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The map label for this gene is cdsA

Identifier: 15892512

GI number: 15892512

Start: 577376

End: 578068

Strand: Reverse

Name: cdsA

Synonym: RC0589

Alternate gene names: 15892512

Gene position: 578068-577376 (Counterclockwise)

Preceding gene: 15892513

Following gene: 15892511

Centisome position: 45.56

GC content: 29.0

Gene sequence:

>693_bases
ATGATTACTCAAAAAGGAAAAGAACATTTGGTAAAAGATAAACAAAAATCAAACATATATTTAAGAATCCTGTCCGGTAT
AGTTTTAGTTCCGTTATTTGTCATAGCTATATTATGGTGTAAGCCTTTATTCTATATTCTAATGATATTAGTAGGTACGG
GAATGTTAAGTGAATGGTATAATATGACCTACTCTTCTATTCCTGATCTATTAATCGGGCTAATTATTATTCCGATTCCT
ATAAGCCTATTAATATTTTTAAGTATGGAAGATACCAATAGATGGCTTATTATGCTTTATTTTTGCATAATGTGGTCGGT
AGATACTTTCGCTATGATTGGCGGCAAAACTTTTAAAGGAGCAAAACTTGCTCCAAAACTTAGTCCTAAAAAAACCTGGA
GCGGTTTAGTGACGGGAGTATTATCAGCAGGTTTAGTTGCGGTATTAGTTAGTTTTATACCAAACTTTCATATTGAAAAT
TACTATTTTTCAAATAAAATTTATTTGTTTATAATTAGTTGTATATTAGCATTAATAGCTCAATTAAGTGATTTATTTAT
TTCATATTTTAAGCGAAAATTTAATATTAAAGATAGCGGTCATATAATACCCGGTCATGGAGGAGTGCTAGACAGATTTG
ATAGTATTATTTTAACCACTCTGATATTATTTCTTATGAAGATATATTTATGA

Upstream 100 bases:

>100_bases
ATCAGTAATTTCTTGCTTTGGCAAGCAGCTTATGCTGAATTATATTTCTCACCCAAATATTGGCCTGATTTTAATAAATA
TGATATACAAGAAGCTATAA

Downstream 100 bases:

>100_bases
TAATACATTTAAATAATCATGCTAAAAAAATAATTTTAAATATCGTTTTAGCTTTACTGCTTGGATATTTTGTTTTTCAT
TGCATATATGGTAACAAAGG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MITQKGKEHLVKDKQKSNIYLRILSGIVLVPLFVIAILWCKPLFYILMILVGTGMLSEWYNMTYSSIPDLLIGLIIIPIP
ISLLIFLSMEDTNRWLIMLYFCIMWSVDTFAMIGGKTFKGAKLAPKLSPKKTWSGLVTGVLSAGLVAVLVSFIPNFHIEN
YYFSNKIYLFIISCILALIAQLSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTTLILFLMKIYL

Sequences:

>Translated_230_residues
MITQKGKEHLVKDKQKSNIYLRILSGIVLVPLFVIAILWCKPLFYILMILVGTGMLSEWYNMTYSSIPDLLIGLIIIPIP
ISLLIFLSMEDTNRWLIMLYFCIMWSVDTFAMIGGKTFKGAKLAPKLSPKKTWSGLVTGVLSAGLVAVLVSFIPNFHIEN
YYFSNKIYLFIISCILALIAQLSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTTLILFLMKIYL
>Mature_230_residues
MITQKGKEHLVKDKQKSNIYLRILSGIVLVPLFVIAILWCKPLFYILMILVGTGMLSEWYNMTYSSIPDLLIGLIIIPIP
ISLLIFLSMEDTNRWLIMLYFCIMWSVDTFAMIGGKTFKGAKLAPKLSPKKTWSGLVTGVLSAGLVAVLVSFIPNFHIEN
YYFSNKIYLFIISCILALIAQLSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTTLILFLMKIYL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=177, Percent_Identity=37.2881355932203, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787677, Length=121, Percent_Identity=31.404958677686, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_RICCN (Q92I31)

Other databases:

- EMBL:   AE006914
- PIR:   E97773
- RefSeq:   NP_360226.1
- GeneID:   927687
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0589
- NMPDR:   fig|272944.1.peg.589
- OMA:   LSEWYNM
- ProtClustDB:   CLSK870917
- BioCyc:   RCON272944:RC0589-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 26126; Mature: 26126

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc4a7a58)-; HASH(0xcba44cc)-; HASH(0xcfecc9c)-; HASH(0xcda8dd0)-; HASH(0xcb69638)-; HASH(0xb53397c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITQKGKEHLVKDKQKSNIYLRILSGIVLVPLFVIAILWCKPLFYILMILVGTGMLSEWY
CCCCCCHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NMTYSSIPDLLIGLIIIPIPISLLIFLSMEDTNRWLIMLYFCIMWSVDTFAMIGGKTFKG
HCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKLAPKLSPKKTWSGLVTGVLSAGLVAVLVSFIPNFHIENYYFSNKIYLFIISCILALIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHH
QLSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTTLILFLMKIYL
HHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MITQKGKEHLVKDKQKSNIYLRILSGIVLVPLFVIAILWCKPLFYILMILVGTGMLSEWY
CCCCCCHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NMTYSSIPDLLIGLIIIPIPISLLIFLSMEDTNRWLIMLYFCIMWSVDTFAMIGGKTFKG
HCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKLAPKLSPKKTWSGLVTGVLSAGLVAVLVSFIPNFHIENYYFSNKIYLFIISCILALIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHH
QLSDLFISYFKRKFNIKDSGHIIPGHGGVLDRFDSIILTTLILFLMKIYL
HHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893