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The map label for this gene is aroA [H]

Identifier: 158425555

GI number: 158425555

Start: 4493617

End: 4495032

Strand: Direct

Name: aroA [H]

Synonym: AZC_3931

Alternate gene names: 158425555

Gene position: 4493617-4495032 (Clockwise)

Preceding gene: 158425540

Following gene: 158425556

Centisome position: 83.68

GC content: 71.12

Gene sequence:

>1416_bases
ATGAACGAACAGCCGCGCCAGCGGCGCCCGCATGAGGCCCCCATGTCCCAGGTCGAGAGCTCCCCGTCCCTTTCCGCGCA
CGGCCACGGGTCCGACCCGAAGCCCGCGACGGGCCTGCCCTCTCCCGGCCTCTCCGGCAAGGTGCGCGTGCCCGGTGACA
AGTCGGTGTCCCACCGCGCCCTCATCTTCGGCGCCCTCGCCCGTGGCGAGACGCGGGTCACCGGCCTGCTCGAAGGCGAG
GACGTGCTGAACACCGCCAAGGCCTGCGCCGCGCTGGGCGCCACGGTGGAGCGCACGGGGCCCGGCCAGTGGCGGGTGGA
AGGCGTGGGCGTCGGAAACTTCAAGGCGCCGGCTGCGCCGCTCGATTTCGGCAATTCCGGCACCGGCGTGCGCCTCATGA
TGGGCGCGGTGGCCGGCAATCCCATCCAAGCGACGTTCGACGGCGACGCCAGCCTGCGCAAGCGCCCGATGAAGCGCGTG
CTGGATCCGCTGGCCGCCATGGGCGTGAAGCTGGTGGAGGAAGCCGAGGGCGGCCGCCTGCCCATGCGCCTTGAAGGCGT
CACCGACCTCAAGGCCTTCACCTATGAAACGCCGGTCCCCTCCGCGCAGGTGAAGTCCGCCGTGCTGCTGGCTGGCCTTG
CAGCCTCCGGCGAGACGGTAGTGGTCGAGCGCGAGGCCACCCGCGACCACACCGAGCGCATGCTCGCCCATTTCGGCGCC
GACGTTTCGGTCGAACCGCACGGCGCGCACGGCCGTCGCATCACGCTGAAGGGCCGCCCGGAGCTGAAGGCCGCGCCCGT
GGACGTGCCCTCCGACCCCTCCTCCGCCGCCTTCCCGCTGGTGGCGGCGGTGATCGTGCCCGGCTCCGACATCGTCATCA
CCGACGTGATGATGAACCCGCTGCGCACCGGCCTCATCACCACGCTCAAGGAAATGGGCGCCAGCATCGAGACGCTGGCC
GAGCGCACCGAGGGCGGCGAGACGGTGGCGGACCTGCGGGTGCGCTATTCGAAGCTGAAGGGCGTGGCGGTGCCGCCGGA
GCGTGCGCCGGCCATGATCGACGAATATCCCATCCTCGCCGTCGCCGCTGCCTTTGCCGAGGGCGAGACGCGGATGCAGG
GCCTTGCGGAACTGCGCGTGAAGGAAAGCGACCGCCTCGCGGCCGTGGCGGACGGGCTTGCCGCCTGCGGCGTCACCCAC
CGCATCGAGGGCGACGACCTCATCGTCACCGGCGCGGCGGACGTGGAGGGCGGTGGCCCGGTGGCCACCCACATGGACCA
TCGCATCGCCATGTCCTTCCTGGTGCTGGGCCTCGCTTCCCGCGCCGGGGTGAAGGTGGATGACGTGAGCTTCATCGCCA
CCTCCTTCCCCACCTTCATGCCCATGATAGCCGGCCTCGGCGCCATCATCGCGTGA

Upstream 100 bases:

>100_bases
GGGAGGGTGCTCCATTGGCGAAAGGGCCGTGCCCTGTCAAGGCGAAATCCGATTCGGCCGCGTGGCAGCCCCCGCCGGCC
TGTGTTAGACGGGCCGCCGG

Downstream 100 bases:

>100_bases
TGGGGCGGCCATGATCATCGCCATCGATGGCCCCGCAGCCTCCGGCAAGGGCACGCTGGGCAAGCGCATCGCCGGGCATC
TGGGCCTCGCCCATCTCGAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRALIFGALARGETRVTGLLEGE
DVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAPLDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRV
LDPLAAMGVKLVEEAEGGRLPMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGA
DVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNPLRTGLITTLKEMGASIETLA
ERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILAVAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTH
RIEGDDLIVTGAADVEGGGPVATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA

Sequences:

>Translated_471_residues
MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRALIFGALARGETRVTGLLEGE
DVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAPLDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRV
LDPLAAMGVKLVEEAEGGRLPMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGA
DVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNPLRTGLITTLKEMGASIETLA
ERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILAVAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTH
RIEGDDLIVTGAADVEGGGPVATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA
>Mature_471_residues
MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRALIFGALARGETRVTGLLEGE
DVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAPLDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRV
LDPLAAMGVKLVEEAEGGRLPMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGA
DVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNPLRTGLITTLKEMGASIETLA
ERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILAVAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTH
RIEGDDLIVTGAADVEGGGPVATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=435, Percent_Identity=28.735632183908, Blast_Score=116, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320332, Length=437, Percent_Identity=28.8329519450801, Blast_Score=113, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 49027; Mature: 49027

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRA
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHH
LIFGALARGETRVTGLLEGEDVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAP
HEEEHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
LDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRVLDPLAAMGVKLVEEAEGGRL
CCCCCCCCCCEEEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGA
CEEECCCCCCHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCC
DVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNP
CCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHH
LRTGLITTLKEMGASIETLAERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILA
HHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHH
VAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTHRIEGDDLIVTGAADVEGGGP
HHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCC
VATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA
CHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRA
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHH
LIFGALARGETRVTGLLEGEDVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAP
HEEEHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
LDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRVLDPLAAMGVKLVEEAEGGRL
CCCCCCCCCCEEEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGA
CEEECCCCCCHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCC
DVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNP
CCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHH
LRTGLITTLKEMGASIETLAERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILA
HHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHH
VAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTHRIEGDDLIVTGAADVEGGGP
HHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCC
VATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA
CHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA