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The map label for this gene is pepQ [H]

Identifier: 15892648

GI number: 15892648

Start: 696882

End: 698720

Strand: Reverse

Name: pepQ [H]

Synonym: RC0725

Alternate gene names: 15892648

Gene position: 698720-696882 (Counterclockwise)

Preceding gene: 15892649

Following gene: 15892642

Centisome position: 55.07

GC content: 34.04

Gene sequence:

>1839_bases
ATGACGGCTCAGCCAGCGGGCAAGGACATAAGAGATATAAACATGACAAAAATCCGCATTAATCTGCTTAGAAATTTATT
CACAGAATATGATATAGACGGTTATATAATTCCGTCTAACGATAAATATATGAGTGAATATGTTCCAAGCTATGCAAAGA
GACTTGAATATATAACAGGTTTTACTGGTTCAAACGGTATAGCTATTATATATAAAGATACAGCATTATTCTTTACCGAT
GGACGTTATTTAGAGCAAGCAAATAAAGAGCTGGATTTAGAGCTTTTTAAGCTTTTTGACTTAAAAGATATATCTAAGTT
TGGTAAAGATGCAAAAATAGGATATGATTCTGAATTATTTACTTATCCCACTATATCAAATTTAAAGTTCAATTTTCAGA
AGATTAATGGAAATTTAGTTGATAAGATTTGGCCAAATCAGCCGCTAGAGCCAAACTCTAAAGTTTATTTGCATGATATT
AAGTTGGCGGGCGTTAGTCATACTGATAAAATAAGTAAATGTCGTGAAATTTTTTTGGATTCCCGCTTTTGCAGGAATGA
CATAGAGGAAAGCGGGAATGAAACCGAGCAATCTGCCTTAGTCATTCTCGATAGCTCCTCCATATGTTGGTTACTAAATT
TGCGTGCCAGTGACGTTGCTTATACGCCTTTAATGTTTGCAAAAGTTATACTCACTTCTACACAATTATATTTGTTTATA
AATCCTACAAGAATCGATGCCGAAATTATTAATGCTCGTCCTGAAATAACGATTTTACCGGAAGAAGAATTTGAAAATAT
TTTAAGAGATAGCGAGAATACACATCTTTCCAAACCAGCTTATAGAATTTTTATTGATGATACTATAGCATCTGTTCATA
TAATGGACTTAGTAGCTGATAAAAAAGTACAAAAAATTACCGATCCATGCTTAATGCTTAAAGCTTGTAAGAACGATGTA
GAAATTAAGCATGCAATCGATTTGCATATTAAAGATGCAGTAGCTTTATGTGAATTTTTTGCTGATTTTTCTCAATGTCA
TCCCCGTGAAAACGGGGATCCAGAAAAACATAATAACGAATTGACCGAGTATTCCCTCGGTTTAAAGCTTACAGAGCAAC
GAGCTAAACAAGAGGGATATGTTTCGGATAGTTTTCCTGCTATTTGCGGATTTCAGGAAAATAGTGCTATTATTCATTAT
AGAGCTGACCCAAAAACTGCTAAAAAAATTGAAGGGCAGGGGATATTACTGATAGATTCCGGCGGTCAGTATCAAGGTGC
TACTACCGATATAACTAGAACAATAGTAATAGGTACACCGACAGATGAGCAGAAAAAGCGTTATACGCAAGTACTTAAAG
GACATATTGCTTTAGCTAAAGCCAAATTCCCAAAAAATATCATCGCAGGAGCTAATCTTGATATACTCGCTCGGCAATAT
TTATGGCAAGAAATGCTAGATTATCCACACGGTACAGGGCATGGGGTAGGGAGCTTCTTAAGTGTTCACGAAGGACCGCA
AAGCATAAATCTTCGTAATAAAACAATACTTAAAGCAGGTATGATCTTATCTAATGAACCGGGGTTTTATGTTCCTGGAA
AATATGGTATTAGGATTGAGAATTTGATGTATGTAAAAGAAAATAATGGATGGCTTGAGTTTGAGACCTTAAGTCTAGTG
CCTTATGCTAGTAAATTGACTGATATGACACTACTTAATATTGATGAAATAAACTATATCAAGGAATATTATAACAAAAT
TAGAGCTAAAATTTATGATTTATTATCCACGCAAGCGAGGAATTGGCTTAATAATGAAATAAATTTATATTGTAATTGA

Upstream 100 bases:

>100_bases
GCAAGGAGCGTGGCAATCCAGAAAAAATAATAAAAAAATTCTGTAAATCAGAATTTTTTAACTGGATTGCTTCGTCAATT
ACTTAAGTAATTTCCTTGCA

Downstream 100 bases:

