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The map label for this gene is ppnK [H]

Identifier: 15892535

GI number: 15892535

Start: 596487

End: 597254

Strand: Reverse

Name: ppnK [H]

Synonym: RC0612

Alternate gene names: 15892535

Gene position: 597254-596487 (Counterclockwise)

Preceding gene: 15892537

Following gene: 15892534

Centisome position: 47.07

GC content: 35.03

Gene sequence:

>768_bases
ATGAATATAAATAAAATAGCATTGATTTATAACCACAATTCCAAACATTTAGCTATTATAGAGGAAATAAAAAAACTCTA
TAATTATTGTAAAATAGAGGAAGCGGAGGTCATTATCGTAATAGGCGGGGATGGAGAATTACTACATAATATTCACCGCT
ATATGCATCTTAATATACCTTTTTACGGAGTTAATTTAGGAAGCCTCGGCTTTTTAATGAATCCTTTAGATACCAAAAAA
TTATTACAAAATATACACGAAAGTACGGTTTCTATCCTAAATCCTCTTCTTATGCAAGTCGAAGATACGAGCGGTCAAAT
ATATACGGCACTTGCTATTAACGAAGTATCGATATTTCGTAAAACTAATCAAGCTGCTAAATTTAGAATAGAAGTAAACG
GGATAGAGAGAATGAGCGAATTAGTAGCAGACGGAGCTTTAGTTGCAACACCTGCCGGAAGTAGTGCTTATAATTTATCT
GCCAGCGGTCCTATTTTACCGCTTGAGTCAAACATGTTATGCCTAACCCCTATCTGCTCATTTAGACCGCGTAGATGGCA
CGGTGCTTTACTGCTTGCATCTGCTACGATTAAATTTGAAATACTTAATACAAATAAACGACCGGTAAATGCTACTGCCG
ACTTTCAGGAGTTTAATAATATCACAAATGTTACCGTTAAATCTACTAAGGATAAGCCTGTCAAACTGCTCTTTAATAAA
AACCATACGCTGGAAGATAGAATTATTAAAGAGCAATTTGGTGGGTAA

Upstream 100 bases:

>100_bases
TTGAATGATGACATAATTTAACTTAATATTTATTTTATTATTTTATTCTTATAACTTATTATTAGTTAAGCGTCTATATA
TTAAAAAAGAAATTCATATA

Downstream 100 bases:

>100_bases
TTATTAAAAAATATTAATAATTTTTTGACTAAGAATTAAACTAATGTATGATGCCTTGTTAAAAATAACTAGGCATCATA
TATGAAATCAAGTCTTCTAT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIPFYGVNLGSLGFLMNPLDTKK
LLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFRKTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLS
ASGPILPLESNMLCLTPICSFRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNK
NHTLEDRIIKEQFGG

Sequences:

>Translated_255_residues
MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIPFYGVNLGSLGFLMNPLDTKK
LLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFRKTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLS
ASGPILPLESNMLCLTPICSFRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNK
NHTLEDRIIKEQFGG
>Mature_255_residues
MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIPFYGVNLGSLGFLMNPLDTKK
LLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFRKTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLS
ASGPILPLESNMLCLTPICSFRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNK
NHTLEDRIIKEQFGG

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=149, Percent_Identity=32.2147651006711, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325068, Length=194, Percent_Identity=30.9278350515464, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 28501; Mature: 28501

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIP
CCCEEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHEEEECCC
FYGVNLGSLGFLMNPLDTKKLLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFR
EEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEHEEEEE
KTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLSASGPILPLESNMLCLTPICS
ECCCCEEEEEEECHHHHHHHHHHCCCEEEECCCCCEEEECCCCCEEECCCCCEEEECHHC
FRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNK
CCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCEEEEECC
NHTLEDRIIKEQFGG
CCCHHHHHHHHHCCC
>Mature Secondary Structure
MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIP
CCCEEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHEEEECCC
FYGVNLGSLGFLMNPLDTKKLLQNIHESTVSILNPLLMQVEDTSGQIYTALAINEVSIFR
EEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEHEEEEE
KTNQAAKFRIEVNGIERMSELVADGALVATPAGSSAYNLSASGPILPLESNMLCLTPICS
ECCCCEEEEEEECHHHHHHHHHHCCCEEEECCCCCEEEECCCCCEEECCCCCEEEECHHC
FRPRRWHGALLLASATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNK
CCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCEEEEECC
NHTLEDRIIKEQFGG
CCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA