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The map label for this gene is sun-2 [H]

Identifier: 15897082

GI number: 15897082

Start: 102132

End: 103238

Strand: Reverse

Name: sun-2 [H]

Synonym: SSO0122

Alternate gene names: 15897082

Gene position: 103238-102132 (Counterclockwise)

Preceding gene: 15897083

Following gene: 15897081

Centisome position: 3.45

GC content: 31.26

Gene sequence:

>1107_bases
TTGAAGGACATAGTAAAGTTTTTGTCTACTGTGTTATATTACGTAGAACAGAAGAATTATCCTTTAGCGATAGCATTTAA
ACGAGCATATCTGCATAATAAGCCAAGGAAGATAGATTCTAACCTTTTATATGAATATAGTAAAAGACTAATATTATCGT
ATTATGCACTACCTCAAAGCAAAAGGTCGGCAAAGGTAAGATATTGGCTTAAAAATAGGGAAAATATTGAAATTAAATTT
CCTAAATGGATGGAGGATAAATTGTTTACATTATTAGATGTTAACGCTCTTAAAAGAAAATTAACTGAAAGATGGATATG
GGCACGTATAAACTTGCTTAAGACTGATATTGATAAAGTTTATAGAATGTTAGAGAGTCAAAATATAGAGTTTGAGCCCG
ATAAGGATTTTTATTATATGATCAAGATAAATAGATCTTCAGTAAGACTATCTTCTTTAAGTATAGTAAAAGACTTTAAA
TTGATACTTCATGATAAAGCTAGTTCTATAGTGGTAGAAGCACTTAAGCCGGAGATTAGTGAAAAATTAGTTGATCTCTC
TTCAGCACCTGGAATTAAAGCTTCTCTATATATGATGCTAACAGAAAATAGGGCTGAAACTTTCCTAGCCGATGTTGACT
TAAAGAGGTTATCGAAAGAGTATAATTTGCTAAAACGATGTGGAGTAGATTTGCGTAAGGTTCACATAATATATCAAGAT
TCAACAAAAAATAGCATCATAAAATCAGACAAGATACTATTAGACGCGCCGTGTTCTTCCTCTGGAATGATAAATAACGA
TCCTTCAATTTTATTGAAATTACGTAATGGCGAGAAAATAGAGAAATTCACTAAATTACAAAAATCCCTACTAAATGAGG
CTTTAAAGATTAAGTCCAACAAACTTGTGTATGCGGTATGTTCATTGTTTCCAGAGGAGGGTGAAAAAGTAATAGAAGAT
TATTATGAAATAGCTGAAAAACCATTTTCTAATTATCAATCTGGCTATTCCTTATTCAAGTCAGGGAAGAGATCTAACAG
AACCTTCCCTCATATTGATTCCACTGAGGGATTCTTTATATCAACCTTGAATTTAACTAAATTATAA

Upstream 100 bases:

>100_bases
GTTAAATCTAATATAGAGTAATCTTATGTGAGTCCTAATATTACCTTATGCCTAGTCAACGATAAGAATATTAGAAGTTA
AAGATTGTAATACACTTAAG

Downstream 100 bases:

>100_bases
ATTCACATTACACTCCGTCTTTTTATAAAATGATTAAAGAATGTATGACAATTCCAGATTTTATACTATATCAGAAATTA
GGTTTAAATTTTATTCCTAA

Product: Sun (fmu) protein (sun-2)

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKDIVKFLSTVLYYVEQKNYPLAIAFKRAYLHNKPRKIDSNLLYEYSKRLILSYYALPQSKRSAKVRYWLKNRENIEIKF
PKWMEDKLFTLLDVNALKRKLTERWIWARINLLKTDIDKVYRMLESQNIEFEPDKDFYYMIKINRSSVRLSSLSIVKDFK
LILHDKASSIVVEALKPEISEKLVDLSSAPGIKASLYMMLTENRAETFLADVDLKRLSKEYNLLKRCGVDLRKVHIIYQD
STKNSIIKSDKILLDAPCSSSGMINNDPSILLKLRNGEKIEKFTKLQKSLLNEALKIKSNKLVYAVCSLFPEEGEKVIED
YYEIAEKPFSNYQSGYSLFKSGKRSNRTFPHIDSTEGFFISTLNLTKL

Sequences:

