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The map label for this gene is cobT [H]

Identifier: 158425533

GI number: 158425533

Start: 4465564

End: 4466598

Strand: Reverse

Name: cobT [H]

Synonym: AZC_3909

Alternate gene names: 158425533

Gene position: 4466598-4465564 (Counterclockwise)

Preceding gene: 158425534

Following gene: 158425531

Centisome position: 83.18

GC content: 71.69

Gene sequence:

>1035_bases
GTGCCCATGTCCGCTCCCACTCACACCGGCCTGCCTTTCGACGACATCCGCCAGCTCGTCTCCACCATGCCCGGCCCCGA
TGCCGCTGCGCGGGCGATGGCCGAGGCCCGGCAGTCGGACCTCCTGAAGCCGCCCGGCGCGCTGGGGCGACTGGAAGAGA
TCGCCATCCACCTCGCCACCTGGCAGGCCAAGGGCATGCCAACCGCCGACCGGCCCATGGTGGCGGTGTTCGCGGCCACT
CACGGCATCGCCGAGCGGGGTGTCTCGCCTTATCCGGGCGCGGTGACGAAGCAGATGGTCGCCGCCTTCACGGACGGAAA
GGCGGCCGTGAACCAGATCTGCGCCAGCTTTGATGCGGGCCTGCGGGTGTTCGACCTCGCCCTCGACCTGCCGACGCCGG
ACATCACCCAGGATGCGGCGCTGGACGAGCGCGCCTGCGCCGCCACCATCGCCTTCGGCATGCAGGCCATTGCCGGCGGC
GCCGACGTGCTGGCGCTGGGCGAGATGGGCATCGGCAACACCACCATCGCCGCGGCGCTCTGCCACGCCCTCTATGGCGG
CACGCCGGAGGAATGGGTGGGCGCCGGCACCGGCGCCACGGGCGACATTCTGGACCGCAAGGTGGCTGCCGTGCGCGAGG
CCATCGCCTTCCACGGCGCGGCCTTGTCCGATCCGCTGGAGATCCTGCGCCGGGTGGGTGGGCGCGAGGTGGCGGCCATG
GTTGGTGCCATCCTCGCCGCGCGGATCGAGCGCGTGCCGGTGGTCCTCGACGGCTATGTGGTGACGGCCGCCGCCGCCGT
GCTGCACGCCATGGACCCGAGCGCCCTCGACCATTGCCTTGCCGGCCACGTCTCGGCCGAGAAGGCCCATGCGCGCCTCT
TGGAAAAGCTTCGTCTCAAGCCCATCCTCGATCTCGGCATGCGGCTCGGCGAGGGCTCGGGCGCGGCGCTGGCGCTCGGC
GTCGTGAAGGCGGCGGTCGCCACCCATCGCGGCATGGGCACCTTCAGCGACGGCGGCGTCTCCAACAAGGCGTAA

Upstream 100 bases:

>100_bases
GGCGCACGATCACCCCGCCCCGGCGGAGTGACGGCACCACCCCTCTCAGAAGCGGCGCCGGTCTTCCGGCGCCGCTTTCG
TTTCAACGCCTGATCGCCGA

Downstream 100 bases:

>100_bases
CAGGCGGTCCGCCCAGATGCATCCATCTGGGCGGCAAGGCCGGACTTGAGGCTATTCCGCCGCCAGCAGGGGCGTGGGGG
TGGTTCCCTCCGCCGCCGCG

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPMSAPTHTGLPFDDIRQLVSTMPGPDAAARAMAEARQSDLLKPPGALGRLEEIAIHLATWQAKGMPTADRPMVAVFAAT
HGIAERGVSPYPGAVTKQMVAAFTDGKAAVNQICASFDAGLRVFDLALDLPTPDITQDAALDERACAATIAFGMQAIAGG
ADVLALGEMGIGNTTIAAALCHALYGGTPEEWVGAGTGATGDILDRKVAAVREAIAFHGAALSDPLEILRRVGGREVAAM
VGAILAARIERVPVVLDGYVVTAAAAVLHAMDPSALDHCLAGHVSAEKAHARLLEKLRLKPILDLGMRLGEGSGAALALG
VVKAAVATHRGMGTFSDGGVSNKA

Sequences:

>Translated_344_residues
MPMSAPTHTGLPFDDIRQLVSTMPGPDAAARAMAEARQSDLLKPPGALGRLEEIAIHLATWQAKGMPTADRPMVAVFAAT
HGIAERGVSPYPGAVTKQMVAAFTDGKAAVNQICASFDAGLRVFDLALDLPTPDITQDAALDERACAATIAFGMQAIAGG
ADVLALGEMGIGNTTIAAALCHALYGGTPEEWVGAGTGATGDILDRKVAAVREAIAFHGAALSDPLEILRRVGGREVAAM
VGAILAARIERVPVVLDGYVVTAAAAVLHAMDPSALDHCLAGHVSAEKAHARLLEKLRLKPILDLGMRLGEGSGAALALG
VVKAAVATHRGMGTFSDGGVSNKA
>Mature_343_residues
PMSAPTHTGLPFDDIRQLVSTMPGPDAAARAMAEARQSDLLKPPGALGRLEEIAIHLATWQAKGMPTADRPMVAVFAATH
GIAERGVSPYPGAVTKQMVAAFTDGKAAVNQICASFDAGLRVFDLALDLPTPDITQDAALDERACAATIAFGMQAIAGGA
DVLALGEMGIGNTTIAAALCHALYGGTPEEWVGAGTGATGDILDRKVAAVREAIAFHGAALSDPLEILRRVGGREVAAMV
GAILAARIERVPVVLDGYVVTAAAAVLHAMDPSALDHCLAGHVSAEKAHARLLEKLRLKPILDLGMRLGEGSGAALALGV
VKAAVATHRGMGTFSDGGVSNKA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=337, Percent_Identity=33.5311572700297, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35196; Mature: 35065

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSAPTHTGLPFDDIRQLVSTMPGPDAAARAMAEARQSDLLKPPGALGRLEEIAIHLAT
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WQAKGMPTADRPMVAVFAATHGIAERGVSPYPGAVTKQMVAAFTDGKAAVNQICASFDAG
HHCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
LRVFDLALDLPTPDITQDAALDERACAATIAFGMQAIAGGADVLALGEMGIGNTTIAAAL
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
CHALYGGTPEEWVGAGTGATGDILDRKVAAVREAIAFHGAALSDPLEILRRVGGREVAAM
HHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHH
VGAILAARIERVPVVLDGYVVTAAAAVLHAMDPSALDHCLAGHVSAEKAHARLLEKLRLK
HHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PILDLGMRLGEGSGAALALGVVKAAVATHRGMGTFSDGGVSNKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PMSAPTHTGLPFDDIRQLVSTMPGPDAAARAMAEARQSDLLKPPGALGRLEEIAIHLAT
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WQAKGMPTADRPMVAVFAATHGIAERGVSPYPGAVTKQMVAAFTDGKAAVNQICASFDAG
HHCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
LRVFDLALDLPTPDITQDAALDERACAATIAFGMQAIAGGADVLALGEMGIGNTTIAAAL
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
CHALYGGTPEEWVGAGTGATGDILDRKVAAVREAIAFHGAALSDPLEILRRVGGREVAAM
HHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHH
VGAILAARIERVPVVLDGYVVTAAAAVLHAMDPSALDHCLAGHVSAEKAHARLLEKLRLK
HHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PILDLGMRLGEGSGAALALGVVKAAVATHRGMGTFSDGGVSNKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA