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The map label for this gene is galE-2 [C]

Identifier: 15897116

GI number: 15897116

Start: 137128

End: 138063

Strand: Direct

Name: galE-2 [C]

Synonym: SSO0166

Alternate gene names: 15897116

Gene position: 137128-138063 (Clockwise)

Preceding gene: 15897115

Following gene: 15897121

Centisome position: 4.58

GC content: 33.33

Gene sequence:

>936_bases
ATGTACATAGTTACAGGTGGTGCTGGTTACATAGGTGGACATCTAGTCGATTATTTAATTTCAAAAAATTTAGAAGTAAT
AGTTATTGATGATTTATCTTATGGCAAATACAGAAATGAGAAGGCTAAATTTGTAATGTTTGACTTACGTCAAAACATGG
GAGAACTAGTAGAGAAACTAGAAAAAAATCCGATAATTTACCATTTAGCTGCAAATCCAGACGTAAGAACGTCTATGATA
AATGTGGAGGAGCATTTCGAAAGGGATGTCAAAGTCACGTTAAATGTAATGGAACTAGCAAGGAGAGTAGATGCAGAAAA
AGTAATCTTTACCTCATCATCTACTGTCTATGGAGAGACAAGTAAGATTCCAACTCCAGAATCAGAAGAACTTAAGCCAA
TTTCCAATTACGGATTATTTAAACTATTATGTGAGAATATAGTAAAATATTACGCAGAGCAATATGGCATAAAAAGTATC
AGCACAAGATTAGCAAACATAACTGGTGGCAGAGTAAGCCATGGAGTAGTAATTGACTTTATAAAAAAGCTTAAAGATAA
TCCAAATTTACTAGAGATCTTAGGAAATGGAAAACAAAGAAAAAGTTATCTGTATATCGATGATTTAATAGAGGCGTTCG
TAATGTTAGAGAAAAAAGTAAACCGGATTTATGACGTTTTTAACATAGGTAATAATGATTCAATTACTGTAGACGAGATT
GCTAAGATTGTTATAGATGAAATGAAATTAAGTCCAAGAATCACTTATAAGAATCCGACAGCTGATGGAAGAGGGTGGCC
AGGAGACGTAAGATTAATGTTATTAGATATCTCAAAAATATCAAGGGAAGTAGGCTGGTCACCCAAAATGAGTTCCAGAG
AAGTGATTAGACAAGCCGTAAAAGATTTGTTATATGGTTACAAGTCAGTCTATTGA

Upstream 100 bases:

>100_bases
AAAAATAATACACAACGCACTTATGGGAACGAGACAAACTAATCCTAATAAAAGTAATTAAGAACATCAAGTTTAATAAA
GGAATCCATTTCCATTACAT

Downstream 100 bases:

>100_bases
TAGATATGCTTCCTAATATCTCTCATCAATTTTAAGGAATATGTGAAAGTTATGTGAGAAGAAAATAAAAAATAAATTAC
TATAAATATTATTTTATGAT

Product: UDP-glucose 4-epimerase (galE-2)

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRNEKAKFVMFDLRQNMGELVEKLEKNPIIYHLAANPDVRTSMI
NVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTVYGETSKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSI
STRLANITGGRVSHGVVIDFIKKLKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNNDSITVDEI
AKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSSREVIRQAVKDLLYGYKSVY

Sequences:

>Translated_311_residues
MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRNEKAKFVMFDLRQNMGELVEKLEKNPIIYHLAANPDVRTSMI
NVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTVYGETSKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSI
STRLANITGGRVSHGVVIDFIKKLKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNNDSITVDEI
AKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSSREVIRQAVKDLLYGYKSVY
>Mature_311_residues
MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRNEKAKFVMFDLRQNMGELVEKLEKNPIIYHLAANPDVRTSMI
NVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTVYGETSKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSI
STRLANITGGRVSHGVVIDFIKKLKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNNDSITVDEI
AKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSSREVIRQAVKDLLYGYKSVY

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=332, Percent_Identity=28.9156626506024, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI42516563, Length=329, Percent_Identity=27.0516717325228, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1788353, Length=348, Percent_Identity=26.7241379310345, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994969, Length=327, Percent_Identity=24.1590214067278, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786974, Length=322, Percent_Identity=27.639751552795, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=29.6178343949045, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17568069, Length=309, Percent_Identity=25.8899676375405, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115532424, Length=330, Percent_Identity=23.9393939393939, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=225, Percent_Identity=30.6666666666667, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356223, Length=302, Percent_Identity=30.1324503311258, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35423; Mature: 35423

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRNEKAKFVMFDLRQNMGELVEKL
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
EKNPIIYHLAANPDVRTSMINVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTVYGET
CCCCEEEEEECCCCHHHHEECHHHHHCCCHHEEHHHHHHHHHCCCCEEEEECCCEEECCC
SKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSISTRLANITGGRVSHGVVIDF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHH
IKKLKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNNDSITVDEI
HHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
AKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSSREVIRQAV
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHH
KDLLYGYKSVY
HHHHHHHHHCC
>Mature Secondary Structure
MYIVTGGAGYIGGHLVDYLISKNLEVIVIDDLSYGKYRNEKAKFVMFDLRQNMGELVEKL
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
EKNPIIYHLAANPDVRTSMINVEEHFERDVKVTLNVMELARRVDAEKVIFTSSSTVYGET
CCCCEEEEEECCCCHHHHEECHHHHHCCCHHEEHHHHHHHHHCCCCEEEEECCCEEECCC
SKIPTPESEELKPISNYGLFKLLCENIVKYYAEQYGIKSISTRLANITGGRVSHGVVIDF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHH
IKKLKDNPNLLEILGNGKQRKSYLYIDDLIEAFVMLEKKVNRIYDVFNIGNNDSITVDEI
HHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
AKIVIDEMKLSPRITYKNPTADGRGWPGDVRLMLLDISKISREVGWSPKMSSREVIRQAV
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHH
KDLLYGYKSVY
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]