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The map label for this gene is rodA [H]

Identifier: 15892299

GI number: 15892299

Start: 375967

End: 377067

Strand: Reverse

Name: rodA [H]

Synonym: RC0376

Alternate gene names: 15892299

Gene position: 377067-375967 (Counterclockwise)

Preceding gene: 15892300

Following gene: 15892298

Centisome position: 29.72

GC content: 33.7

Gene sequence:

>1101_bases
ATGCATAAAAATTATCTAGAACAATTACAAAAATTACCGATTACTTTAATTTTACTAATTAGCTTAATTTGCTGTATTGG
TTTCATTGTGCTTTATTCTGCAGCAAATAGTAATTTGCAGCCCTGGGCTTATAAACAAATTATAAATTTTTGTATATTCT
TGCCTTTAGCTATTATTATTGCATTAATTGATTTACGCATAATATTTAGGTTATCGTATATCTTTTATTTGTGCGTACTC
GCTTTACTAGTAGCCGTGGAGCTTTTCGGCTCAACTGCCATGGGCGGTAAAAGATGGATTGATATCGGTATAGTTAAGCT
TCAACCTTCCGAACCAATAAAAATCGCCGTTGTACTAATGCTTGCTAGATATTTCCATTCACTAACAATTTATGATCTTA
CAAAATTTCATAAAGTTATTATACCGATTATAGGAGTTTTAATACCGGCTTTTCTAATAATTAGAGAACCAGATTTAGGT
ACGGGAATGATTGTTTTAATTGTTTCGGCAATTATATTTTTTGCGGCAGGTCTTAGAATAAAATATTTTATAATACTAGG
TCTTGCTGCTCTTATTAGCCTACCTATTGCTTGGAATATGATGTATGATTATCAAAAAAAACGGGTAATGGTTTTTTTAG
ATCCCGAACATGATCCGCTCGGTGCTAGTTATAATATTATTCAGTCTAAAATCGCTATAGGTTCAGGTAGCCTATTTGGA
CGCGGTTTAAATCAAGGTAGCCAAAGCCATTTGGATTTTCTTCCCGAACATCAAACTGACTTTATCTTTGCTACCTTCGC
TGAAGAGTTCGGCTTTATAGGAGGAATGTTTTTACTAATATTATATTTTGCACTTATAACTATTTCTTTATTAATTGCCG
CAAATTGCCGAGAGATTTTTAGTAAATTAATGGTAATAGGTATTACTTCAATCTTATTTATTCACGTATTTATTAATATA
GCTATGGTTATGGGCTTGCTTCCCGTAGTAGGCGTACCGCTACCGTTTATTTCTTACGGCGGAACAATGATCGCATCCAT
GTTAATCGGCTTTGGGCTTGTGATGAATGCTCAGGTACACAGACATACCGCTTTAAACTAG

Upstream 100 bases:

>100_bases
AGGAACAAGCGCAATAAATTGAGCTTTTAAAAAGCTTTAAAGTACTGGATTCCTGCTTGCGCAGGAATGACATACAACAC
CTCTACTGAATACAAAAACA

Downstream 100 bases:

>100_bases
TGCAATTATATTGACAAAATGGATAACATAAATTAATAATAAGTTGCACTTCACTTTCTGATTTTCGTATAAAGCGAAAT
TTTCTATTGACTTTTATATA

Product: rod shape-determining protein rodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MHKNYLEQLQKLPITLILLISLICCIGFIVLYSAANSNLQPWAYKQIINFCIFLPLAIIIALIDLRIIFRLSYIFYLCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIYDLTKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVSAIIFFAAGLRIKYFIILGLAALISLPIAWNMMYDYQKKRVMVFLDPEHDPLGASYNIIQSKIAIGSGSLFG
RGLNQGSQSHLDFLPEHQTDFIFATFAEEFGFIGGMFLLILYFALITISLLIAANCREIFSKLMVIGITSILFIHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASMLIGFGLVMNAQVHRHTALN

Sequences:

>Translated_366_residues
MHKNYLEQLQKLPITLILLISLICCIGFIVLYSAANSNLQPWAYKQIINFCIFLPLAIIIALIDLRIIFRLSYIFYLCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIYDLTKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVSAIIFFAAGLRIKYFIILGLAALISLPIAWNMMYDYQKKRVMVFLDPEHDPLGASYNIIQSKIAIGSGSLFG
RGLNQGSQSHLDFLPEHQTDFIFATFAEEFGFIGGMFLLILYFALITISLLIAANCREIFSKLMVIGITSILFIHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASMLIGFGLVMNAQVHRHTALN
>Mature_366_residues
MHKNYLEQLQKLPITLILLISLICCIGFIVLYSAANSNLQPWAYKQIINFCIFLPLAIIIALIDLRIIFRLSYIFYLCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIYDLTKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVSAIIFFAAGLRIKYFIILGLAALISLPIAWNMMYDYQKKRVMVFLDPEHDPLGASYNIIQSKIAIGSGSLFG
RGLNQGSQSHLDFLPEHQTDFIFATFAEEFGFIGGMFLLILYFALITISLLIAANCREIFSKLMVIGITSILFIHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASMLIGFGLVMNAQVHRHTALN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=338, Percent_Identity=43.1952662721894, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI1786277, Length=343, Percent_Identity=31.7784256559767, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40776; Mature: 40776

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKNYLEQLQKLPITLILLISLICCIGFIVLYSAANSNLQPWAYKQIINFCIFLPLAIII
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALIDLRIIFRLSYIFYLCVLALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
LARYFHSLTIYDLTKFHKVIIPIIGVLIPAFLIIREPDLGTGMIVLIVSAIIFFAAGLRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHH
KYFIILGLAALISLPIAWNMMYDYQKKRVMVFLDPEHDPLGASYNIIQSKIAIGSGSLFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHC
RGLNQGSQSHLDFLPEHQTDFIFATFAEEFGFIGGMFLLILYFALITISLLIAANCREIF
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLMVIGITSILFIHVFINIAMVMGLLPVVGVPLPFISYGGTMIASMLIGFGLVMNAQVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCHHH
RHTALN
HHHCCC
>Mature Secondary Structure
MHKNYLEQLQKLPITLILLISLICCIGFIVLYSAANSNLQPWAYKQIINFCIFLPLAIII
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALIDLRIIFRLSYIFYLCVLALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
LARYFHSLTIYDLTKFHKVIIPIIGVLIPAFLIIREPDLGTGMIVLIVSAIIFFAAGLRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHH
KYFIILGLAALISLPIAWNMMYDYQKKRVMVFLDPEHDPLGASYNIIQSKIAIGSGSLFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHC
RGLNQGSQSHLDFLPEHQTDFIFATFAEEFGFIGGMFLLILYFALITISLLIAANCREIF
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLMVIGITSILFIHVFINIAMVMGLLPVVGVPLPFISYGGTMIASMLIGFGLVMNAQVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCHHH
RHTALN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]