| Definition | Rickettsia conorii str. Malish 7, complete genome. |
|---|---|
| Accession | NC_003103 |
| Length | 1,268,755 |
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The map label for this gene is phbB [H]
Identifier: 15891977
GI number: 15891977
Start: 47153
End: 47878
Strand: Reverse
Name: phbB [H]
Synonym: RC0054
Alternate gene names: 15891977
Gene position: 47878-47153 (Counterclockwise)
Preceding gene: 15891978
Following gene: 15891976
Centisome position: 3.77
GC content: 36.23
Gene sequence:
>726_bases ATGTCAGAACTTACAATTGTAACAGGTGGTACTAGAGGAATAGGTAAAGCTACCGCTTTAGAATTAAAAAATAAGGGTCT TACGGTAGTTGCTAATTTTTTCAGCAATTACGACACTGCTAAAGAAATAGAAGAAAAATACGGTATAAAAACCAAACGCT GGAATATTGCGAATTTTGAAGAATGTAGAAAAGCAGTAAAGGAAATTGAAGAGGAGTTTAAAAAACCGGTAAGTATTCTT GTAAATAATGCCGGTATTACCAAAGATAAAATGCTACATAGAACGAGTTATCAAGATTGGAATGATGTGATGAACATTAA TCTCAATTCTTGCTTTAATATGTCCAGTAGCGTAATGGAGCAGATACGAAACCAAGATTACGGTCGTATAATAAATATCA GTTCAATTAATGCTCAAGCAAGGCAGATTGGGCAGACTAATTACTCTGCTGCTAAAGCTGGAATTATCAGCTTTACTAAG GCCCTTGCTCGTGAAACTGCTTCTAAAAATATCACCATTAACTGTATAGCTCCAGGGTATATTGCAATCAAAATGGTAGG AGCAGTACCCGAAGACGTGCTTGTTAAAATCGTTAATAGTATCCCCAAAAAAAGACTAGGACAGCCGGAAGAAATAGCTA GAGCCGTGGCATTTTTAGTTGATGAAAATGCCGGATTTATCACAGGTGAGACTATTTCTATCAACGGCGGCCATAATATG ATTTAA
Upstream 100 bases:
>100_bases AAGTTGTTAAACCGTTAACTAAATCGGTATCACAGCTTAAACTAAGTATAACCCCACCGGTTAAATTTAATAAAAGTCAA AATATAGGTATGGAGAAATA
Downstream 100 bases:
>100_bases ACAATTAACTAATAATAGATTAGAATATGAAAGAGATCGTAAACCAATTAATCTCTAAAGGAAGAGAACTTTTAAGTAAA AATGAATATAAAGAAGCACT
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 241; Mature: 240
Protein sequence:
>241_residues MSELTIVTGGTRGIGKATALELKNKGLTVVANFFSNYDTAKEIEEKYGIKTKRWNIANFEECRKAVKEIEEEFKKPVSIL VNNAGITKDKMLHRTSYQDWNDVMNINLNSCFNMSSSVMEQIRNQDYGRIINISSINAQARQIGQTNYSAAKAGIISFTK ALARETASKNITINCIAPGYIAIKMVGAVPEDVLVKIVNSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGHNM I
Sequences:
>Translated_241_residues MSELTIVTGGTRGIGKATALELKNKGLTVVANFFSNYDTAKEIEEKYGIKTKRWNIANFEECRKAVKEIEEEFKKPVSIL VNNAGITKDKMLHRTSYQDWNDVMNINLNSCFNMSSSVMEQIRNQDYGRIINISSINAQARQIGQTNYSAAKAGIISFTK ALARETASKNITINCIAPGYIAIKMVGAVPEDVLVKIVNSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGHNM I >Mature_240_residues SELTIVTGGTRGIGKATALELKNKGLTVVANFFSNYDTAKEIEEKYGIKTKRWNIANFEECRKAVKEIEEEFKKPVSILV NNAGITKDKMLHRTSYQDWNDVMNINLNSCFNMSSSVMEQIRNQDYGRIINISSINAQARQIGQTNYSAAKAGIISFTKA LARETASKNITINCIAPGYIAIKMVGAVPEDVLVKIVNSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGHNMI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=37.4501992031873, Blast_Score=165, Evalue=3e-41, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=33.469387755102, Blast_Score=126, Evalue=1e-29, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=33.0677290836653, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI4504505, Length=234, Percent_Identity=31.6239316239316, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=28.5123966942149, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI7705925, Length=235, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=25.3275109170306, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI226371731, Length=208, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=27.2357723577236, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=27.979274611399, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=29.0983606557377, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI126723750, Length=148, Percent_Identity=29.0540540540541, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7705855, Length=197, Percent_Identity=29.4416243654822, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4557649, Length=216, Percent_Identity=28.2407407407407, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI225579078, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI4503301, Length=211, Percent_Identity=27.9620853080569, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=41.9087136929461, Blast_Score=190, Evalue=7e-50, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.327868852459, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=30.2521008403361, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.4285714285714, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082160, Length=239, Percent_Identity=31.3807531380753, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=30.4526748971193, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=27.9693486590038, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=27.8688524590164, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=31.3807531380753, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=29.4871794871795, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=25.6, Blast_Score=84, Evalue=6e-18, Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=26.2357414448669, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=25.8196721311475, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=38.3399209486166, Blast_Score=163, Evalue=7e-41, Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=36.3636363636364, Blast_Score=149, Evalue=1e-36, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.0344827586207, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=34.136546184739, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.4878048780488, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=27.4809160305344, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=27.5590551181102, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=30.3191489361702, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=29.7071129707113, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=26.2948207171315, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=29.0196078431373, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=27.5862068965517, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=29.0076335877863, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=29.5275590551181, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.3076923076923, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=28.3524904214559, Blast_Score=79, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=26.7441860465116, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=24.7148288973384, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.4809160305344, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.3358778625954, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=24.904214559387, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17561272, Length=211, Percent_Identity=26.0663507109005, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203117, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203115, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=25.4826254826255, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI25152911, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17557668, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI212646214, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17508651, Length=244, Percent_Identity=25.4098360655738, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17559552, Length=193, Percent_Identity=30.0518134715026, Blast_Score=64, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17555612, Length=233, Percent_Identity=25.7510729613734, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=30.1724137931034, Blast_Score=99, Evalue=6e-22, Organism=Saccharomyces cerevisiae, GI6323882, Length=187, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=190, Percent_Identity=29.4736842105263, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322795, Length=275, Percent_Identity=26.1818181818182, Blast_Score=70, Evalue=3e-13, Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=35.8333333333333, Blast_Score=156, Evalue=1e-38, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=32.03125, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=29.718875502008, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI18859837, Length=229, Percent_Identity=31.4410480349345, Blast_Score=100, Evalue=6e-22, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.9917355371901, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=28, Blast_Score=98, Evalue=4e-21, Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=27.1966527196653, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.5546558704453, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=31.6062176165803, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=31.6062176165803, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24644337, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=28.7958115183246, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=6e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26567; Mature: 26436
Theoretical pI: Translated: 9.33; Mature: 9.33
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSELTIVTGGTRGIGKATALELKNKGLTVVANFFSNYDTAKEIEEKYGIKTKRWNIANFE CCCEEEEECCCCCCCCHHHEEECCCCCEEEEHHHCCCCHHHHHHHHHCCCCCCCCCCCHH ECRKAVKEIEEEFKKPVSILVNNAGITKDKMLHRTSYQDWNDVMNINLNSCFNMSSSVME HHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCHHHEECCHHHHHCCHHHHHH QIRNQDYGRIINISSINAQARQIGQTNYSAAKAGIISFTKALARETASKNITINCIAPGY HHHCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCE IAIKMVGAVPEDVLVKIVNSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGHNM EEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCEEEECCCCCC I C >Mature Secondary Structure SELTIVTGGTRGIGKATALELKNKGLTVVANFFSNYDTAKEIEEKYGIKTKRWNIANFE CCEEEEECCCCCCCCHHHEEECCCCCEEEEHHHCCCCHHHHHHHHHCCCCCCCCCCCHH ECRKAVKEIEEEFKKPVSILVNNAGITKDKMLHRTSYQDWNDVMNINLNSCFNMSSSVME HHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCHHHEECCHHHHHCCHHHHHH QIRNQDYGRIINISSINAQARQIGQTNYSAAKAGIISFTKALARETASKNITINCIAPGY HHHCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCE IAIKMVGAVPEDVLVKIVNSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGGHNM EEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCEEEECCCCCC I C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2546004; 3286259 [H]