>100_bases
CGTTTCCGTTATTTATTGGTATAAAGTCTATACATTTCTAATTTTCTACATTGGGACGTCGCCAAGTGGTAAGGCAACGG
TTTTTGGTATCGTCATCGGA

Product: putative aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MTAQPAGKDIRDINMTKIRINLLRNLFTEYDIDGYIIPSNDKYMSEYVPSYAKRLEYITGFTGSNGIAIIYKDTALFFTD
GRYLEQANKELDLELFKLFDLKDISKFGKDAKIGYDSELFTYPTISNLKFNFQKINGNLVDKIWPNQPLEPNSKVYLHDI
KLAGVSHTDKISKCREIFLDSRFCRNDIEESGNETEQSALVILDSSSICWLLNLRASDVAYTPLMFAKVILTSTQLYLFI
NPTRIDAEIINARPEITILPEEEFENILRDSENTHLSKPAYRIFIDDTIASVHIMDLVADKKVQKITDPCLMLKACKNDV
EIKHAIDLHIKDAVALCEFFADFSQCHPRENGDPEKHNNELTEYSLGLKLTEQRAKQEGYVSDSFPAICGFQENSAIIHY
RADPKTAKKIEGQGILLIDSGGQYQGATTDITRTIVIGTPTDEQKKRYTQVLKGHIALAKAKFPKNIIAGANLDILARQY
LWQEMLDYPHGTGHGVGSFLSVHEGPQSINLRNKTILKAGMILSNEPGFYVPGKYGIRIENLMYVKENNGWLEFETLSLV
PYASKLTDMTLLNIDEINYIKEYYNKIRAKIYDLLSTQARNWLNNEINLYCN

Sequences:

>Translated_612_residues
MTAQPAGKDIRDINMTKIRINLLRNLFTEYDIDGYIIPSNDKYMSEYVPSYAKRLEYITGFTGSNGIAIIYKDTALFFTD
GRYLEQANKELDLELFKLFDLKDISKFGKDAKIGYDSELFTYPTISNLKFNFQKINGNLVDKIWPNQPLEPNSKVYLHDI
KLAGVSHTDKISKCREIFLDSRFCRNDIEESGNETEQSALVILDSSSICWLLNLRASDVAYTPLMFAKVILTSTQLYLFI
NPTRIDAEIINARPEITILPEEEFENILRDSENTHLSKPAYRIFIDDTIASVHIMDLVADKKVQKITDPCLMLKACKNDV
EIKHAIDLHIKDAVALCEFFADFSQCHPRENGDPEKHNNELTEYSLGLKLTEQRAKQEGYVSDSFPAICGFQENSAIIHY
RADPKTAKKIEGQGILLIDSGGQYQGATTDITRTIVIGTPTDEQKKRYTQVLKGHIALAKAKFPKNIIAGANLDILARQY
LWQEMLDYPHGTGHGVGSFLSVHEGPQSINLRNKTILKAGMILSNEPGFYVPGKYGIRIENLMYVKENNGWLEFETLSLV
PYASKLTDMTLLNIDEINYIKEYYNKIRAKIYDLLSTQARNWLNNEINLYCN
>Mature_611_residues
TAQPAGKDIRDINMTKIRINLLRNLFTEYDIDGYIIPSNDKYMSEYVPSYAKRLEYITGFTGSNGIAIIYKDTALFFTDG
RYLEQANKELDLELFKLFDLKDISKFGKDAKIGYDSELFTYPTISNLKFNFQKINGNLVDKIWPNQPLEPNSKVYLHDIK
LAGVSHTDKISKCREIFLDSRFCRNDIEESGNETEQSALVILDSSSICWLLNLRASDVAYTPLMFAKVILTSTQLYLFIN
PTRIDAEIINARPEITILPEEEFENILRDSENTHLSKPAYRIFIDDTIASVHIMDLVADKKVQKITDPCLMLKACKNDVE
IKHAIDLHIKDAVALCEFFADFSQCHPRENGDPEKHNNELTEYSLGLKLTEQRAKQEGYVSDSFPAICGFQENSAIIHYR
ADPKTAKKIEGQGILLIDSGGQYQGATTDITRTIVIGTPTDEQKKRYTQVLKGHIALAKAKFPKNIIAGANLDILARQYL
WQEMLDYPHGTGHGVGSFLSVHEGPQSINLRNKTILKAGMILSNEPGFYVPGKYGIRIENLMYVKENNGWLEFETLSLVP
YASKLTDMTLLNIDEINYIKEYYNKIRAKIYDLLSTQARNWLNNEINLYCN

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=641, Percent_Identity=34.6333853354134, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI93141226, Length=621, Percent_Identity=30.7568438003221, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI264681565, Length=641, Percent_Identity=33.5413416536661, Blast_Score=285, Evalue=1e-76,
Organism=Escherichia coli, GI1788728, Length=199, Percent_Identity=29.6482412060301, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=607, Percent_Identity=30.8072487644152, Blast_Score=278, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI25149105, Length=606, Percent_Identity=28.0528052805281, Blast_Score=242, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6322999, Length=664, Percent_Identity=34.0361445783133, Blast_Score=310, Evalue=6e-85,
Organism=Drosophila melanogaster, GI17137632, Length=632, Percent_Identity=33.2278481012658, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI161078230, Length=614, Percent_Identity=28.9902280130293, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21357287, Length=614, Percent_Identity=28.9902280130293, Blast_Score=246, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 69731; Mature: 69600

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQPAGKDIRDINMTKIRINLLRNLFTEYDIDGYIIPSNDKYMSEYVPSYAKRLEYITG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCC
FTGSNGIAIIYKDTALFFTDGRYLEQANKELDLELFKLFDLKDISKFGKDAKIGYDSELF
CCCCCCEEEEEECEEEEEECCHHHHHCCCCCCCHHHHHHCHHHHHHCCCCCCCCCCCCEE
TYPTISNLKFNFQKINGNLVDKIWPNQPLEPNSKVYLHDIKLAGVSHTDKISKCREIFLD
ECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHC
SRFCRNDIEESGNETEQSALVILDSSSICWLLNLRASDVAYTPLMFAKVILTSTQLYLFI
CHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
NPTRIDAEIINARPEITILPEEEFENILRDSENTHLSKPAYRIFIDDTIASVHIMDLVAD
CCCEECHHEECCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
KKVQKITDPCLMLKACKNDVEIKHAIDLHIKDAVALCEFFADFSQCHPRENGDPEKHNNE
HHHHHHCCHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LTEYSLGLKLTEQRAKQEGYVSDSFPAICGFQENSAIIHYRADPKTAKKIEGQGILLIDS
CHHEECCEEEHHHHHHHCCCCCCCCCEEECCCCCCEEEEEECCCCHHHHCCCCEEEEEEC
GGQYQGATTDITRTIVIGTPTDEQKKRYTQVLKGHIALAKAKFPKNIIAGANLDILARQY
CCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEHHCCCCHHCCCCCHHHHHHHH
LWQEMLDYPHGTGHGVGSFLSVHEGPQSINLRNKTILKAGMILSNEPGFYVPGKYGIRIE
HHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCEEEE
NLMYVKENNGWLEFETLSLVPYASKLTDMTLLNIDEINYIKEYYNKIRAKIYDLLSTQAR
EEEEEEECCCEEEEEEEEECCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLNNEINLYCN
HHCCCCEEEEEC
>Mature Secondary Structure 
TAQPAGKDIRDINMTKIRINLLRNLFTEYDIDGYIIPSNDKYMSEYVPSYAKRLEYITG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCC
FTGSNGIAIIYKDTALFFTDGRYLEQANKELDLELFKLFDLKDISKFGKDAKIGYDSELF
CCCCCCEEEEEECEEEEEECCHHHHHCCCCCCCHHHHHHCHHHHHHCCCCCCCCCCCCEE
TYPTISNLKFNFQKINGNLVDKIWPNQPLEPNSKVYLHDIKLAGVSHTDKISKCREIFLD
ECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHC
SRFCRNDIEESGNETEQSALVILDSSSICWLLNLRASDVAYTPLMFAKVILTSTQLYLFI
CHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
NPTRIDAEIINARPEITILPEEEFENILRDSENTHLSKPAYRIFIDDTIASVHIMDLVAD
CCCEECHHEECCCCCEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
KKVQKITDPCLMLKACKNDVEIKHAIDLHIKDAVALCEFFADFSQCHPRENGDPEKHNNE
HHHHHHCCHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LTEYSLGLKLTEQRAKQEGYVSDSFPAICGFQENSAIIHYRADPKTAKKIEGQGILLIDS
CHHEECCEEEHHHHHHHCCCCCCCCCEEECCCCCCEEEEEECCCCHHHHCCCCEEEEEEC
GGQYQGATTDITRTIVIGTPTDEQKKRYTQVLKGHIALAKAKFPKNIIAGANLDILARQY
CCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEHHCCCCHHCCCCCHHHHHHHH
LWQEMLDYPHGTGHGVGSFLSVHEGPQSINLRNKTILKAGMILSNEPGFYVPGKYGIRIE
HHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCEEEE
NLMYVKENNGWLEFETLSLVPYASKLTDMTLLNIDEINYIKEYYNKIRAKIYDLLSTQAR
EEEEEEECCCEEEEEEEEECCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLNNEINLYCN
HHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]