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The map label for this gene is ywlC [H]

Identifier: 15893238

GI number: 15893238

Start: 1218306

End: 1219244

Strand: Reverse

Name: ywlC [H]

Synonym: RC1315

Alternate gene names: 15893238

Gene position: 1219244-1218306 (Counterclockwise)

Preceding gene: 161723838

Following gene: 15893232

Centisome position: 96.1

GC content: 36.53

Gene sequence:

>939_bases
ATGATAAACAAAGCAGTTCAATTTATAAAATCAGGTAAAGTGGTTGTTTTTCCGACTGAAACAGTCTATGGGATTGGTGC
GGATGCCACAAATAATGAGGCGTGTTTAAAGATTTTTCAGTTCAAAGAGCGTCCTGCTATCAATCCGCTTATCGTGCATG
TCTCCTCCATAGAGCAAGCAAAGGAAATAGGGGAGTTTGACGATTTAGCTACAAAAATAGCAGAAAAATTTTGGTCTGGA
CCATTATCTATAGTTGTCCCTTTAAAAGAGAATGCAAATATTGCTCCTAGCGTAACAGCAGGACTAAATACCATAGCACT
TCGGATACCATCTTATCCTGTAGCGTTAGAGCTTATCAGACAATCAGGCATACCTATAGCTGCCCCAAGTGCTAACCCTT
CAAACTATATTAGTCCGACTAACGCTGAGCATGTCACAAAACATTTTAAGGATAATCAGGAAATTTTTATTTTAGCACCT
GAAATCTATCAATCTAAATATGGGCTAGAGTCAACGATAATTGATACAACAACTGTTACTCCTACTATTCTTAGAGAAGG
GTTTATAACTGCTGAAATTTTAGGAGAAATACTAGGGATAGAAGTTTTAAAAGCATCAGAGACAAGTACTATAAAAGCTT
CGGGAATGCTTGCAAAACACTATTCACCAAAAGTACCGGTTAGGCTAAATGCTATAAATTTAGAGGATAAAGAAATCGGA
TTAAATTTTAGCAATAGCAATCTTACAGGAAGATTTTCATTAAACTTAAGTGTAAAAGGTGACTTTATAGAAGCCGCTGC
AAATCTTTATGCTTATTTAAGAATACTTGACGATTATGCTGCATCTCATGATGTAAGAGGTATAGCAGTTAGCCCTATAC
CTCAAGTGAATATAGGGGCTGCAATTAATGATCGCCTAAAACGTGCCGCAAAATCATAA

Upstream 100 bases:

>100_bases
TACTCGTTAATGACTCTGATCCAAAGATCGCTCAAAATCGTTTGTCGTTATTACAGAATATTTGTGAATTATTTGATAAA
GTAGCTAAGTTTAACCGCTT

Downstream 100 bases:

>100_bases
ATTTCGGCGTTCTATTCGCCTTAATAGCTTTTTGATGATATTTGGTAATTACATAGTTATCGTGCGGTTTTAAATAATCA
TTTTTATTTATAATTTCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MINKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKERPAINPLIVHVSSIEQAKEIGEFDDLATKIAEKFWSG
PLSIVVPLKENANIAPSVTAGLNTIALRIPSYPVALELIRQSGIPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSKYGLESTIIDTTTVTPTILREGFITAEILGEILGIEVLKASETSTIKASGMLAKHYSPKVPVRLNAINLEDKEIG
LNFSNSNLTGRFSLNLSVKGDFIEAAANLYAYLRILDDYAASHDVRGIAVSPIPQVNIGAAINDRLKRAAKS

Sequences:

>Translated_312_residues
MINKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKERPAINPLIVHVSSIEQAKEIGEFDDLATKIAEKFWSG
PLSIVVPLKENANIAPSVTAGLNTIALRIPSYPVALELIRQSGIPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSKYGLESTIIDTTTVTPTILREGFITAEILGEILGIEVLKASETSTIKASGMLAKHYSPKVPVRLNAINLEDKEIG
LNFSNSNLTGRFSLNLSVKGDFIEAAANLYAYLRILDDYAASHDVRGIAVSPIPQVNIGAAINDRLKRAAKS
>Mature_312_residues
MINKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKERPAINPLIVHVSSIEQAKEIGEFDDLATKIAEKFWSG
PLSIVVPLKENANIAPSVTAGLNTIALRIPSYPVALELIRQSGIPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSKYGLESTIIDTTTVTPTILREGFITAEILGEILGIEVLKASETSTIKASGMLAKHYSPKVPVRLNAINLEDKEIG
LNFSNSNLTGRFSLNLSVKGDFIEAAANLYAYLRILDDYAASHDVRGIAVSPIPQVNIGAAINDRLKRAAKS

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=152, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081864, Length=189, Percent_Identity=22.7513227513227, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=250, Percent_Identity=37.6, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33815; Mature: 33815

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKERPAINPLIVHVSSIEQA
CCHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHH
KEIGEFDDLATKIAEKFWSGPLSIVVPLKENANIAPSVTAGLNTIALRIPSYPVALELIR
HHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCEEEEEECCCCHHHHHHHH
QSGIPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAPEIYQSKYGLESTIIDTTTVT
HCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHCCCCCEEEECCCCC
PTILREGFITAEILGEILGIEVLKASETSTIKASGMLAKHYSPKVPVRLNAINLEDKEIG
HHHHHCCCHHHHHHHHHHCEEEEECCCCCEEEECCEEEECCCCCCCEEEEEECCCCHHCC
LNFSNSNLTGRFSLNLSVKGDFIEAAANLYAYLRILDDYAASHDVRGIAVSPIPQVNIGA
EEECCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCH
AINDRLKRAAKS
HHHHHHHHHHCC
>Mature Secondary Structure
MINKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKERPAINPLIVHVSSIEQA
CCHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHH
KEIGEFDDLATKIAEKFWSGPLSIVVPLKENANIAPSVTAGLNTIALRIPSYPVALELIR
HHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCEEEEEECCCCHHHHHHHH
QSGIPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAPEIYQSKYGLESTIIDTTTVT
HCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHCCCCCEEEECCCCC
PTILREGFITAEILGEILGIEVLKASETSTIKASGMLAKHYSPKVPVRLNAINLEDKEIG
HHHHHCCCHHHHHHHHHHCEEEEECCCCCEEEECCEEEECCCCCCCEEEEEECCCCHHCC
LNFSNSNLTGRFSLNLSVKGDFIEAAANLYAYLRILDDYAASHDVRGIAVSPIPQVNIGA
EEECCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCH
AINDRLKRAAKS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]