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The map label for this gene is NuoI [H]

Identifier: 15897266

GI number: 15897266

Start: 278497

End: 279063

Strand: Direct

Name: NuoI [H]

Synonym: SSO0326

Alternate gene names: 15897266

Gene position: 278497-279063 (Clockwise)

Preceding gene: 15897265

Following gene: 15897267

Centisome position: 9.31

GC content: 36.51

Gene sequence:

>567_bases
TTGGAAATATTTCTTTCCCTTAGCTTTAGCTTCCTTATTATTAGGTGTGGTGGTGGGTTATTTATGGATAAGGTGAAAGA
ATATAAAAAAGAAAATATAGCGAGTTTATTTGCAGAACATATACAGTCCATAGTTACGGGTATAAAATATTTTGTAAAGC
CTCAGAGAATCACACTGCAATATCCAGAAGATAGCCTTACTCTTCCTACGGGTTATAGAGGTATGATTAGGCTGTACAAA
GACGTATGTATAGGCTGTACTTTATGCGCTTTGATATGTCCCGCAGATGCGATGAAAATGGTTACAGAAAGTGGAAAGAA
GTTTCCGCAAATAAATTACGGTAGGTGCGTCTTCTGTGGTTTCTGTGTAGACGTATGTCCAGTGGATGCTTTAAAGGAAA
CTAAAGTACATGATCTTGTTTTTAATAACAGAAAACAACTGATCTTCGATCCGGATAGATTTAACGTAGATATAGATGAT
GTGCCTATGCAAGATAAGCCTGTAAGAAAAGTAAAAGCAATAATAGATGAGAAGAGGGGTATAAAATATGTACCCGCAGA
CGAGTGA

Upstream 100 bases:

>100_bases
CAATATTTACCGTTTTCAAGGCAGCAATAGTGGTATTTTTTGCTGTATTTCTTAGAGCGGTTTATGGAAGATACAGAATA
GATCAAGCTTTAAGGGGAAG

Downstream 100 bases:

>100_bases
GATAATACAATATATATTATTTGGTTTTTTTGGAGTTATGACTATAGCCTTCTCAATATATATTGTTAGGGCTAAGAATG
TGTTTTATGGTGCAGTGAGT

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 1; NDH-1 subunit I 1 [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEIFLSLSFSFLIIRCGGGLFMDKVKEYKKENIASLFAEHIQSIVTGIKYFVKPQRITLQYPEDSLTLPTGYRGMIRLYK
DVCIGCTLCALICPADAMKMVTESGKKFPQINYGRCVFCGFCVDVCPVDALKETKVHDLVFNNRKQLIFDPDRFNVDIDD
VPMQDKPVRKVKAIIDEKRGIKYVPADE

Sequences:

>Translated_188_residues
MEIFLSLSFSFLIIRCGGGLFMDKVKEYKKENIASLFAEHIQSIVTGIKYFVKPQRITLQYPEDSLTLPTGYRGMIRLYK
DVCIGCTLCALICPADAMKMVTESGKKFPQINYGRCVFCGFCVDVCPVDALKETKVHDLVFNNRKQLIFDPDRFNVDIDD
VPMQDKPVRKVKAIIDEKRGIKYVPADE
>Mature_188_residues
MEIFLSLSFSFLIIRCGGGLFMDKVKEYKKENIASLFAEHIQSIVTGIKYFVKPQRITLQYPEDSLTLPTGYRGMIRLYK
DVCIGCTLCALICPADAMKMVTESGKKFPQINYGRCVFCGFCVDVCPVDALKETKVHDLVFNNRKQLIFDPDRFNVDIDD
VPMQDKPVRKVKAIIDEKRGIKYVPADE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=141, Percent_Identity=28.3687943262411, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1788617, Length=138, Percent_Identity=35.5072463768116, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1789075, Length=113, Percent_Identity=30.9734513274336, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555194, Length=126, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17864306, Length=141, Percent_Identity=28.3687943262411, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21436; Mature: 21436

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFLSLSFSFLIIRCGGGLFMDKVKEYKKENIASLFAEHIQSIVTGIKYFVKPQRITLQ
CEEEEEEHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
YPEDSLTLPTGYRGMIRLYKDVCIGCTLCALICPADAMKMVTESGKKFPQINYGRCVFCG
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEHHH
FCVDVCPVDALKETKVHDLVFNNRKQLIFDPDRFNVDIDDVPMQDKPVRKVKAIIDEKRG
HHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
IKYVPADE
CCCCCCCC
>Mature Secondary Structure
MEIFLSLSFSFLIIRCGGGLFMDKVKEYKKENIASLFAEHIQSIVTGIKYFVKPQRITLQ
CEEEEEEHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
YPEDSLTLPTGYRGMIRLYKDVCIGCTLCALICPADAMKMVTESGKKFPQINYGRCVFCG
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEHHH
FCVDVCPVDALKETKVHDLVFNNRKQLIFDPDRFNVDIDDVPMQDKPVRKVKAIIDEKRG
HHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
IKYVPADE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA