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The map label for this gene is nuoG [H]

Identifier: 15893154

GI number: 15893154

Start: 1135580

End: 1137610

Strand: Reverse

Name: nuoG [H]

Synonym: RC1231

Alternate gene names: 15893154

Gene position: 1137610-1135580 (Counterclockwise)

Preceding gene: 15893155

Following gene: 15893153

Centisome position: 89.66

GC content: 37.22

Gene sequence:

>2031_bases
TTGGATAAAATAAAAATGATAAAGCTGAACGTAGACGGTTCTGAAATAGAAGTATCAGAAGGTAGCACCGTTTATCAAGC
CTGTACACAAGCAGGAAAAGAAATCCCTCATTTTTGTTATCATCAGCGTCTAAAAATTGCTGGTAATTGCCGTATGTGCT
TGGTTGAAATGGAAAAATCACCAAAGCCTATAGCTTCTTGTGCTATGCCGGTAAGTAACGGTATGGTTATTCATACCGAT
ACGCCGATGGTAAAAAAAGCACGTGAAGGGGTGATGGAGTTTTTACTGATTAACCATCCTTTAGATTGTCCTATTTGTGA
TCAGGGCGGAGAGTGTAATTTACAGGATCAGGCTTTCAGATACGGCAAAGGTACTAATAGATTCCACGAAAATAAGAGAT
CTATTAAAGATAAATATATGGGACCGTTGATTAAAACAGCGATGACTAGATGCATACAATGCACAAGATGTATTAGATTT
GCGAGCGATATAGCGGGAATAGAGGAAATAGGAGCTATTCACCGTGGAGAACACATTGAAGTAACTTCATATTTAGAGCA
AACTTTAGATTCCGAAATTTCCGGTAATATGATCGATATTTGTCCCGTCGGTGCTTTGAACTCTAAGCCTTATGCTTTTA
AAGCTCGTAAATGGGAGCTAAAACATACCGCTAGCATTGGAGTGCATGATGCCGAAGGCTCTAATATTCGTATTGATAGT
AGAGGCGATGAGGTAATGAGGATATTACCTCGTGTTAATGAAGAAATAAATGAAGAGTGGCTTTCGGATAAGAATCGTTT
TAGTTATGACGGTTTAAAATATCAGCGCTTGGATCGTCCTTATATCAGAAAAAACGGTAAGTTAGTAGAAGCTAGCTGGA
GTGAAGCTTTAAAGACAGTAGCGGATAAAATAAAATCCGTAAAACCAGAAAAGATTGTTGCTATTGCTGGTTCTCTCTCT
TCTGTCGAAGCAATGTTTATGTTAAAAACATTATTGCAAAAGCTTGGCTCTAATAATTACAGCGTTAATCAGTTTGACTA
TAAACTAGATACCATGCAGCGAGGTAATTATTTATTTAATACTACTATTGCAGGGATAGAAAAGGCTGATTTATGTCTGC
TAATCGGAGCAAATCCAAGGCAAATAGCTCCAGTATTAAATAGTAGAATAGGTATGCGAGTACGTGCCGACTCACTAAAA
GTAGCAAGAATAGGTGGGGGGCATAACCAAACCTATAAAATTCAGGATTTAGGAAGTGATATTAAGATTATTGAGGAGCT
AGCCATTGGTACTCATGAGTTTACGAAAGCCTTAAAAGCAGCAAAATATCTGATGATTATAGTAGGTGACGGTGTATATG
CAAGAGATGACGGATATGCTATATTGTCGCTTATTCATAAGATAGTGACTGAATATAATATTATGCGTGATGATTGGAAA
GGTTTTAATATATTGCATAATCACGCTTCTATAGTTGGCGGTCTTGATATTGGTTTTAATACTCCTATTAAGCTCGAAGA
GTTGGAACTCGCTTATTTACTTGGAACGGACGCCATCCCATTTGATAAGCTGAAATCGACTTTTATAATATATCAAGGAC
ATCACGGGGACGCAGGTGCTAGCAGTGCTGATGTAATTTTACCTGCGGCTGCTTATACCGAGCAGAGCGGAATTTACGTA
AATTTAGAAGGTAGACCGCAAATAGCAGAAAAAGCAGTATCGCCTGTAGGGGTAGCTAAAGAAGATATAGAAATTATTAA
AGAGCTTGCCGGTTATCTAAAAATAGATATCGGAATGGATAATTTGCAAGAAGTAAGAGTAAGACTTGCTAAAGAATATA
AGGTATTTGCTAGTATTGATAGAATTATAGAAAATAAATTTAGTAAGTTTAGCTCTAAAGATAAGTTATCAAAAGAGCCT
ATAACTGCAGAACCTATTAATTATTATATGACTGACGTGATTAGTAAAAATTCGGTCACTATGGCTAAGTGCGTTGAGGC
TAAGGAAGCAAGAGACGAGGAGGTGGCATGA

