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The map label for this gene is lpxA [H]

Identifier: 15891931

GI number: 15891931

Start: 6611

End: 7405

Strand: Reverse

Name: lpxA [H]

Synonym: RC0008

Alternate gene names: 15891931

Gene position: 7405-6611 (Counterclockwise)

Preceding gene: 15891932

Following gene: 15891930

Centisome position: 0.58

GC content: 36.98

Gene sequence:

>795_bases
GTGTCAAATTCTAATATCCATACTACAGCTGTAATTGCAGAAGGTGCAAAGCTTGGTAAAAACGTAAAAATCGGACCGTA
TTGTATTATAGGTCCTGAAGTTGTGCTTCATGACAATGTCGAGCTAAAATCCCATGTAGTAATTGAAGGGATTACCGAAA
TCGGCGAAAATACCGTAATCTATCCTTTTGCATCAATAGGTCAACCTCCACAAATCTTAAAATATGCTAATGAGCGATCA
AGCACGATAATTGGCTCTAATAATACTATTAGAGAATATGTTACGGTACAAGCAGGAAGCCAAAGAGGCGGAATGATGAC
AAGAGTAGGAAATAATAATTTATTTATGGTCGGCGTCCATATAGGTCATGATTGTAAAATCGGCAATAATGTAGTATTTG
CTAATTATGTAAGCCTAGCAGGTCATATTGGGGTAGGTGATTATACAATAATCGGCGGACTGTCTGCCGTACATCAATAT
GCTAGAATCGGTGAATATTCGATGATCGGCGGGCTATCGCCGGTCGGAGCAGATGTAATACCGTTTGGGCTTGTAAGTAG
CAAACGTGCGGTGCTTGAGGGCTTAAATCTAATCGGTATGAATAGAAAAGGGTTTGATAAAGTAAAGTCTTTAAGTGCTT
TAAAAGCTATCGAAGAAATTTTCTCAGGTGAAGGTAATTTTGCTGAGCGTATAAAACAAGTTGCTGAGAAATATAACAAT
AATTCTATAGTAATACAAATTATCGATTTTCTTAATCAAGATAGTAATAGAGCATTTTGTCGTTTTGAGAAGTAA

Upstream 100 bases:

>100_bases
GCTAACGTATGGAAATTTTCAAGTACGGTTACGGTCGAAGGTGAAATAGCTACAGAAAGTAAGTTTACCGCAATGATTAA
AGATAAAACATAGGGACATA

Downstream 100 bases:

>100_bases
ATTTATTTAACTAGCGATATGTAACACTTTGTGTTACAATTAAATATTATAAGGAGGATAAAAATGACAAAAAGTATTAC
GACTAGTATACGCTTAGAAA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERS
STIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQY
ARIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNN
NSIVIQIIDFLNQDSNRAFCRFEK

Sequences:

>Translated_264_residues
MSNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERS
STIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQY
ARIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNN
NSIVIQIIDFLNQDSNRAFCRFEK
>Mature_263_residues
SNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERSS
TIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQYA
RIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNNN
SIVIQIIDFLNQDSNRAFCRFEK

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=257, Percent_Identity=41.6342412451362, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28513; Mature: 28382

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVI
CCCCCEEEEEEEECCHHHCCCCEECCEEEECCEEEEECCCCCCHHEEEEEHHHCCCCCEE
YPFASIGQPPQILKYANERSSTIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVH
EEEHHCCCCHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCEEEEECCCCEEEEEEE
IGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQYARIGEYSMIGGLSPVGADVI
ECCCCEECCCEEEEEEEHHHCCCCCCCEEEEHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
PFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNN
CCCHHCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NSIVIQIIDFLNQDSNRAFCRFEK
CEEEEEEEHHHCCCCCCEEEEECC
>Mature Secondary Structure 
SNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVI
CCCCEEEEEEEECCHHHCCCCEECCEEEECCEEEEECCCCCCHHEEEEEHHHCCCCCEE
YPFASIGQPPQILKYANERSSTIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVH
EEEHHCCCCHHHHHHHCCCCCEEECCCCCEEEEEEEECCCCCCCEEEEECCCCEEEEEEE
IGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQYARIGEYSMIGGLSPVGADVI
ECCCCEECCCEEEEEEEHHHCCCCCCCEEEEHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
PFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNN
CCCHHCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NSIVIQIIDFLNQDSNRAFCRFEK
CEEEEEEEHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA