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The map label for this gene is aroA

Identifier: 15897251

GI number: 15897251

Start: 262804

End: 264048

Strand: Direct

Name: aroA

Synonym: SSO0309

Alternate gene names: 15897251

Gene position: 262804-264048 (Clockwise)

Preceding gene: 15897250

Following gene: 15897252

Centisome position: 8.78

GC content: 34.06

Gene sequence:

>1245_bases
TTGATTGTAAAGATTTATCCATCAAAGATTAGTGGAATAATAAAAGCTCCTCAATCAAAAAGTCTAGCTATTAGGTTAAT
TTTTCTTTCACTTTTCACTAGAGTATATCTTCATAACTTAGTTCTATCGGAAGATGTTATAGACGCTATAAAATCAGTAA
GAGCATTAGGAGTAAAGGTAAAAAACAATTCTGAATTTATACCTCCAGAGAAATTAGAAATTAAGGAGAGGTTTATAAAA
TTAAAAGGTTCCGCTACTACTCTTAGAATGCTTATTCCAATATTAGCCGCAATAGGCGGAGAAGTGACAATTGATGCAGA
TGAGAGTTTAAGAAGGAGACCTTTAAACAGAATCGTACAAGCATTAAGTAACTACGGTATATCCTTTTCTTCTTACAGTT
TGCCTTTGACTATCACGGGAAAGTTAAGTAGTAATGAGATAAAGATTTCTGGTGATGAGAGTAGTCAATATATTTCTGGC
TTAATATACGCACTTCATATTCTAAATGGCGGTAGTATTGAAATATTGCCCCCCATTTCATCTAAAAGTTATATTCTGCT
TACAATAGATTTATTTAAGAGATTTGGTTCTGATGTTAAGTTTTATGGTAGTAAGATTCATGTTAATCCCAATAATTTGG
TTGAATTTCAAGGCGAAGTGGCGGGAGATTATGGTTTAGCCTCGTTTTACGCGCTTTCTGCATTAGTTAGTGGTGGAGGA
ATTACAATAACTAATTTGTGGGAGCCGAAGGAATATTTTGGTGATCATAGTATTGTTAAAATATTTAGTGAGATGGGCGC
TTCCAGTGAATATAAAGACGGTAGATGGTTTGTCAAGGCTAAAGATAAATATTCTCCCATAAAAATTGATATAGATGACG
CACCTGACCTGGCTATGACAATTGCGGGATTATCTGCAATAGCGGAGGGAACAAGTGAAATTATAGGGATCGAAAGATTG
AGGATTAAGGAAAGTGATAGAATTGAAAGTATAAGGAAAATCTTAGGATTATATGGTGTAGGTAGTGAAGTAAAGTATAA
TTCTATTCTGATATTCGGAATTAACAAGGGTATGTTAAACTCTCCAGTTACAGACTGTTTGAATGATCACAGAGTTGCTA
TGATGTCGTCAGCCTTAGCTTTAGTGAATGGTGGGGTAATTACATCAGCTGAATGTGTAGGTAAAAGTAATCCTAATTAC
TGGCAAGATTTATTATCACTAAATGCGAAGATTTCTATTGAATGA

Upstream 100 bases:

>100_bases
GGGCCTTCATATTTTGCAGTTTCTAAGAATGGAGAAGAAGGTCCGATATACGAAAGTCTTAAGAAATTTGGAGATGTTAT
TATAGTTAGGCCTGTAAGTC

Downstream 100 bases:

>100_bases
GACCATTAATTGTAGCTTCATTACCAATTAAAAAGATAGAAGACTTAAAACTTATAGAAAATTTTTTAGATGCAGATCTA
ATAGAACTAAGACTTGATTA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIVKIYPSKISGIIKAPQSKSLAIRLIFLSLFTRVYLHNLVLSEDVIDAIKSVRALGVKVKNNSEFIPPEKLEIKERFIK
LKGSATTLRMLIPILAAIGGEVTIDADESLRRRPLNRIVQALSNYGISFSSYSLPLTITGKLSSNEIKISGDESSQYISG
LIYALHILNGGSIEILPPISSKSYILLTIDLFKRFGSDVKFYGSKIHVNPNNLVEFQGEVAGDYGLASFYALSALVSGGG
ITITNLWEPKEYFGDHSIVKIFSEMGASSEYKDGRWFVKAKDKYSPIKIDIDDAPDLAMTIAGLSAIAEGTSEIIGIERL
RIKESDRIESIRKILGLYGVGSEVKYNSILIFGINKGMLNSPVTDCLNDHRVAMMSSALALVNGGVITSAECVGKSNPNY
WQDLLSLNAKISIE

Sequences:

>Translated_414_residues
MIVKIYPSKISGIIKAPQSKSLAIRLIFLSLFTRVYLHNLVLSEDVIDAIKSVRALGVKVKNNSEFIPPEKLEIKERFIK
LKGSATTLRMLIPILAAIGGEVTIDADESLRRRPLNRIVQALSNYGISFSSYSLPLTITGKLSSNEIKISGDESSQYISG
LIYALHILNGGSIEILPPISSKSYILLTIDLFKRFGSDVKFYGSKIHVNPNNLVEFQGEVAGDYGLASFYALSALVSGGG
ITITNLWEPKEYFGDHSIVKIFSEMGASSEYKDGRWFVKAKDKYSPIKIDIDDAPDLAMTIAGLSAIAEGTSEIIGIERL
RIKESDRIESIRKILGLYGVGSEVKYNSILIFGINKGMLNSPVTDCLNDHRVAMMSSALALVNGGVITSAECVGKSNPNY
WQDLLSLNAKISIE
>Mature_414_residues
MIVKIYPSKISGIIKAPQSKSLAIRLIFLSLFTRVYLHNLVLSEDVIDAIKSVRALGVKVKNNSEFIPPEKLEIKERFIK
LKGSATTLRMLIPILAAIGGEVTIDADESLRRRPLNRIVQALSNYGISFSSYSLPLTITGKLSSNEIKISGDESSQYISG
LIYALHILNGGSIEILPPISSKSYILLTIDLFKRFGSDVKFYGSKIHVNPNNLVEFQGEVAGDYGLASFYALSALVSGGG
ITITNLWEPKEYFGDHSIVKIFSEMGASSEYKDGRWFVKAKDKYSPIKIDIDDAPDLAMTIAGLSAIAEGTSEIIGIERL
RIKESDRIESIRKILGLYGVGSEVKYNSILIFGINKGMLNSPVTDCLNDHRVAMMSSALALVNGGVITSAECVGKSNPNY
WQDLLSLNAKISIE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=422, Percent_Identity=26.5402843601896, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_SULSO (Q980I5)

Other databases:

- EMBL:   AE006641
- PIR:   G90173
- RefSeq:   NP_341856.1
- ProteinModelPortal:   Q980I5
- GeneID:   1455456
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0309
- NMPDR:   fig|273057.1.peg.279
- HOGENOM:   HBG646626
- OMA:   QEDATEP
- ProtClustDB:   PRK02427
- BioCyc:   SSOL273057:SSO0309-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45322; Mature: 45322

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKIYPSKISGIIKAPQSKSLAIRLIFLSLFTRVYLHNLVLSEDVIDAIKSVRALGVKV
CEEEEECHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KNNSEFIPPEKLEIKERFIKLKGSATTLRMLIPILAAIGGEVTIDADESLRRRPLNRIVQ
CCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
ALSNYGISFSSYSLPLTITGKLSSNEIKISGDESSQYISGLIYALHILNGGSIEILPPIS
HHHHCCCEEECEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHEECCCCEEEECCCC
SKSYILLTIDLFKRFGSDVKFYGSKIHVNPNNLVEFQGEVAGDYGLASFYALSALVSGGG
CCCEEEEEHHHHHHHCCCEEEECCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC
ITITNLWEPKEYFGDHSIVKIFSEMGASSEYKDGRWFVKAKDKYSPIKIDIDDAPDLAMT
EEEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHH
IAGLSAIAEGTSEIIGIERLRIKESDRIESIRKILGLYGVGSEVKYNSILIFGINKGMLN
HHHHHHHHCCHHHHEEHHHEEECCHHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCCCC
SPVTDCLNDHRVAMMSSALALVNGGVITSAECVGKSNPNYWQDLLSLNAKISIE
CCHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHCCCCCCHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MIVKIYPSKISGIIKAPQSKSLAIRLIFLSLFTRVYLHNLVLSEDVIDAIKSVRALGVKV
CEEEEECHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
KNNSEFIPPEKLEIKERFIKLKGSATTLRMLIPILAAIGGEVTIDADESLRRRPLNRIVQ
CCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
ALSNYGISFSSYSLPLTITGKLSSNEIKISGDESSQYISGLIYALHILNGGSIEILPPIS
HHHHCCCEEECEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHEECCCCEEEECCCC
SKSYILLTIDLFKRFGSDVKFYGSKIHVNPNNLVEFQGEVAGDYGLASFYALSALVSGGG
CCCEEEEEHHHHHHHCCCEEEECCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC
ITITNLWEPKEYFGDHSIVKIFSEMGASSEYKDGRWFVKAKDKYSPIKIDIDDAPDLAMT
EEEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHH
IAGLSAIAEGTSEIIGIERLRIKESDRIESIRKILGLYGVGSEVKYNSILIFGINKGMLN
HHHHHHHHCCHHHHEEHHHEEECCHHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCCCC
SPVTDCLNDHRVAMMSSALALVNGGVITSAECVGKSNPNYWQDLLSLNAKISIE
CCHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHCCCCCCHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726