>Translated_368_residues
MKDIVKFLSTVLYYVEQKNYPLAIAFKRAYLHNKPRKIDSNLLYEYSKRLILSYYALPQSKRSAKVRYWLKNRENIEIKF
PKWMEDKLFTLLDVNALKRKLTERWIWARINLLKTDIDKVYRMLESQNIEFEPDKDFYYMIKINRSSVRLSSLSIVKDFK
LILHDKASSIVVEALKPEISEKLVDLSSAPGIKASLYMMLTENRAETFLADVDLKRLSKEYNLLKRCGVDLRKVHIIYQD
STKNSIIKSDKILLDAPCSSSGMINNDPSILLKLRNGEKIEKFTKLQKSLLNEALKIKSNKLVYAVCSLFPEEGEKVIED
YYEIAEKPFSNYQSGYSLFKSGKRSNRTFPHIDSTEGFFISTLNLTKL
>Mature_368_residues
MKDIVKFLSTVLYYVEQKNYPLAIAFKRAYLHNKPRKIDSNLLYEYSKRLILSYYALPQSKRSAKVRYWLKNRENIEIKF
PKWMEDKLFTLLDVNALKRKLTERWIWARINLLKTDIDKVYRMLESQNIEFEPDKDFYYMIKINRSSVRLSSLSIVKDFK
LILHDKASSIVVEALKPEISEKLVDLSSAPGIKASLYMMLTENRAETFLADVDLKRLSKEYNLLKRCGVDLRKVHIIYQD
STKNSIIKSDKILLDAPCSSSGMINNDPSILLKLRNGEKIEKFTKLQKSLLNEALKIKSNKLVYAVCSLFPEEGEKVIED
YYEIAEKPFSNYQSGYSLFKSGKRSNRTFPHIDSTEGFFISTLNLTKL

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI8922322, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI23199998, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI270288818, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI76150625, Length=297, Percent_Identity=28.956228956229, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI76150623, Length=297, Percent_Identity=28.956228956229, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI270288816, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI2367212, Length=268, Percent_Identity=27.6119402985075, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081985, Length=274, Percent_Identity=23.7226277372263, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115534021, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536757, Length=303, Percent_Identity=25.7425742574257, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=280, Percent_Identity=27.5, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI22024126, Length=300, Percent_Identity=25.6666666666667, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 43017; Mature: 43017

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIVKFLSTVLYYVEQKNYPLAIAFKRAYLHNKPRKIDSNLLYEYSKRLILSYYALPQS
CHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KRSAKVRYWLKNRENIEIKFPKWMEDKLFTLLDVNALKRKLTERWIWARINLLKTDIDKV
CCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRMLESQNIEFEPDKDFYYMIKINRSSVRLSSLSIVKDFKLILHDKASSIVVEALKPEIS
HHHHHCCCCCCCCCCCEEEEEEEECCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHCHHHH
EKLVDLSSAPGIKASLYMMLTENRAETFLADVDLKRLSKEYNLLKRCGVDLRKVHIIYQD
HHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
STKNSIIKSDKILLDAPCSSSGMINNDPSILLKLRNGEKIEKFTKLQKSLLNEALKIKSN
CCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
KLVYAVCSLFPEEGEKVIEDYYEIAEKPFSNYQSGYSLFKSGKRSNRTFPHIDSTEGFFI
CCEEEHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
STLNLTKL
EEEEEECC
>Mature Secondary Structure
MKDIVKFLSTVLYYVEQKNYPLAIAFKRAYLHNKPRKIDSNLLYEYSKRLILSYYALPQS
CHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KRSAKVRYWLKNRENIEIKFPKWMEDKLFTLLDVNALKRKLTERWIWARINLLKTDIDKV
CCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRMLESQNIEFEPDKDFYYMIKINRSSVRLSSLSIVKDFKLILHDKASSIVVEALKPEIS
HHHHHCCCCCCCCCCCEEEEEEEECCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHCHHHH
EKLVDLSSAPGIKASLYMMLTENRAETFLADVDLKRLSKEYNLLKRCGVDLRKVHIIYQD
HHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
STKNSIIKSDKILLDAPCSSSGMINNDPSILLKLRNGEKIEKFTKLQKSLLNEALKIKSN
CCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
KLVYAVCSLFPEEGEKVIEDYYEIAEKPFSNYQSGYSLFKSGKRSNRTFPHIDSTEGFFI
CCEEEHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
STLNLTKL
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA