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The map label for this gene is qacA [H]

Identifier: 15893104

GI number: 15893104

Start: 1082690

End: 1083100

Strand: Reverse

Name: qacA [H]

Synonym: RC1181

Alternate gene names: 15893104

Gene position: 1083100-1082690 (Counterclockwise)

Preceding gene: 15893107

Following gene: 15893103

Centisome position: 85.37

GC content: 32.6

Gene sequence:

>411_bases
ATGGTACCACAATTTCCGCAAACTGAATATATCGCTAAAGATAATTCATCATCTATATCTTATAAATTTAGATGGCATAT
TTTAATTATTTTAAGCATTTGCTTACTTTTGGTATCGATGGATGCTACAGTCTTGTATGCTGTTATGCCTACTATAATCC
TTGATTTAAAACCATCTAATTTACAACAATTATGGATAATCAATGCATATGCATTAGTATTATCAGGTCTTCTCATTACC
GCAGGTGCATTAGGAGATAGATTTGGTCGTAAAAGATTATTACTTTGGAGGCTTTTAGTTTTTTCCATCGCTTCAATGTT
AGTTTATGTATTTGATAGCTCATGGGGATTAGTATTATGTCGTGCTTTACTTGGGTTAGGAGGATCAGTGATGATGCCTT
CCACTTTATAA

Upstream 100 bases:

>100_bases
ACAAAAGAAATTTTAAAGCTAATTAAATTACTTGTTAACAGTCCCATAGTTCTCGAAAAAGATAGATTTAGTAAAACCCT
TATTAAATAACTTATCACAT

Downstream 100 bases:

>100_bases
TACACATGAACGTATGATCGCAATATCCGTGTGGGGAATAATGGCAACCGTAGGAGCAGCTATAGGACCAGTACTAGGAG
GAGTATTGGTTGAGCTTTTA

Product: putative multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MVPQFPQTEYIAKDNSSSISYKFRWHILIILSICLLLVSMDATVLYAVMPTIILDLKPSNLQQLWIINAYALVLSGLLIT
AGALGDRFGRKRLLLWRLLVFSIASMLVYVFDSSWGLVLCRALLGLGGSVMMPSTL

Sequences:

>Translated_136_residues
MVPQFPQTEYIAKDNSSSISYKFRWHILIILSICLLLVSMDATVLYAVMPTIILDLKPSNLQQLWIINAYALVLSGLLIT
AGALGDRFGRKRLLLWRLLVFSIASMLVYVFDSSWGLVLCRALLGLGGSVMMPSTL
>Mature_136_residues
MVPQFPQTEYIAKDNSSSISYKFRWHILIILSICLLLVSMDATVLYAVMPTIILDLKPSNLQQLWIINAYALVLSGLLIT
AGALGDRFGRKRLLLWRLLVFSIASMLVYVFDSSWGLVLCRALLGLGGSVMMPSTL

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 15166; Mature: 15166

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPQFPQTEYIAKDNSSSISYKFRWHILIILSICLLLVSMDATVLYAVMPTIILDLKPSN
CCCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQQLWIINAYALVLSGLLITAGALGDRFGRKRLLLWRLLVFSIASMLVYVFDSSWGLVLC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLGLGGSVMMPSTL
HHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVPQFPQTEYIAKDNSSSISYKFRWHILIILSICLLLVSMDATVLYAVMPTIILDLKPSN
CCCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQQLWIINAYALVLSGLLITAGALGDRFGRKRLLLWRLLVFSIASMLVYVFDSSWGLVLC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLGLGGSVMMPSTL
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]