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The map label for this gene is hpS-2 [H]

Identifier: 15897153

GI number: 15897153

Start: 176021

End: 176698

Strand: Direct

Name: hpS-2 [H]

Synonym: SSO0202

Alternate gene names: 15897153

Gene position: 176021-176698 (Clockwise)

Preceding gene: 15897151

Following gene: 15897154

Centisome position: 5.88

GC content: 31.56

Gene sequence:

>678_bases
ATGAGAGAGGTACTACTTGAAAAACTTCGTACTGAAAAATTTTTACAGATAGCTTTAGATTTTATAGATATCAATGATGC
AATAAAAGTGGTTAATGAAGTCAAAGATCTAGAAAATGAAATCATTGAAATAGGAACACCACTACTAAAATCATTCGGGA
TAGAAGGAATAAGAAAAATAAAATCATTAGTTCCAGATAAAATAATTGTAGCTGATACTAAAACTGCAGATGCAGGAGAT
GTTGAGGTTGAAATAGCTAAACTAGGCGGAGCTCATATAATGACGGTTTTAGGAATAATGGATGATTCAACTATTTATTC
AGCTGTAAAAAAAGCTAGGGAATTAGATATACTAGTCCAAGCTGACTTAATTAATGTTAAAAACGTATATGAAAGATCAA
AGGAGCTTAAGCAATTAGGAGTAGATATTATAGGTTTCCATGTTGGTTTAGATGTACAAAAGAGTAGAGGCATAAGTGTA
GCTGATTTAAAGAATGAGATACGAAAGGTGTCTGAGCTAAACTTAATAATATCAATAGCTGGAGGCTTAAATAAAGATAG
AATTTTAGAACTCATAGATCTGCCAGTAAGCATATATGTAGTAGGAGGAGCGATAACTAGAAGTAAAGAGCCTAAGAACG
TATCTAAAGAGATAGTTAACATATTAAAGGGTAGATAA

Upstream 100 bases:

>100_bases
TGTTTGGCACTAATATCCACAGTAATTTGCCTTTACTGCTATAAAATAAAAAGTCACTGTCAATTACTTTAAGTACTTTT
AAAGCACATATTTACCTTAA

Downstream 100 bases:

>100_bases
TAAGTATATATGGGGTTTAAATTTGTCACAACCAGGTCAACAGAAGTCTAAGGATGTAAAGATGGTATCTAAACAAGTTA
TAAGTACGAATATAATAAAC

Product: D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hpS-2)

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase; HUMPS [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MREVLLEKLRTEKFLQIALDFIDINDAIKVVNEVKDLENEIIEIGTPLLKSFGIEGIRKIKSLVPDKIIVADTKTADAGD
VEVEIAKLGGAHIMTVLGIMDDSTIYSAVKKARELDILVQADLINVKNVYERSKELKQLGVDIIGFHVGLDVQKSRGISV
ADLKNEIRKVSELNLIISIAGGLNKDRILELIDLPVSIYVVGGAITRSKEPKNVSKEIVNILKGR

Sequences:

>Translated_225_residues
MREVLLEKLRTEKFLQIALDFIDINDAIKVVNEVKDLENEIIEIGTPLLKSFGIEGIRKIKSLVPDKIIVADTKTADAGD
VEVEIAKLGGAHIMTVLGIMDDSTIYSAVKKARELDILVQADLINVKNVYERSKELKQLGVDIIGFHVGLDVQKSRGISV
ADLKNEIRKVSELNLIISIAGGLNKDRILELIDLPVSIYVVGGAITRSKEPKNVSKEIVNILKGR
>Mature_225_residues
MREVLLEKLRTEKFLQIALDFIDINDAIKVVNEVKDLENEIIEIGTPLLKSFGIEGIRKIKSLVPDKIIVADTKTADAGD
VEVEIAKLGGAHIMTVLGIMDDSTIYSAVKKARELDILVQADLINVKNVYERSKELKQLGVDIIGFHVGLDVQKSRGISV
ADLKNEIRKVSELNLIISIAGGLNKDRILELIDLPVSIYVVGGAITRSKEPKNVSKEIVNILKGR

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with hxlB, may act as a formaldehyde detoxification system [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790640, Length=206, Percent_Identity=25.7281553398058, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790006, Length=209, Percent_Identity=28.2296650717703, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017553
- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 24804; Mature: 24804

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVLLEKLRTEKFLQIALDFIDINDAIKVVNEVKDLENEIIEIGTPLLKSFGIEGIRKI
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHH
KSLVPDKIIVADTKTADAGDVEVEIAKLGGAHIMTVLGIMDDSTIYSAVKKARELDILVQ
HHHCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
ADLINVKNVYERSKELKQLGVDIIGFHVGLDVQKSRGISVADLKNEIRKVSELNLIISIA
HHHHHHHHHHHHHHHHHHHCCHHEEEEECCEEHHCCCCCHHHHHHHHHHHHHHHEEEEEC
GGLNKDRILELIDLPVSIYVVGGAITRSKEPKNVSKEIVNILKGR
CCCCHHHHHHHHCCCEEEEEECCHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MREVLLEKLRTEKFLQIALDFIDINDAIKVVNEVKDLENEIIEIGTPLLKSFGIEGIRKI
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHH
KSLVPDKIIVADTKTADAGDVEVEIAKLGGAHIMTVLGIMDDSTIYSAVKKARELDILVQ
HHHCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
ADLINVKNVYERSKELKQLGVDIIGFHVGLDVQKSRGISVADLKNEIRKVSELNLIISIA
HHHHHHHHHHHHHHHHHHHCCHHEEEEECCEEHHCCCCCHHHHHHHHHHHHHHHEEEEEC
GGLNKDRILELIDLPVSIYVVGGAITRSKEPKNVSKEIVNILKGR
CCCCHHHHHHHHCCCEEEEEECCHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377 [H]