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The map label for this gene is lpxD [H]

Identifier: 15891933

GI number: 15891933

Start: 8046

End: 9086

Strand: Reverse

Name: lpxD [H]

Synonym: RC0010

Alternate gene names: 15891933

Gene position: 9086-8046 (Counterclockwise)

Preceding gene: 15891936

Following gene: 15891932

Centisome position: 0.72

GC content: 35.45

Gene sequence:

>1041_bases
ATGGTAAGTAGTAATTTTTATAAAAATCTAGGGCCACGAAAACTAACAGCAATTATAGATTTTTTACACGATATTATAGC
ACCTCCTAAGATTCATGAAGATATAGCTATTCATGATATTAAAATTCTGCAGGAAGCATCACCAAATGATATTAGCTTTT
TAAGCAATCCTAAATACTCCGAATTTTTAAAAACTACCAAAGCTGCTGCTTGTATAGTGCCGAAAAATTTTACGGGAGAA
GCAAATCCAAACACTGTTTTATTACACGCCCAGAACCCATATTTTGCTTACGGCAAATTAATAGATTTTTTTTATGCTCC
TATTAAATCATACCCTGCTAAAATAATGAAATCCGCTATTGTTGCAGATTCGGCGACTATCGGAAAAAATTGTTATATAG
GTCACAATGTAGTTATTGAAGACGATGTTATTATAGGTGATAATAGTATTATAGAAGCTGGAAGTTTTATAGGTAGAGGA
GTAAATATCGGCAGAAACGCTAGAATAGAACAACATGTTTCAATAAATTATGCAATTATAGGCGACGACGTCGTAATACT
TGCAGGTGCAAAAATTGGACAGGACGGGTTTGGATTTTCTACCGAAAAAGGCGTACATCACAAAATATCTCATATAGGAA
TAGTTAAAATCGGCAATAATGTTGAAATTGGTGCAAACACTACTATTGATAGAGGATCACTTCAAGATACAATTATAAAA
GATTTATGCCGCATAGATAATTTAGTACAAATAGGGCATGGCGTCAAAATAGGTAAAGGCTCTATTATCGTAGCACAAAC
AGGTATAGCAGGAAGTAGCACGATCGGTAAATATTGTACTCTTGGAGGGCAAGTAGGAATCGCCGGACATCTAAATATAG
GCGACGGGGCACAGGTAGCGGCACAAGGCGGTGTAGCACAAAATATAGAAGCAGGTAAAATTGTCGGCGGCAGCCCTGCA
ATTCCTATTATGGATTGGCATAGACAATCTATTATTATGAAACAATTACTAAAGACCTCTAATAGCAAATTAAAAAAGTA
G

Upstream 100 bases:

>100_bases
TCTTTACTTAGCAATACCTTTTATTCCACCTGTAAATTTTGTTGCATAATAAAACTATCACTTATATACTGTCGCTAATG
ATTAATTTGCTTAAAGTTAT

Downstream 100 bases:

>100_bases
CTTGCTATTGAAAAGAGCTTTGTTGTTGCATGAATACCTGAGTCGTCATTGTGGGCAGCCATAGGCTACGGTGGCAATCC
AAAAAAATTAGCAAAAAGTG

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIHEDIAIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKNFTGE
ANPNTVLLHAQNPYFAYGKLIDFFYAPIKSYPAKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRG
VNIGRNARIEQHVSINYAIIGDDVVILAGAKIGQDGFGFSTEKGVHHKISHIGIVKIGNNVEIGANTTIDRGSLQDTIIK
DLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCTLGGQVGIAGHLNIGDGAQVAAQGGVAQNIEAGKIVGGSPA
IPIMDWHRQSIIMKQLLKTSNSKLKK

Sequences:

>Translated_346_residues
MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIHEDIAIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKNFTGE
ANPNTVLLHAQNPYFAYGKLIDFFYAPIKSYPAKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRG
VNIGRNARIEQHVSINYAIIGDDVVILAGAKIGQDGFGFSTEKGVHHKISHIGIVKIGNNVEIGANTTIDRGSLQDTIIK
DLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCTLGGQVGIAGHLNIGDGAQVAAQGGVAQNIEAGKIVGGSPA
IPIMDWHRQSIIMKQLLKTSNSKLKK
>Mature_346_residues
MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIHEDIAIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKNFTGE
ANPNTVLLHAQNPYFAYGKLIDFFYAPIKSYPAKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRG
VNIGRNARIEQHVSINYAIIGDDVVILAGAKIGQDGFGFSTEKGVHHKISHIGIVKIGNNVEIGANTTIDRGSLQDTIIK
DLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCTLGGQVGIAGHLNIGDGAQVAAQGGVAQNIEAGKIVGGSPA
IPIMDWHRQSIIMKQLLKTSNSKLKK

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=322, Percent_Identity=37.5776397515528, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36882; Mature: 36882

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIHEDIAIHDIKILQEASPNDISFLSNPKYS
CCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEHHHCCCCCCCEECCCCCHH
EFLKTTKAAACIVPKNFTGEANPNTVLLHAQNPYFAYGKLIDFFYAPIKSYPAKIMKSAI
HHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRGVNIGRNARIEQHVSINYAII
HHCCCCCCCCEEECCEEEEECCEEECCCCEECCCHHHCCCCCCCCCCCEEEEEEEEEEEE
GDDVVILAGAKIGQDGFGFSTEKGVHHKISHIGIVKIGNNVEIGANTTIDRGSLQDTIIK
CCCEEEEECCEECCCCCCCCCCCCCHHHHCEEEEEEECCEEEECCCCCCCCCCHHHHHHH
DLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCTLGGQVGIAGHLNIGDGAQVA
HHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCHHHCCCCCEEEEEEEECCCCCHHH
AQGGVAQNIEAGKIVGGSPAIPIMDWHRQSIIMKQLLKTSNSKLKK
CCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MVSSNFYKNLGPRKLTAIIDFLHDIIAPPKIHEDIAIHDIKILQEASPNDISFLSNPKYS
CCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHEEHHHCCCCCCCEECCCCCHH
EFLKTTKAAACIVPKNFTGEANPNTVLLHAQNPYFAYGKLIDFFYAPIKSYPAKIMKSAI
HHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRGVNIGRNARIEQHVSINYAII
HHCCCCCCCCEEECCEEEEECCEEECCCCEECCCHHHCCCCCCCCCCCEEEEEEEEEEEE
GDDVVILAGAKIGQDGFGFSTEKGVHHKISHIGIVKIGNNVEIGANTTIDRGSLQDTIIK
CCCEEEEECCEECCCCCCCCCCCCCHHHHCEEEEEEECCEEEECCCCCCCCCCHHHHHHH
DLCRIDNLVQIGHGVKIGKGSIIVAQTGIAGSSTIGKYCTLGGQVGIAGHLNIGDGAQVA
HHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCHHHCCCCCEEEEEEEECCCCCHHH
AQGGVAQNIEAGKIVGGSPAIPIMDWHRQSIIMKQLLKTSNSKLKK
CCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA