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The map label for this gene is glmU [H]

Identifier: 15892603

GI number: 15892603

Start: 659867

End: 660613

Strand: Reverse

Name: glmU [H]

Synonym: RC0680

Alternate gene names: 15892603

Gene position: 660613-659867 (Counterclockwise)

Preceding gene: 161723846

Following gene: 15892602

Centisome position: 52.07

GC content: 30.25

Gene sequence:

>747_bases
ATGACTTATAACGATGCAAATTATCAAATAATTATTTTAGCAGCCGGTAAAGGTACTAGAATGGAGTCCGATTTACCGAA
AGTAATGCATAAAGTCGGTGGAGTTCCAATGCTTGAAACGGTATTAAAGAATTCGCTTAACGTTACAAATGATGTAATTA
TAGTGTATTCAGAAGAACTTAAAAAACATTTAACGCCCTATGCAAATATGTGTCGCTTTGTACTGCAAGAAGAACCTAAA
GGCACAGCTCATGCTACTTATGCAGCAATAGATTTAATTAATAAAAATAAAATAATATTAGTTTTATACGCTGATCATCC
TCTTATTACTCCAAAACTTATGCATGAATTAATAGCTTATTTAAGCCTTACTAATTCTGCATTAGTGACTTTAAGCTTTG
AGAGAGCAAATCCGGTTCAATATGGGAGAATAGCTACTGATAAAAATGGTGAATTTTTAGAGATAATCGAACACAAAAAT
GCAAGCGCAGAAGAGAAAAACATAAAGCTTTGTAATTCAGGTATTATGGCTTTCAGTAGCGAAATTTTAAATAAATACTT
ACCTTTATTTGCTACTAATACTAACGGTCATAAGGAAGTTTATTTAACTGAAATAGTAAAAATATGTAAAAATCACGGTG
AAAAAGTTTCATATTTATTATCTACTGATCATGATTTAATTGTTGGTGTTAATACTAAAAATGAGCTAGAAGAAGCTAAT
AATATTTTTGCTCAGAATAAGTCTTAG

Upstream 100 bases:

>100_bases
TAAAGCTTGTGGAAGTTTTAGAAGAAAGCGATGATGTGCAAAGAGTTTTTGGGAATTATGAGTTATCTGATGATGTTTAC
GAAATAATACAAGGAGAACC

Downstream 100 bases:

>100_bases
CTTTGTCGTATGGATACCCGAGTCATCATTGCAAGCGACTAAGGGCTTTGTGGCATAGATTGTTTTATGTCATTCCGGCG
AGAAACCGGGAATCCAGTAA

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTYNDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEELKKHLTPYANMCRFVLQEEPK
GTAHATYAAIDLINKNKIILVLYADHPLITPKLMHELIAYLSLTNSALVTLSFERANPVQYGRIATDKNGEFLEIIEHKN
ASAEEKNIKLCNSGIMAFSSEILNKYLPLFATNTNGHKEVYLTEIVKICKNHGEKVSYLLSTDHDLIVGVNTKNELEEAN
NIFAQNKS

Sequences:

>Translated_248_residues
MTYNDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEELKKHLTPYANMCRFVLQEEPK
GTAHATYAAIDLINKNKIILVLYADHPLITPKLMHELIAYLSLTNSALVTLSFERANPVQYGRIATDKNGEFLEIIEHKN
ASAEEKNIKLCNSGIMAFSSEILNKYLPLFATNTNGHKEVYLTEIVKICKNHGEKVSYLLSTDHDLIVGVNTKNELEEAN
NIFAQNKS
>Mature_247_residues
TYNDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEELKKHLTPYANMCRFVLQEEPKG
TAHATYAAIDLINKNKIILVLYADHPLITPKLMHELIAYLSLTNSALVTLSFERANPVQYGRIATDKNGEFLEIIEHKNA
SAEEKNIKLCNSGIMAFSSEILNKYLPLFATNTNGHKEVYLTEIVKICKNHGEKVSYLLSTDHDLIVGVNTKNELEEANN
IFAQNKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=243, Percent_Identity=32.5102880658436, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 27750; Mature: 27619

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEEL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEHHH
KKHLTPYANMCRFVLQEEPKGTAHATYAAIDLINKNKIILVLYADHPLITPKLMHELIAY
HHHCCCHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
LSLTNSALVTLSFERANPVQYGRIATDKNGEFLEIIEHKNASAEEKNIKLCNSGIMAFSS
HHHCCCEEEEEEECCCCCCEECEEEECCCCCEEEEEECCCCCCCCCCCEECCCCHHHHHH
EILNKYLPLFATNTNGHKEVYLTEIVKICKNHGEKVSYLLSTDHDLIVGVNTKNELEEAN
HHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHHHHHHH
NIFAQNKS
HHHCCCCC
>Mature Secondary Structure 
TYNDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEEL
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEHHH
KKHLTPYANMCRFVLQEEPKGTAHATYAAIDLINKNKIILVLYADHPLITPKLMHELIAY
HHHCCCHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
LSLTNSALVTLSFERANPVQYGRIATDKNGEFLEIIEHKNASAEEKNIKLCNSGIMAFSS
HHHCCCEEEEEEECCCCCCEECEEEECCCCCEEEEEECCCCCCCCCCCEECCCCHHHHHH
EILNKYLPLFATNTNGHKEVYLTEIVKICKNHGEKVSYLLSTDHDLIVGVNTKNELEEAN
HHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHHHHHHH
NIFAQNKS
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA