPLPPYTTDTLLSDAANLLRIPASDTMRVAQDLFEL
CCCCCCCCEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHH
GLITYHRTDSTRVSNVGISVAETYLKSKQVDISKIFRPRSWGEGGAHEAIRPTKPLDETM
HCEEEECCCCCCHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LKASIEQGDLELSKQLTFNHFRVYNLIFRRFITSQLPPLVVTKQIVRIRAYTKDNIELEL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEE
DENKKEFVIGYKLKEGDEFRQTLQDAIYTLFRLYQPLDEKMKGKELSATITGTLNKSDVQ
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEE
LYTEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMAVKEYLMEN
EEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YKQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNEIQTIS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726