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The map label for this gene is pkcI [C]

Identifier: 15892354

GI number: 15892354

Start: 428784

End: 429146

Strand: Reverse

Name: pkcI [C]

Synonym: RC0431

Alternate gene names: 15892354

Gene position: 429146-428784 (Counterclockwise)

Preceding gene: 15892355

Following gene: 15892353

Centisome position: 33.82

GC content: 29.75

Gene sequence:

>363_bases
ATGATGTATAACAAAGAAAATGTTTTTGCAAAAATCATAGATAAAAATCTTCCGGCAGAAATAATTTATGAAGACGAACA
AATTTTAGCATTCAAAGATATAGCACCCGTAGCACCTGTACATATTATCGTTATACCTAAAAACGAATATATAGATTATG
CCGATTTCATCTCTAAAGCTTCTATAGACGAAATAAAACATTTTTTTGCTAAACTTTCTGATATAGCAAATGAAGCGGGT
TTAGATAAAGACGGTTATCGTTTAATAACTAATAAAGGCGAGAAATCGGGACAAACTATTTTTCATTTCCATTTCCATAT
TATCGGAGGTGAAAAACTCATCGGATTAATAAATAATGACTAA

Upstream 100 bases:

>100_bases
AAATTAGCATTTCTTACTGGATTGCTTCGTCAAAACTTACATTTTTTACTCGCAATGACGGAAAATTAAGCCATACAATA
AAGCTTTTAACAGGAATAAA

Downstream 100 bases:

>100_bases
AAAATACAATATTGCAGTAATCGGAGCTACAGGAAATGTAGGGCGTGAAACTCTAAATATTTTAGCTGAGCGTAATTTCC
CCATTAATAAAGTTTATGCT

Product: protein kinase C inhibitor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MMYNKENVFAKIIDKNLPAEIIYEDEQILAFKDIAPVAPVHIIVIPKNEYIDYADFISKASIDEIKHFFAKLSDIANEAG
LDKDGYRLITNKGEKSGQTIFHFHFHIIGGEKLIGLINND

Sequences:

>Translated_120_residues
MMYNKENVFAKIIDKNLPAEIIYEDEQILAFKDIAPVAPVHIIVIPKNEYIDYADFISKASIDEIKHFFAKLSDIANEAG
LDKDGYRLITNKGEKSGQTIFHFHFHIIGGEKLIGLINND
>Mature_120_residues
MMYNKENVFAKIIDKNLPAEIIYEDEQILAFKDIAPVAPVHIIVIPKNEYIDYADFISKASIDEIKHFFAKLSDIANEAG
LDKDGYRLITNKGEKSGQTIFHFHFHIIGGEKLIGLINND

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=110, Percent_Identity=41.8181818181818, Blast_Score=97, Evalue=4e-21,
Organism=Homo sapiens, GI4885413, Length=114, Percent_Identity=39.4736842105263, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787346, Length=109, Percent_Identity=36.697247706422, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=38.8888888888889, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574010, Length=110, Percent_Identity=34.5454545454545, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24581222, Length=110, Percent_Identity=34.5454545454545, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 13637; Mature: 13637

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYNKENVFAKIIDKNLPAEIIYEDEQILAFKDIAPVAPVHIIVIPKNEYIDYADFISKA
CCCCCHHHHHEECCCCCCEEEEECCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHC
SIDEIKHFFAKLSDIANEAGLDKDGYRLITNKGEKSGQTIFHFHFHIIGGEKLIGLINND
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MMYNKENVFAKIIDKNLPAEIIYEDEQILAFKDIAPVAPVHIIVIPKNEYIDYADFISKA
CCCCCHHHHHEECCCCCCEEEEECCCEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHC
SIDEIKHFFAKLSDIANEAGLDKDGYRLITNKGEKSGQTIFHFHFHIIGGEKLIGLINND
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]