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The map label for this gene is pncB [H]

Identifier: 15897291

GI number: 15897291

Start: 301577

End: 302740

Strand: Direct

Name: pncB [H]

Synonym: SSO0354

Alternate gene names: 15897291

Gene position: 301577-302740 (Clockwise)

Preceding gene: 15897270

Following gene: 15897294

Centisome position: 10.08

GC content: 37.54

Gene sequence:

>1164_bases
ATGGAGTTTTATATAGCCGATTTTAAGCAGATTAAGGAGGGTAAAGTCACAGATATTTATTTTGAAAGAACATTAAAGAC
ACTAGAATATCTTGGGATTAAAGACGCTAAAGTAAGGATGGAAGTACATTCTTACGGTTTACCTAAAGGTTATGAATGGG
CTCTTTTTACTGGTTTAGAAGAAGTTCTTCATTTGTTGGAAGGAGTGCCAGTGAACGTTTATGCGATGCCAGAAGGTACC
TTATTTAAAGAAATAGAACCGGTAATGATAATAGAAGGCAACTATTTAGATTTTGGTATTTACGAGACTGCCTTCCTAGG
AATATTGAGGCATTATTCTAGCATATCTACTAAGGCAGCCAGACTTAAATTTCTTGCAATGGATAAAACATTATTTTTCT
TTGGCTTAAGATCTCTTCATCCTGCACTAGCCCCTATGGCAGATAGGGCAGCTTATATAGGCGGCATGGATGGAGTTTCT
GGTGCCATGAGTAAGGAATATCTAGGAGTTGACCCTTCAGGTACTATGCCTCATGCACTAATGCTTATTGTAGGTGATAA
CGTGAAAGCCTGGAAGGCTTTTGACGAGGCTATGGGATCTGAAGTTCCTAGAATAACCTTAGTTGATACATTTGAGGACG
AAAGAACTGAAGCCTTAAAGGCTGCAACTTTACTTGGTAAGAAATTATATGGTATAAGGTTAGATACGCCGTCAAGTAGA
AGAGGGAATTTTAGAAAAATTATTCAGGAGGTTAAATGGACGTTAAAGATACACGGTTATGATCATGTTAAGATATTTGC
AAGCGGAGGGATAGATGAGGACGATATAATTAACCTTCGAGATATTGTTGACGGATTTGGGATTGGAACGAGTATAGCAT
TTCCTCCAAGTGTTGATTTCAGTGCTGATATAGTGGAAAAATTTGTTGATGGTAAATGGGTGCCTTTTACAAAGAGAGGC
AAATGGCCCGGGGCTAAGCAAGTATATAGATGTGGAAAGCTAAATGATGTAATTACCCTTATGGACCAAGAACATCCTTC
TTCAGATTGTAAGCCTCTACTGCAAAAATATATGGAAAATGGAAAGATTATAAAACCTTTACCTTCTCCAAAAGAAATAA
GGGAATACGTGATTAAACAGTTAACTGAATTGCAGAGTAGCTAG

Upstream 100 bases:

>100_bases
ATCTGGAGGTACCATTTCAGCTGTTATCATTATAAGACTCAATTACATTCGTAGTATATAAGGTTTAAAATTTATCCTTT
TTAATAACATATGATCTCGA

Downstream 100 bases:

>100_bases
CCTGTTATTATAATTTCTTTTTGATTCTCTATGCTTCTGTTAAATGCTATTTCGGTTATTGGCTCCATTCTTCTTATTGC
GTTATATAACCTTAAGTTAA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLEEVLHLLEGVPVNVYAMPEGT
LFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAARLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVS
GAMSKEYLGVDPSGTMPHALMLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSR
RGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDFSADIVEKFVDGKWVPFTKRG
KWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMENGKIIKPLPSPKEIREYVIKQLTELQSS

Sequences:

>Translated_387_residues
MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLEEVLHLLEGVPVNVYAMPEGT
LFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAARLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVS
GAMSKEYLGVDPSGTMPHALMLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSR
RGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDFSADIVEKFVDGKWVPFTKRG
KWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMENGKIIKPLPSPKEIREYVIKQLTELQSS
>Mature_387_residues
MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLEEVLHLLEGVPVNVYAMPEGT
LFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAARLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVS
GAMSKEYLGVDPSGTMPHALMLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSR
RGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDFSADIVEKFVDGKWVPFTKRG
KWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMENGKIIKPLPSPKEIREYVIKQLTELQSS

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 43558; Mature: 43558

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLE
CCEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCHHHHHHHH
EVLHLLEGVPVNVYAMPEGTLFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAA
HHHHHHCCCCEEEEECCCCCHHHCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHH
RLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVSGAMSKEYLGVDPSGTMPHAL
HEEEEEECHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
MLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSR
EEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
RGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDF
CCCHHHHHHHHEEEEEEECCCEEEEEECCCCCHHHCEEHHHHHHHCCCCCCCCCCCCCCC
SADIVEKFVDGKWVPFTKRGKWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMEN
CHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHC
GKIIKPLPSPKEIREYVIKQLTELQSS
CCEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFYIADFKQIKEGKVTDIYFERTLKTLEYLGIKDAKVRMEVHSYGLPKGYEWALFTGLE
CCEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCHHHHHHHH
EVLHLLEGVPVNVYAMPEGTLFKEIEPVMIIEGNYLDFGIYETAFLGILRHYSSISTKAA
HHHHHHCCCCEEEEECCCCCHHHCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHH
RLKFLAMDKTLFFFGLRSLHPALAPMADRAAYIGGMDGVSGAMSKEYLGVDPSGTMPHAL
HEEEEEECHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEE
MLIVGDNVKAWKAFDEAMGSEVPRITLVDTFEDERTEALKAATLLGKKLYGIRLDTPSSR
EEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
RGNFRKIIQEVKWTLKIHGYDHVKIFASGGIDEDDIINLRDIVDGFGIGTSIAFPPSVDF
CCCHHHHHHHHEEEEEEECCCEEEEEECCCCCHHHCEEHHHHHHHCCCCCCCCCCCCCCC
SADIVEKFVDGKWVPFTKRGKWPGAKQVYRCGKLNDVITLMDQEHPSSDCKPLLQKYMEN
CHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHC
GKIIKPLPSPKEIREYVIKQLTELQSS
CCEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]