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The map label for this gene is doxB [H]

Identifier: 15897014

GI number: 15897014

Start: 38481

End: 40262

Strand: Direct

Name: doxB [H]

Synonym: SSO0044

Alternate gene names: 15897014

Gene position: 38481-40262 (Clockwise)

Preceding gene: 15897011

Following gene: 15897015

Centisome position: 1.29

GC content: 37.04

Gene sequence:

>1782_bases
TTGAGTGATATGGGATTAAAAGATGTTATTGTAGATATTTTCCAACTTGACAAAGATTGGACTACAAGAATTGTTATGGG
AATGTTAGTTTTAGGTGTAATATGGGGCTTATTAGGTGTTATTGATTCATTAATGGTTAGATTAGTTGAGGCTTCGTGGG
GACTTTCGGCTGTCTTACCTTTAACTCCTCAAGAATATTTCGCTGGTATAACATTACATGCTGAAAGGGACTTATTCGGT
TTTGCTCAACAAGTTATTTACGCAATATTTATATATTTTACAATAAAGCTTCTAAACATAGAACCTAGAGCCAAGTGGAT
GCTTAATCTCGGCTTTATTGCAGTTAATATTTCAATGATGTTTATGGAGGGACCAATTTTAATTATACCAGCAGCGGGTT
TTGATAACTACTTCTCCGCTACAATATGGTATTATCTCTCACCACTAGGAATACCGGGTTATTCTCAATATGTTGTCAGC
CCATTATTTTTCTGGGGCTGGATATTACTGGATGCTTTCACTTATATTGGTGGTTTCTGGATAGTATATCATTACTACTT
AGCTAGTAAAAATATGAAAGAAAAACTTCCAGTTCCTCTTGTTTACTTCTTAATGGTCACCTTAATGTTCATGATAGGGT
ATTCCGGTGTTACAGCTGCTGATGTATGGGATGTTTTAGCGTTCTATCACATAGTAGGATTAGATCCAATAGCAAATCAG
ATAGCGTTCTGGATATTTGGCCATGCGATAGTTTACATGGCTTGGGTCCCTGCAGTAGGTGCATTATATCTACTAATACC
AATGTTAGCTAACAAACCATTATATAGTGACAGAATGGGAAGAATATCTGCACTATTATACTTAATATTCTCTAACAATG
TTCCTATCCATCACTTATACATGGTCAATCTTCCCATAGCATTAAAGTTACTCCAAGAAGTTCTAACATATTCCGTAGTA
ATACCTTCCATGATGACATTCTTTAACTTGTGGGCAACCGCAAAGGGAGCTGATGTAAAGTGGAATATTATAACCGCCTG
GACTGTTACCTCATTCGCTGGGGCAATAGCAGCTGGTGTTACTGGTATATCTAACGCAACTATAAGCTTTGACGCAATAG
TTCATAACACGGATTGGGTTGTTGGACACTTTCATGCAATGATACTATTCTCCATAGTGCCTGCGGCATGGGCAGTATTA
TACATTATGATAACTATGATGAGTGGAAGGATATGGTTCTCTAAGGGAATGGCATGGTTACATTATATTGGTTATATGAT
AGGCACTACATTTCTAATCGTGGGATTTGAACTAATAGGATTCTACGGCGTAGTTAGGAGGGCTGAGATTTATCCTAGAG
TACCTGGGCTAATTGATGCTGAAGTAATAGCAACTGTTGGTGCAATTATAGCCGATTTAGCTACTTTAGTATGGTTCTTA
AATCTAGTATTAACTTTAGTTAAAGGGAGACTAGTAAGGCTAGAGGGACTATCATTGCCTCAAGTTGCTGGTGCAGTAGC
AATGAGTTTAGAATGGCCATCTTCAATCTCGTTTACTAGCCCAGTTTTGAAGTTTATAAAAACTCACAATACTAGCAAAA
AAGGTCTAGCGTCAACTATAGTATTAGCAATTGTTGGTGCAATACTTATCGTAGTTAGTGCTGTTCCGTTGGCTTTTGCA
GGTGATGCTTACACTCCACAAACTTGGATTTGGATTACTATTCTTACAATCGGAATTATTTTTTCAGCTATTGGTTCTCT
TAAAGGTATGAAGTCTATTTGA

Upstream 100 bases:

>100_bases
ACCTAATAAACTGAAAGAGTTACAAACCTTGTTAAAATAACCCTATAAAGAGTTTATAAGAAAAATATTTAAGTTAACAA
GAAGCTTTTAATAGTTAGAG

Downstream 100 bases:

>100_bases
GGTGATTAAAGTGGATAGGAAAGAAAAATTTGAACTTTATTGGGTTATATATGTAATTGTACTATTCGCAATAGTAATAG
GTGCGACTGCACCTGCAGTA

Product: Heme bearing subunit I of the terminal oxidase (doxB)

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MSDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLPLTPQEYFAGITLHAERDLFG
FAQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMMFMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVS
PLFFWGWILLDAFTYIGGFWIVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQ
IAFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLYMVNLPIALKLLQEVLTYSVV
IPSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGVTGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVL
YIMITMMSGRIWFSKGMAWLHYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFL
NLVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTIVLAIVGAILIVVSAVPLAFA
GDAYTPQTWIWITILTIGIIFSAIGSLKGMKSI

Sequences:

>Translated_593_residues
MSDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLPLTPQEYFAGITLHAERDLFG
FAQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMMFMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVS
PLFFWGWILLDAFTYIGGFWIVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQ
IAFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLYMVNLPIALKLLQEVLTYSVV
IPSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGVTGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVL
YIMITMMSGRIWFSKGMAWLHYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFL
NLVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTIVLAIVGAILIVVSAVPLAFA
GDAYTPQTWIWITILTIGIIFSAIGSLKGMKSI
>Mature_592_residues
SDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLPLTPQEYFAGITLHAERDLFGF
AQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMMFMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVSP
LFFWGWILLDAFTYIGGFWIVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQI
AFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLYMVNLPIALKLLQEVLTYSVVI
PSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGVTGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVLY
IMITMMSGRIWFSKGMAWLHYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFLN
LVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTIVLAIVGAILIVVSAVPLAFAG
DAYTPQTWIWITILTIGIIFSAIGSLKGMKSI

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=296, Percent_Identity=25, Blast_Score=80, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6226519, Length=272, Percent_Identity=25, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 65832; Mature: 65701

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLP
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
LTPQEYFAGITLHAERDLFGFAQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMM
CCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEE
FMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVSPLFFWGWILLDAFTYIGGFW
EECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQ
HHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHH
IAFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
MVNLPIALKLLQEVLTYSVVIPSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHH
TGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVLYIMITMMSGRIWFSKGMAWL
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTI
HHHHHHHCCCEEEECCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
VLAIVGAILIVVSAVPLAFAGDAYTPQTWIWITILTIGIIFSAIGSLKGMKSI
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDMGLKDVIVDIFQLDKDWTTRIVMGMLVLGVIWGLLGVIDSLMVRLVEASWGLSAVLP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
LTPQEYFAGITLHAERDLFGFAQQVIYAIFIYFTIKLLNIEPRAKWMLNLGFIAVNISMM
CCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEE
FMEGPILIIPAAGFDNYFSATIWYYLSPLGIPGYSQYVVSPLFFWGWILLDAFTYIGGFW
EECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYHYYLASKNMKEKLPVPLVYFLMVTLMFMIGYSGVTAADVWDVLAFYHIVGLDPIANQ
HHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHH
IAFWIFGHAIVYMAWVPAVGALYLLIPMLANKPLYSDRMGRISALLYLIFSNNVPIHHLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
MVNLPIALKLLQEVLTYSVVIPSMMTFFNLWATAKGADVKWNIITAWTVTSFAGAIAAGV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHH
TGISNATISFDAIVHNTDWVVGHFHAMILFSIVPAAWAVLYIMITMMSGRIWFSKGMAWL
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HYIGYMIGTTFLIVGFELIGFYGVVRRAEIYPRVPGLIDAEVIATVGAIIADLATLVWFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLVLTLVKGRLVRLEGLSLPQVAGAVAMSLEWPSSISFTSPVLKFIKTHNTSKKGLASTI
HHHHHHHCCCEEEECCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
VLAIVGAILIVVSAVPLAFAGDAYTPQTWIWITILTIGIIFSAIGSLKGMKSI
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]