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The map label for this gene is hsdM [C]

Identifier: 15893273

GI number: 15893273

Start: 1251643

End: 1252038

Strand: Reverse

Name: hsdM [C]

Synonym: RC1350

Alternate gene names: 15893273

Gene position: 1252038-1251643 (Counterclockwise)

Preceding gene: 15893274

Following gene: 15893272

Centisome position: 98.68

GC content: 34.09

Gene sequence:

>396_bases
TTGCCATTTTCTCAAACTATCACTAAAAAAACTAGCAAAAACGGCAAAACTATAACAGAAAATCATATAACTTCTCTTTT
TAATAACGGCATTGCAAAAAATAACGGTGATGCTGCTTGTGTTTTGCATTGCCTGCAAAATTTAAAAGAGGGTGGTAGAA
TGGCATTGGTAGTACCTGAAGGGTTCTTATTCAGAAAAGACACCGCTGCTGTTCGTCAATTTTTACTATCAAAAGCAAAG
CTGCAACTCGTTATCTCTCTACCGCAAGGTACTTTTTTACCTTATACAGGAGTAAAAACGTCAATACTTTATTTTATCGA
TGTACATAAACCGAATAATCAAAAAGAATATTGGTTTTATGAGGTTAAGAATATCGGCGTTACGTCTAGACAATAA

Upstream 100 bases:

>100_bases
ACGGACATAGCGGAATTCAGCAAATAAATAGTCTTGAGAAACCTAATGATGTTAAACCCTTAACTGATCAGCAGTTAAAG
TTTGATGTAATTGTTACTAA

Downstream 100 bases:

>100_bases
AAAAAGAAAAATTGTCGGTATAAATGATTTAAACAGGCGAGGAAATTAAATTTATCTAAAATTCCTTTTATAGATCTCGA
TTTTTATCAAATAGCTAAAA

Product: putative type I restriction enzyme M subunit

Products: S-Adenosyl-L-Homocysteine; DNA 6-Methylaminopurine. [C]

Alternate protein names: Type I Restriction- System Methyltransferase Subunit; Type I Restriction- System M Subunit; Type I Restriction M Protein; N-6 DNA Methylase Family; Type I Restriction M Subunit; Restriction- Protein; Site-Specific DNA-Methyltransferase; Type I Restriction- System DNA-Methyltransferase; Type I Restriction- System Methylation Subunit; Type I Restriction- System Subunit M; Type I Restriction EcoEI M Protein

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MPFSQTITKKTSKNGKTITENHITSLFNNGIAKNNGDAACVLHCLQNLKEGGRMALVVPEGFLFRKDTAAVRQFLLSKAK
LQLVISLPQGTFLPYTGVKTSILYFIDVHKPNNQKEYWFYEVKNIGVTSRQ

Sequences:

>Translated_131_residues
MPFSQTITKKTSKNGKTITENHITSLFNNGIAKNNGDAACVLHCLQNLKEGGRMALVVPEGFLFRKDTAAVRQFLLSKAK
LQLVISLPQGTFLPYTGVKTSILYFIDVHKPNNQKEYWFYEVKNIGVTSRQ
>Mature_130_residues
PFSQTITKKTSKNGKTITENHITSLFNNGIAKNNGDAACVLHCLQNLKEGGRMALVVPEGFLFRKDTAAVRQFLLSKAKL
QLVISLPQGTFLPYTGVKTSILYFIDVHKPNNQKEYWFYEVKNIGVTSRQ

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 14721; Mature: 14590

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSQTITKKTSKNGKTITENHITSLFNNGIAKNNGDAACVLHCLQNLKEGGRMALVVPE
CCCCHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
GFLFRKDTAAVRQFLLSKAKLQLVISLPQGTFLPYTGVKTSILYFIDVHKPNNQKEYWFY
CEEEECHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE
EVKNIGVTSRQ
EEEECCCCCCC
>Mature Secondary Structure 
PFSQTITKKTSKNGKTITENHITSLFNNGIAKNNGDAACVLHCLQNLKEGGRMALVVPE
CCCHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
GFLFRKDTAAVRQFLLSKAKLQLVISLPQGTFLPYTGVKTSILYFIDVHKPNNQKEYWFY
CEEEECHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE
EVKNIGVTSRQ
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; DNA Adenine; DNA [C]

Specific reaction: S-Adenosyl-L-Methionine + DNA Adenine = S-Adenosyl-L-Homocysteine + DNA 6-Methylaminopurine. Protein + DNA = Protein-DNA [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA