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The map label for this gene is mtaD [H]

Identifier: 158425517

GI number: 158425517

Start: 4444916

End: 4446361

Strand: Reverse

Name: mtaD [H]

Synonym: AZC_3893

Alternate gene names: 158425517

Gene position: 4446361-4444916 (Counterclockwise)

Preceding gene: 158425518

Following gene: 158425516

Centisome position: 82.8

GC content: 70.33

Gene sequence:

>1446_bases
GTGAGCGAGCCCCGCACGCTCTCCTGTGCCCATCTGCTGGCCGACCCGCGGGGGGCGGCCGCTGGGCCGAAGCGCCTGAC
GCTTCGGGACGGACGCATCGAGGCCCTCTTGGCAGCGCAGGGGCCGGTGGACGATCTCTTCGTCATGCCGACGCCCGTCA
ACGCCCACGATCACGGCCGGCCGGTGCGGACGAGTTCCATCGGTGCCGGCGGCAAGCCGCTGGAAGCGTGGATTCCGTAT
CTGGCCCTCTTCCCGTCTGTTGATCCCTACCTTGCCGCGGCGCTCTCCCTCTCGCACAGCGCGCTGGGCGGCGCGGGCGT
GGTGATGATGCACTACACCCGCGCGCAGGGCTTCACCGATCTTCCAGGCGAGGTGCGGGAGGTGGCGCGCGCGGCCCGCG
ACGTGGGCGTGCGGGTCGGCTTCGCGATCGCGATGAAGGATCGCAACCCGCTCGTCTATGGACCGAGTGCCTCCGTCCTG
GGCGGCGTTGCTGAGCCGGCGCGCAGCCGGATCGAACGACAGTTCCTGCGTCCGTCGCTCGAGCCGAAGGCTTTCATCGA
ACTGGCCGATGCGGTGGCGGAAGCGGCGGGCGGGCCGGATTTCGATGTCCAGTACGGGCCGAACGGCCCCCAATGGTGCT
CGGATGCGCTGCTGGAAGCGGTGGCCGAGGCGTCGGCCCGCACCGGACGCCGGGTGCATATGCACCTGCTGGAAAGCCGC
TACCAGCGGGCCTGGGCGGATGAGGCCCATCCCGGCGGCATCGTCCGGCATCTCGACGCGCTCGGCCTCCTGTCTGAGCG
CCTGACGCTTGCCCATTGCGTCTGGGCACGACCTGACGAACTCGCTCTGCTGGCCGAGCGGGGCGTCACCATCGTCAGCA
ACCCGTCCTCCAATCTCCATCTGCGCTCGGGCATCGGTCCGGTGGCCCAGATGAAGGCGCGGGGTTGCCGGGTGGCCTTC
GGCGTCGATGGCCGGGCCATGGATGAGGACGACGACATGCTGCGGGAAATCCGCCTCGCGCATCTCCTGCACCTCGGCAC
CGGCTTCAAGGCGGCGGTGACACAGAACGCCATTCTGGAGATGGCGCTGGTGAACGGCCGCCGCTCCGTCCTCAACCGCG
CGGACGGCGGTCGCCTCGCGCCCGGTGAACCGGCGGACCTGCTGGTGCTGGACTGGGCCCGGCTGGAGGATGACCGGCTG
CGGGACGATCTCGATGCCGTCGAACTGGTCGTGACCCGCGCCACTGCCCGCCACATCCGAGAGCTGATCGTGGGTGGCCG
TACCATCGTGCGCGACGGTGCCATCACCGGCATCGATCTGCGGGCGGTGCGGGCCGAGCTTCTCGCCCAGATGCGTGCCG
GCATGGCCGGCATGGCGGACCTCGCCGCGGCCCTGCCATCGCTGGAGGCCGCCATGGCCGCTCATTTCGAACCCGGGTGC
TGCTGA

Upstream 100 bases:

>100_bases
CCGAAGCCTTCGAACTGCCGAAGAAGCCCGCGCCGGCCCAGGTCTTCGACCGCGCCTTCCTGCCGCCCAAGGCCGACCGC
GTGCCGCCGCAGGTGGGCCC

Downstream 100 bases:

>100_bases
CATGCCCATCGCCAAGGTCCACCGCATTGCCACCGCGAGCCCTGACGACGTGTCGGGTCTTGCCGCTGCCATCGCCACGG
GGGCCATCGCGCCTGCGGGC

Product: cytosine deaminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGRPVRTSSIGAGGKPLEAWIPY
LALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTDLPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVL
GGVAEPARSRIERQFLRPSLEPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESR
YQRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLHLRSGIGPVAQMKARGCRVAF
GVDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILEMALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRL
RDDLDAVELVVTRATARHIRELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGC
C

Sequences:

>Translated_481_residues
MSEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGRPVRTSSIGAGGKPLEAWIPY
LALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTDLPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVL
GGVAEPARSRIERQFLRPSLEPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESR
YQRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLHLRSGIGPVAQMKARGCRVAF
GVDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILEMALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRL
RDDLDAVELVVTRATARHIRELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGC
C
>Mature_480_residues
SEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGRPVRTSSIGAGGKPLEAWIPYL
ALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTDLPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVLG
GVAEPARSRIERQFLRPSLEPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESRY
QRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLHLRSGIGPVAQMKARGCRVAFG
VDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILEMALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRLR
DDLDAVELVVTRATARHIRELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGCC

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=360, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24643849, Length=235, Percent_Identity=25.9574468085106, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 51364; Mature: 51232

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGR
CCCCCCCHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCCC
PVRTSSIGAGGKPLEAWIPYLALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCC
LPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVLGGVAEPARSRIERQFLRPSL
CCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHCCCC
EPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESR
CHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YQRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLH
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCCEE
LRSGIGPVAQMKARGCRVAFGVDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILE
EECCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRLRDDLDAVELVVTRATARHIR
HHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGC
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
C
C
>Mature Secondary Structure 
SEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGR
CCCCCCHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCCC
PVRTSSIGAGGKPLEAWIPYLALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCC
LPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVLGGVAEPARSRIERQFLRPSL
CCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHCCCC
EPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESR
CHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YQRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLH
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCCCEE
LRSGIGPVAQMKARGCRVAFGVDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILE
EECCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRLRDDLDAVELVVTRATARHIR
HHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGC
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA