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The map label for this gene is asd [H]

Identifier: 158425355

GI number: 158425355

Start: 4283426

End: 4284460

Strand: Reverse

Name: asd [H]

Synonym: AZC_3731

Alternate gene names: 158425355

Gene position: 4284460-4283426 (Counterclockwise)

Preceding gene: 158425359

Following gene: 158425354

Centisome position: 79.79

GC content: 64.93

Gene sequence:

>1035_bases
ATGGGCTACAAGGTCGCCGTTGTCGGCGCCACGGGTAACGTGGGCCGGGAGATCCTCTCGATCCTCGCCGAACGGGGTTT
CCCCGCGGACGAGGTCGTTGCGCTTGCATCGCGCCGCTCGATGGGCGTTGAGGTCTCCTACGGCGACAAAACGCTCAAGG
TGAAGGATCTGGCGACCTACGACTTCTCCGACACCGACATCTGCCTGATGTCGGCGGGCGGGGCCGTGTCGAAGGAATGG
TCGCCCAAGATCGGCGCCCAGGGCTGCGTGGTCATCGACAATTCCTCGCAGTGGCGCACCGATCCCGACGTGCCGCTGAT
CGTTCCCGAAGTGAACGCGGACGCCATCGTCGGCTTCACCAAGAAGAACATCATCGCCAACCCGAACTGCTCGACCGCGC
AGCTCGTGGTGGCGCTTAAGCCGCTGCACGACGCGGCCACCATCAAGCGCGTGGTGGTCTCCACCTATCAGTCCGTCTCC
GGCGCCGGCAAGGACGCCATGGACGAGCTGTTCTCGCAGACCCGCGCGGTCTTCGTCTCCGATCCGGTCGAGGCGAAGAA
GTTCCCGAAGCGGATCGCCTTCAACCTGATCCCCCAGATCGACGTGTTCATGGAGGACGGGTTCACGAAGGAAGAGTGGA
AGATGGTGGTCGAGACCAAGAAGATCCTCGACCCCAAGATCAAGCTCACGGCCACCTGCGTCCGCGTGCCGGTTTTCATC
TCCCACTCCGAGAGCGTGAACGTGGAGTTCGAGAAGGAGCTCTCCGCCGAGGACGCCCGCAAGATCCTGCGCGAGGCCCC
GGGCATCCTCGTGGTCGATACCCGCGAGCCGGGCGGCTATGCCACCCCCCACGAGGCGGCCGGCGAGGACGCGACCTACA
TCTCGCGTCTGCGTGACGACCCGACGGTGGAGAACGGCATCGCCTTCTGGTGCGTGTCGGACAACCTGCGCAAGGGCGCG
GCGCTGAACGCGGTTCAGATCGCGGAAGTGCTGGTGAACCGCAAGCTCATCACGGCCCGCAGCAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTCCGGCGGCGGCGCCCCACATTGCAACTTCGCGCCATATTCCTTAAAAGCGCGTGTTTCCGGCGCCTTTCGCCGGCAA
GATCATTCTAGGGAACAGTC

Downstream 100 bases:

>100_bases
GCTGCTTCAACGTTAAGACATCGAACGGCCCGGCGGGACACCGCCGGGCCGTTGTACGTTGCGGCATTGATGCGGATACG
GGGCAAAGCTTAAGTCAATA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSMGVEVSYGDKTLKVKDLATYDFSDTDICLMSAGGAVSKEW
SPKIGAQGCVVIDNSSQWRTDPDVPLIVPEVNADAIVGFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVS
GAGKDAMDELFSQTRAVFVSDPVEAKKFPKRIAFNLIPQIDVFMEDGFTKEEWKMVVETKKILDPKIKLTATCVRVPVFI
SHSESVNVEFEKELSAEDARKILREAPGILVVDTREPGGYATPHEAAGEDATYISRLRDDPTVENGIAFWCVSDNLRKGA
ALNAVQIAEVLVNRKLITARSKAA

Sequences:

>Translated_344_residues
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSMGVEVSYGDKTLKVKDLATYDFSDTDICLMSAGGAVSKEW
SPKIGAQGCVVIDNSSQWRTDPDVPLIVPEVNADAIVGFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVS
GAGKDAMDELFSQTRAVFVSDPVEAKKFPKRIAFNLIPQIDVFMEDGFTKEEWKMVVETKKILDPKIKLTATCVRVPVFI
SHSESVNVEFEKELSAEDARKILREAPGILVVDTREPGGYATPHEAAGEDATYISRLRDDPTVENGIAFWCVSDNLRKGA
ALNAVQIAEVLVNRKLITARSKAA
>Mature_343_residues
GYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSMGVEVSYGDKTLKVKDLATYDFSDTDICLMSAGGAVSKEWS
PKIGAQGCVVIDNSSQWRTDPDVPLIVPEVNADAIVGFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSG
AGKDAMDELFSQTRAVFVSDPVEAKKFPKRIAFNLIPQIDVFMEDGFTKEEWKMVVETKKILDPKIKLTATCVRVPVFIS
HSESVNVEFEKELSAEDARKILREAPGILVVDTREPGGYATPHEAAGEDATYISRLRDDPTVENGIAFWCVSDNLRKGAA
LNAVQIAEVLVNRKLITARSKAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=36.9822485207101, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=27.1468144044321, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=403, Percent_Identity=29.2803970223325, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37286; Mature: 37155

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSMGVEVSYGDKTLKVKDLATY
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEE
DFSDTDICLMSAGGAVSKEWSPKIGAQGCVVIDNSSQWRTDPDVPLIVPEVNADAIVGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEE
KKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKDAMDELFSQTRAVFVS
CCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEE
DPVEAKKFPKRIAFNLIPQIDVFMEDGFTKEEWKMVVETKKILDPKIKLTATCVRVPVFI
CCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
SHSESVNVEFEKELSAEDARKILREAPGILVVDTREPGGYATPHEAAGEDATYISRLRDD
ECCCCCCEEEHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVENGIAFWCVSDNLRKGAALNAVQIAEVLVNRKLITARSKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC
>Mature Secondary Structure 
GYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSMGVEVSYGDKTLKVKDLATY
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEE
DFSDTDICLMSAGGAVSKEWSPKIGAQGCVVIDNSSQWRTDPDVPLIVPEVNADAIVGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEE
KKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKDAMDELFSQTRAVFVS
CCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEE
DPVEAKKFPKRIAFNLIPQIDVFMEDGFTKEEWKMVVETKKILDPKIKLTATCVRVPVFI
CCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
SHSESVNVEFEKELSAEDARKILREAPGILVVDTREPGGYATPHEAAGEDATYISRLRDD
ECCCCCCEEEHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVENGIAFWCVSDNLRKGAALNAVQIAEVLVNRKLITARSKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]