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The map label for this gene is ykvY [H]

Identifier: 158425400

GI number: 158425400

Start: 4330391

End: 4331572

Strand: Direct

Name: ykvY [H]

Synonym: AZC_3776

Alternate gene names: 158425400

Gene position: 4330391-4331572 (Clockwise)

Preceding gene: 158425399

Following gene: 158425401

Centisome position: 80.64

GC content: 67.01

Gene sequence:

>1182_bases
ATGACCGCATTCGGCAATCCCTCCCGCATCGAGCGGCTGCGCACCCGGATGGCGCAGGCGGGCATCGACCTCATCGTCTC
CTTCAAGCCGGAGAACAGCTTCTATCTCACCGGCTTCAACCCCATCATCTACAGCCATCCGGTCATCGCGCTGCTGCCGC
GCGAGGGAGAGGCGCAGGTGCTGCTTCACGCGCTGCGGGACGACCACGCCCGCGCCTCCAGCTTTGTGCGCGACATCCGC
CTTTACGGTGCCTGGTCCACCAAGGTGACCATGGGTCTGCACTGGCAGGCGGCGCTCCAGAGCCTCGTCACCGAGGCGGG
CTTTGCCAATGCCGTCATCGGCATCGAGGAGGACTTCCTGCCCGTGTCGCGCCACCGCGAGCTTCAGGGATTGTTTCCGG
GCGCGAGCTTCAAGGACGTCTCCGGCCTCATCATGTCGACCCGCCTCGTGAAGGATGCGGACGAGATCGAGAACTGCCGC
GCCGCCGCCCGCATCGCGGACGTGGGCATGGACGCGGCGGTTGAGGCCGTGCGCGCCGGCGGCAGCGAGCGGGACATCGC
GCTTGCCTCCATGGCCGCCATGAACCGCTTCTGGGCCGACACCTTCCCGGACAAGGAAGTGTGCGACTTCGGCAGCCTAG
AGGGCGGCGCGCAGAACGGCCTTTGGACCTGGGCGCTCGCCGGTGAGCGCATGTTCATGAACTGCGACAACCCCACCCAG
CGCCGCCCGGCGCAGGGCGAGTGCGTGAGCATCTTCATCTGGACCATCATCAACGGCATCCATGCGGAGAATGAGCGCAC
CGTCATGGTGGGCGAGGTGCCGGAGGCCAACCGCCGGGCGCTGACCTCCATCCTCGAAATCCGCGAGGAACTGTTCCCGC
TCCTGAAGCCCGGCACGCCCATCTCCGCGCTCTTCAACGGCACCAAGGCGGGGCTGGAAGCGCGCGGCTATGGCAAGTAT
CTGCCCGGCCGCATCGGCCACGGCATCGGCCTTGGCGCCCATGAGCATCCCTCTCTGGATGCGCGCACCGACATTCCGCT
GGAGCCCGGCATGATCTTCACGCTGGAGCCGAACCTGCGGATGCCCGGCATCGGCGCCACGCAGATTTCCGACACCGTCC
TCATCACGCCCGATGGCTGCGAATTCCTCACGCAGTCCGTGGGCGGGCTGATCACGGCCTGA

Upstream 100 bases:

>100_bases
CACCTTCCCCGGCCTCGCCATCCTGCTCACCGTGCTGAGCGTGAATCTCGTGGGCGACTGGCTGCGGGACTATTTCGACC
CGAGACTGAGGACCTGACGC

Downstream 100 bases:

>100_bases
TCCGCATGGCGCCGCTCCTCCAGATCCGCAACCTCACCGTGGCGTTCGACACGCCGGCGGGGGTGGTTCATGCGGTCAAT
GACGTTTCCTACGATCTGGA

Product: Xaa-Pro aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQVLLHALRDDHARASSFVRDIR
LYGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFLPVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCR
AAARIADVGMDAAVEAVRAGGSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQ
RRPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTPISALFNGTKAGLEARGYGKY
LPGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLRMPGIGATQISDTVLITPDGCEFLTQSVGGLITA

Sequences:

>Translated_393_residues
MTAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQVLLHALRDDHARASSFVRDIR
LYGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFLPVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCR
AAARIADVGMDAAVEAVRAGGSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQ
RRPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTPISALFNGTKAGLEARGYGKY
LPGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLRMPGIGATQISDTVLITPDGCEFLTQSVGGLITA
>Mature_392_residues
TAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQVLLHALRDDHARASSFVRDIRL
YGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFLPVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCRA
AARIADVGMDAAVEAVRAGGSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQR
RPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTPISALFNGTKAGLEARGYGKYL
PGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLRMPGIGATQISDTVLITPDGCEFLTQSVGGLITA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=257, Percent_Identity=22.9571984435798, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788728, Length=241, Percent_Identity=29.045643153527, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 42772; Mature: 42641

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQV
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHCCCCEEEEECCCCCHHH
LLHALRDDHARASSFVRDIRLYGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFL
HHHHHHCCHHHHHHHHHHHHHEEEECCEEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCC
PVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCRAAARIADVGMDAAVEAVRAG
CHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCC
GSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQ
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCEEEEECCCCHH
RRPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTP
CCCCCCCEEEEEHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ISALFNGTKAGLEARGYGKYLPGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLR
HHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
MPGIGATQISDTVLITPDGCEFLTQSVGGLITA
CCCCCCCCCCCEEEECCCCHHHHHHHHCCEECC
>Mature Secondary Structure 
TAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQV
CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHCCCCEEEEECCCCCHHH
LLHALRDDHARASSFVRDIRLYGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFL
HHHHHHCCHHHHHHHHHHHHHEEEECCEEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCC
PVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCRAAARIADVGMDAAVEAVRAG
CHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCC
GSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQ
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCEEEEECCCCHH
RRPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTP
CCCCCCCEEEEEHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ISALFNGTKAGLEARGYGKYLPGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLR
HHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
MPGIGATQISDTVLITPDGCEFLTQSVGGLITA
CCCCCCCCCCCEEEECCCCHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]