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The map label for this gene is infC [H]

Identifier: 15892688

GI number: 15892688

Start: 729531

End: 730004

Strand: Reverse

Name: infC [H]

Synonym: RC0765

Alternate gene names: 15892688

Gene position: 730004-729531 (Counterclockwise)

Preceding gene: 15892689

Following gene: 15892687

Centisome position: 57.54

GC content: 35.86

Gene sequence:

>474_bases
GTGCGTTTAGTAGGCGAAAACGGTGAAATGCACGGCGTCGTAAATATTAGAGAAGCATTAGATATGGCGGAAAGGGCCGG
TCTTGACTTAGTCGAGATATCACCGAATGCTGTACCCCCTGTCTGTAAAATTCTAGATTTTGGTAAGTTTAAGTACGAAA
GCAAAAAACGTTTGCATGAAGCACGCAAAAAACAAAAAATCGTCGTACTTAAAGAAATGAAATTTAAACCTAATATTAGT
ATAGGTGATTTTGAAACTAAGTTAAGAAAAATAAAAGAATTTTTAAAAGACGGAGATAAAGTAAAAATTTCTTTATGGTT
TAAGGGACGAGAGATTCTTCATAAAGAGGTCGGTCAAGAACTATTTAAACGTATAGAAGTAGGGCTCGAAGGACTCGTTA
AAATCGATCAGCATGCTAAAATGGAAGGTAAGCAGATGATAATGATCGTTAGCCCTGATATTAAGGTGCAATAG

Upstream 100 bases:

>100_bases
AGTTAAATGCAATATATATTTATTTATAAACATAATACGGAGACATTTTATTTCTAAAAATAATTTTCCTAAGGCTAATA
GAGAAATCAGAGCTAGAGAA

Downstream 100 bases:

>100_bases
CTACTCAAATCGTCATTGCGCGCGAACGTAGAGAGTGTGGCAATCTCAGGAATTTTACTGTTTCATGAGGTTGCCGCGTC
GAGGCTTGGCCTCTCCTCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRLVGENGEMHGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKIVVLKEMKFKPNIS
IGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKVQ

Sequences:

>Translated_157_residues
MRLVGENGEMHGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKIVVLKEMKFKPNIS
IGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKVQ
>Mature_157_residues
MRLVGENGEMHGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKIVVLKEMKFKPNIS
IGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKVQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=153, Percent_Identity=50.3267973856209, Blast_Score=149, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18067; Mature: 18067

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGENGEMHGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHE
CCEECCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
ARKKQKIVVLKEMKFKPNISIGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQE
HHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHH
LFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKVQ
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC
>Mature Secondary Structure
MRLVGENGEMHGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHE
CCEECCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
ARKKQKIVVLKEMKFKPNISIGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQE
HHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHH
LFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKVQ
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]