Upstream 100 bases:

>100_bases
TAGTACTATACGTTATACTCGCTGTTTGGTATATACTTCGTGTTGCCATCGGTTTTAAATATATGATAGAAGACAAAGCA
TACCCAAACCCTATGACTTA

Downstream 100 bases:

>100_bases
TGAAAAATATGCTATTCTCACCCCGTATGTCATTCCTGCAAAAGCTGGATTCTCACTTTTGCGGGAATGATATAATAAGA
GTACAACCATGCTAGAACTC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MDKIKMIKLNVDGSEIEVSEGSTVYQACTQAGKEIPHFCYHQRLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTD
TPMVKKAREGVMEFLLINHPLDCPICDQGGECNLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRF
ASDIAGIEEIGAIHRGEHIEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDS
RGDEVMRILPRVNEEINEEWLSDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWSEALKTVADKIKSVKPEKIVAIAGSLS
SVEAMFMLKTLLQKLGSNNYSVNQFDYKLDTMQRGNYLFNTTIAGIEKADLCLLIGANPRQIAPVLNSRIGMRVRADSLK
VARIGGGHNQTYKIQDLGSDIKIIEELAIGTHEFTKALKAAKYLMIIVGDGVYARDDGYAILSLIHKIVTEYNIMRDDWK
GFNILHNHASIVGGLDIGFNTPIKLEELELAYLLGTDAIPFDKLKSTFIIYQGHHGDAGASSADVILPAAAYTEQSGIYV
NLEGRPQIAEKAVSPVGVAKEDIEIIKELAGYLKIDIGMDNLQEVRVRLAKEYKVFASIDRIIENKFSKFSSKDKLSKEP
ITAEPINYYMTDVISKNSVTMAKCVEAKEARDEEVA

Sequences:

>Translated_676_residues
MDKIKMIKLNVDGSEIEVSEGSTVYQACTQAGKEIPHFCYHQRLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTD
TPMVKKAREGVMEFLLINHPLDCPICDQGGECNLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRF
ASDIAGIEEIGAIHRGEHIEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDS
RGDEVMRILPRVNEEINEEWLSDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWSEALKTVADKIKSVKPEKIVAIAGSLS
SVEAMFMLKTLLQKLGSNNYSVNQFDYKLDTMQRGNYLFNTTIAGIEKADLCLLIGANPRQIAPVLNSRIGMRVRADSLK
VARIGGGHNQTYKIQDLGSDIKIIEELAIGTHEFTKALKAAKYLMIIVGDGVYARDDGYAILSLIHKIVTEYNIMRDDWK
GFNILHNHASIVGGLDIGFNTPIKLEELELAYLLGTDAIPFDKLKSTFIIYQGHHGDAGASSADVILPAAAYTEQSGIYV
NLEGRPQIAEKAVSPVGVAKEDIEIIKELAGYLKIDIGMDNLQEVRVRLAKEYKVFASIDRIIENKFSKFSSKDKLSKEP
ITAEPINYYMTDVISKNSVTMAKCVEAKEARDEEVA
>Mature_676_residues
MDKIKMIKLNVDGSEIEVSEGSTVYQACTQAGKEIPHFCYHQRLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTD
TPMVKKAREGVMEFLLINHPLDCPICDQGGECNLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRF
ASDIAGIEEIGAIHRGEHIEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDS
RGDEVMRILPRVNEEINEEWLSDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWSEALKTVADKIKSVKPEKIVAIAGSLS
SVEAMFMLKTLLQKLGSNNYSVNQFDYKLDTMQRGNYLFNTTIAGIEKADLCLLIGANPRQIAPVLNSRIGMRVRADSLK
VARIGGGHNQTYKIQDLGSDIKIIEELAIGTHEFTKALKAAKYLMIIVGDGVYARDDGYAILSLIHKIVTEYNIMRDDWK
GFNILHNHASIVGGLDIGFNTPIKLEELELAYLLGTDAIPFDKLKSTFIIYQGHHGDAGASSADVILPAAAYTEQSGIYV
NLEGRPQIAEKAVSPVGVAKEDIEIIKELAGYLKIDIGMDNLQEVRVRLAKEYKVFASIDRIIENKFSKFSSKDKLSKEP
ITAEPINYYMTDVISKNSVTMAKCVEAKEARDEEVA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=683, Percent_Identity=49.6339677891654, Blast_Score=657, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=404, Percent_Identity=30.9405940594059, Blast_Score=221, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17565758, Length=683, Percent_Identity=44.0702781844802, Blast_Score=576, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI32566231, Length=576, Percent_Identity=47.3958333333333, Blast_Score=546, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI193209088, Length=253, Percent_Identity=56.5217391304348, Blast_Score=325, Evalue=6e-89,
Organism=Drosophila melanogaster, GI24640559, Length=692, Percent_Identity=46.5317919075145, Blast_Score=609, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24640557, Length=692, Percent_Identity=46.5317919075145, Blast_Score=609, Evalue=1e-174,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75426; Mature: 75426

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKMIKLNVDGSEIEVSEGSTVYQACTQAGKEIPHFCYHQRLKIAGNCRMCLVEMEKS
CCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHEECCCCEEEEEEECCC
PKPIASCAMPVSNGMVIHTDTPMVKKAREGVMEFLLINHPLDCPICDQGGECNLQDQAFR
CCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
YGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFASDIAGIEEIGAIHRGEHIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
VTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDS
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECEEEEEEECCEECEECCCCCEEEECC
RGDEVMRILPRVNEEINEEWLSDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWSEALKTV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHCCCCEEECCHHHHHHHH
ADKIKSVKPEKIVAIAGSLSSVEAMFMLKTLLQKLGSNNYSVNQFDYKLDTMQRGNYLFN
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEHHHHCCCEEEE
TTIAGIEKADLCLLIGANPRQIAPVLNSRIGMRVRADSLKVARIGGGHNQTYKIQDLGSD
EEECCCCCCCEEEEECCCCHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEEEHCCCCH
IKIIEELAIGTHEFTKALKAAKYLMIIVGDGVYARDDGYAILSLIHKIVTEYNIMRDDWK
HHHHHHHHCCHHHHHHHHHHCEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
GFNILHNHASIVGGLDIGFNTPIKLEELELAYLLGTDAIPFDKLKSTFIIYQGHHGDAGA
CCCEEECCHHHEECEECCCCCCCEEHHEEEEEEECCCCCCHHHCCCEEEEEECCCCCCCC
SSADVILPAAAYTEQSGIYVNLEGRPQIAEKAVSPVGVAKEDIEIIKELAGYLKIDIGMD
CCCCEEEEEHHEECCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCC
NLQEVRVRLAKEYKVFASIDRIIENKFSKFSSKDKLSKEPITAEPINYYMTDVISKNSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
MAKCVEAKEARDEEVA
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDKIKMIKLNVDGSEIEVSEGSTVYQACTQAGKEIPHFCYHQRLKIAGNCRMCLVEMEKS
CCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHEECCCCEEEEEEECCC
PKPIASCAMPVSNGMVIHTDTPMVKKAREGVMEFLLINHPLDCPICDQGGECNLQDQAFR
CCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
YGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFASDIAGIEEIGAIHRGEHIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
VTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDS
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEECEEEEEEECCEECEECCCCCEEEECC
RGDEVMRILPRVNEEINEEWLSDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWSEALKTV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCHHHCCCCEEECCHHHHHHHH
ADKIKSVKPEKIVAIAGSLSSVEAMFMLKTLLQKLGSNNYSVNQFDYKLDTMQRGNYLFN
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEHHHHCCCEEEE
TTIAGIEKADLCLLIGANPRQIAPVLNSRIGMRVRADSLKVARIGGGHNQTYKIQDLGSD
EEECCCCCCCEEEEECCCCHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEEEHCCCCH
IKIIEELAIGTHEFTKALKAAKYLMIIVGDGVYARDDGYAILSLIHKIVTEYNIMRDDWK
HHHHHHHHCCHHHHHHHHHHCEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
GFNILHNHASIVGGLDIGFNTPIKLEELELAYLLGTDAIPFDKLKSTFIIYQGHHGDAGA
CCCEEECCHHHEECEECCCCCCCEEHHEEEEEEECCCCCCHHHCCCEEEEEECCCCCCCC
SSADVILPAAAYTEQSGIYVNLEGRPQIAEKAVSPVGVAKEDIEIIKELAGYLKIDIGMD
CCCCEEEEEHHEECCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCC
NLQEVRVRLAKEYKVFASIDRIIENKFSKFSSKDKLSKEPITAEPINYYMTDVISKNSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
MAKCVEAKEARDEEVA
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]