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The map label for this gene is clpX [H]

Identifier: 15892991

GI number: 15892991

Start: 989253

End: 990530

Strand: Reverse

Name: clpX [H]

Synonym: RC1068

Alternate gene names: 15892991

Gene position: 990530-989253 (Counterclockwise)

Preceding gene: 15892992

Following gene: 15892986

Centisome position: 78.07

GC content: 34.82

Gene sequence:

>1278_bases
ATGGTAGTAGAAGCTGATAAAAAAGCATTGATTTGTTCGTTTTGTAGTAAAAAACAACATGAAGTAAAAAAACTGATAGC
AGGTCCTGCAGTATTTATTTGTGATGAATGTATAGATTTATGTACAGATATTATGAAAGAAGAAAATAAAGTTGCTTTAA
AGCAAATTACTTCTTCAATTCCAACGCCGCAAAAAATATGTGGCATTCTAAATGATTATGTAGTTGGGCAAGATCAAGCG
AAAAAGATTTTAGCAGTAGCGGTTTATAACCATTATAAGAGGCTTGAATATGTACAATCCGGCAATAATGACGTTGAGCT
TAATAAGTCGAATATCTTACTGATCGGTCCTACCGGTTCAGGAAAAACTTTACTTGCTCAAACGCTTGCTAAAATTTTAG
ACGTACCTTTTACTATGGCGGATGCTACTTCTTTAACGGAAGCCGGGTATGTCGGTGAAGATGTTGAGAATATATTACTG
CGTTTATTGATAGCATCTGAGTTTAATATAGCAAAAGCACAAAAAGGTATAATTTATATTGACGAGGTTGATAAAATTGC
CCGTAAATCGGAGAATCCTTCTATTACACGGGATGTATCGGGTGAAGGAGTACAGCAGGCATTACTTAAAATTATGGAAG
GAACAGTTGCTTCCGTGCCTCCTCAAGGCGGTAGGAAACACCCACAACAAGATTTCGTACAGTTAGATACTTCAAATATC
TTATTTATTTGTGGTGGTGCTTTTATGGGGATTGATAGCATTATAACCTCAAGAACTAATCATAGTTCTATAGGCTTTGC
AGCTAACGTAAATATAGATAAAGAGAAAAATAATAGTGAAATTCTTAAATCCCTAGAGATTGAGGATTTAACTAAATTCG
GTTTAATTCCTGAATTTATCGGTAGATTACCTATCGTTACTACTTTAGATGAGTTAGACAAAGAAGCTTTAATTACAATT
TTAACTAAGCCTAAGAACGCCATAGTAAAGCAATATCAGAAACAATTTGAGCTTGATGATGCTGAGCTTGTAATTGATTA
TTCAGCCTTAGAAACTATTGCCGAAAAAGCTCTAGCTAAAAAGACGGGAGCAAGAGGACTTCGTTCAATACTTGAGCATC
TTTTGCTTGATAGTATGTATAAAGTTGCCGAGCTAAAAAAACAGCGTGTTACTATTACAAAAGAGGTAGTTAACGGCTTA
GTCGAACCGATAATGACCTCTCTCATTTCTACAAAATCAAACAAAAAACAACCGATTATTACAGATATACCGGCGTAA

Upstream 100 bases:

>100_bases
TAAAAAATACGAAATAGTTGCAAATGAGCATAAAGATTATTATATATACGCAAGAGTACTATAGTAAGAATTGTTAAAAT
AAACATAAAAAAGAAAGTTA

Downstream 100 bases:

>100_bases
ATATTATTGCTTCTCTATGTCATTCCCGCGTAGGCGGGAATCCAGAAAAATAACTTCAATATTGATGTAAGAAGTTACAC
ATGTGATAAAGTAAACATAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSIPTPQKICGILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIASEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQPIITDIPA

Sequences:

>Translated_425_residues
MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSIPTPQKICGILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIASEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQPIITDIPA
>Mature_425_residues
MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSIPTPQKICGILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIASEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQPIITDIPA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=49.0963855421687, Blast_Score=308, Evalue=8e-84,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=63.9303482587065, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=40.9523809523809, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=308, Percent_Identity=45.4545454545455, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=308, Percent_Identity=45.4545454545455, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=38.0462724935733, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=40.5622489959839, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=408, Percent_Identity=39.4607843137255, Blast_Score=263, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=44.375, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24648291, Length=326, Percent_Identity=43.8650306748466, Blast_Score=278, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46655; Mature: 46655

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PTPQKICGILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCC
GKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIASEFNIAKAQKGIIYI
CHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
EHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHEECCCCE
LFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFI
EEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
GRLPIVTTLDELDKEALITILTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAK
CCCCHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHH
KTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGLVEPIMTSLISTKSNKKQPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDIPA
CCCCC
>Mature Secondary Structure
MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PTPQKICGILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCC
GKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIASEFNIAKAQKGIIYI
CHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
EHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHEECCCCE
LFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFI
EEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
GRLPIVTTLDELDKEALITILTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAK
CCCCHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHH
KTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGLVEPIMTSLISTKSNKKQPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDIPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA