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The map label for this gene is cdc6-1

Identifier: 15897201

GI number: 15897201

Start: 221077

End: 222270

Strand: Reverse

Name: cdc6-1

Synonym: SSO0257

Alternate gene names: 15897201

Gene position: 222270-221077 (Counterclockwise)

Preceding gene: 15897202

Following gene: 15897200

Centisome position: 7.43

GC content: 34.84

Gene sequence:

>1194_bases
ATGAGTGATATAATTGATGAGGTCATTTCTTCATTCAAGACATCAAGCATCTTCATAAATAGGGAATATTTGTTGCCTGA
TTATATCCCAGACGAGTTACCACATAGAGAGGATCAGATAAGAAAGATTGCAAGTATTTTAGCTCCATTATATAGGGAAG
AGAAACCCAACAATATTTTCATATACGGTCTGACTGGGACGGGAAAGACAGCCGTAGTGAAGTTTGTTTTATCTAAATTA
CATAAGAAATTTCTTGGTAAATTTAAACATGTATATATTAATACTAGACAGATAGATACGCCATATAGGGTATTGGCTGA
TCTGTTGGAATCACTAGATGTAAAGGTTCCATTTACCGGGTTATCAATAGCCGAACTGTATAGACGATTGGTAAAAGCAG
TGAGAGACTACGGTTCACAAGTCGTCATAGTTTTAGATGAGATTGATGCTTTCGTTAAAAAGTATAATGATGATATTCTA
TACAAATTAAGTAGGATTAATAGTGAGGTGAACAAGAGTAAGATATCTTTTATAGGAATAACTAATGATGTTAAGTTTGT
AGATCTGTTAGATCCTAGAGTTAAAAGTAGTTTAAGTGAAGAGGAGATAATTTTCCCCCCTTATAATGCGGAAGAGTTAG
AAGATATTTTGACAAAGAGAGCACAAATGGCATTCAAGCCTGGAGTTTTACCAGATAATGTAATTAAATTATGTGCTGCA
CTAGCTGCACGAGAGCATGGTGACGCGCGTAGAGCCTTGGATCTTTTAAGAGTTTCTGGTGAAATAGCTGAAAGAATGAA
AGACACTAAGGTTAAAGAAGAGTATGTGTATATGGCTAAGGAAGAAATAGAGAGAGATCGAGTAAGAGATATTATATTAA
CTCTTCCTTTTCACTCTAAGTTAGTTCTTATGGCAGTTGTTTCTATATCCTCCGAAGAAAATGTAGTTTCAACTACTGGT
GCTGTATATGAGACTTATCTGAACATTTGTAAGAAGTTAGGTGTAGAAGCTGTTACTCAAAGAAGAGTTAGTGATATTAT
AAATGAATTAGATATGGTAGGGATACTAACAGCCAAGGTTGTTAACCGGGGTAGATATGGCAAGACTAAGGAGATAGGTT
TAGCTGTTGATAAGAATATAATTGTTAGATCTTTAATAGAAAGCGATAGTAGGTTTGCTGATCTCTGGAGTTGA

Upstream 100 bases:

>100_bases
ATATTTACCTTAAGTTCTCCAGTGGAAACAAAGGGGTTTTTTACTCCCCAGTTAAATAACATCCGTCTTAAAAGATGTAT
CAGTAAAAGTAAGTTAAGAG

Downstream 100 bases:

>100_bases
TGATGGTTACTTTCCATTATCGTATAAGGGAGGAAAAGGCAAAACTGCACTAGTTGTGGTTACTTTTTACGATTACGAGA
TTATTGATTTAGATTGGGGT

Product: cell division control 6/orc1-like protein

Products: NA

Alternate protein names: CDC6 homolog 1

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSDIIDEVISSFKTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIFIYGLTGTGKTAVVKFVLSKL
HKKFLGKFKHVYINTRQIDTPYRVLADLLESLDVKVPFTGLSIAELYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDIL
YKLSRINSEVNKSKISFIGITNDVKFVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAA
LAAREHGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSKLVLMAVVSISSEENVVSTTG
AVYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKVVNRGRYGKTKEIGLAVDKNIIVRSLIESDSRFADLWS

Sequences:

>Translated_397_residues
MSDIIDEVISSFKTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIFIYGLTGTGKTAVVKFVLSKL
HKKFLGKFKHVYINTRQIDTPYRVLADLLESLDVKVPFTGLSIAELYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDIL
YKLSRINSEVNKSKISFIGITNDVKFVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAA
LAAREHGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSKLVLMAVVSISSEENVVSTTG
AVYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKVVNRGRYGKTKEIGLAVDKNIIVRSLIESDSRFADLWS
>Mature_396_residues
SDIIDEVISSFKTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIFIYGLTGTGKTAVVKFVLSKLH
KKFLGKFKHVYINTRQIDTPYRVLADLLESLDVKVPFTGLSIAELYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDILY
KLSRINSEVNKSKISFIGITNDVKFVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAAL
AAREHGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSKLVLMAVVSISSEENVVSTTGA
VYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKVVNRGRYGKTKEIGLAVDKNIIVRSLIESDSRFADLWS

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=376, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI299890795, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI299890793, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI31795544, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17555708, Length=317, Percent_Identity=23.3438485804416, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506005, Length=295, Percent_Identity=24.7457627118644, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355681, Length=362, Percent_Identity=25.1381215469613, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137456, Length=329, Percent_Identity=26.1398176291793, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC61_SULSO (Q980N4)

Other databases:

- EMBL:   AE006641
- PIR:   E90167
- RefSeq:   NP_341806.1
- PDB:   2QBY
- PDBsum:   2QBY
- ProteinModelPortal:   Q980N4
- SMR:   Q980N4
- DIP:   DIP-48851N
- GeneID:   1455406
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0257
- NMPDR:   fig|273057.1.peg.229
- HOGENOM:   HBG553472
- OMA:   ATISFPK
- PhylomeDB:   Q980N4
- ProtClustDB:   CLSK802636
- BioCyc:   SSOL273057:SSO0257-MONOMER
- HAMAP:   MF_01407
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C

EC number: NA

Molecular weight: Translated: 45168; Mature: 45037

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIIDEVISSFKTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIF
CHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
IYGLTGTGKTAVVKFVLSKLHKKFLGKFKHVYINTRQIDTPYRVLADLLESLDVKVPFTG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCC
LSIAELYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDILYKLSRINSEVNKSKISFIGI
CCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEE
TNDVKFVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAA
CCCCEEHHHCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAAREHGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
LVLMAVVSISSEENVVSTTGAVYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRGRYGKTKEIGLAVDKNIIVRSLIESDSRFADLWS
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SDIIDEVISSFKTSSIFINREYLLPDYIPDELPHREDQIRKIASILAPLYREEKPNNIF
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
IYGLTGTGKTAVVKFVLSKLHKKFLGKFKHVYINTRQIDTPYRVLADLLESLDVKVPFTG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCC
LSIAELYRRLVKAVRDYGSQVVIVLDEIDAFVKKYNDDILYKLSRINSEVNKSKISFIGI
CCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEE
TNDVKFVDLLDPRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLPDNVIKLCAA
CCCCEEHHHCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAAREHGDARRALDLLRVSGEIAERMKDTKVKEEYVYMAKEEIERDRVRDIILTLPFHSK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
LVLMAVVSISSEENVVSTTGAVYETYLNICKKLGVEAVTQRRVSDIINELDMVGILTAKV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRGRYGKTKEIGLAVDKNIIVRSLIESDSRFADLWS
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726