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The map label for this gene is sppA [C]

Identifier: 158425341

GI number: 158425341

Start: 4263478

End: 4264449

Strand: Reverse

Name: sppA [C]

Synonym: AZC_3717

Alternate gene names: 158425341

Gene position: 4264449-4263478 (Counterclockwise)

Preceding gene: 158425342

Following gene: 158425340

Centisome position: 79.42

GC content: 67.9

Gene sequence:

>972_bases
ATGTCGCTCGATGTGGATCAGATCGTGGATCGCCGTCGCTTGCGCCGCAAACTCACCTTCTGGCGGGTGGTTGGCGTTCT
CGCCGTTGTCGCGGCTGTGGCGGTCGGCTCCTATGTGGCCGTCGGCCGGACGGTCCTCGCCTCCTCGCCCCATGTGGCGC
GGGTGGTCATCGGCGGCATCATTCGCAACGACCGCGACCGGGTGAAGATGCTGGAGGAGATCGGCCGCTCCAACGCGCGG
GCGGTCATCGTGTCCATCGACAGCCCCGGCGGCACGGTGACGGGAGCGGAACAGCTCTACGACGCGCTGCGCCAGCTGGC
CGCCAAGAAGCCCGTGGTGGCCGTGGTGGAAGGCATGGCGGCCTCCGGCGGCTATATCGCCGCCATCGGCTCCGACCACA
TCGTCTCCCGCCGCAACGCCATGGTGGGCTCCATCGGCGTGATCTTCCAGTTTCCGAACGTCACCGATCTGCTCGGCAAG
ATCGGCGTGACGGTGGAAGACATCAAATCGTCTCCGCTCAAGGCGGCGCCCAACGGCTACCAGCCCACGAGCCCCGAGGC
CCGGGCGGCCATCAATTCCCTCGTGGTGGACAGCTACGGGTGGTTCAAGGGCCTCGTCTCCGAGCGGCGCAAGCTCTCCG
ACGCGCGGCTCGCCGAAGTCTCCGACGGACGCGTCTTCACCGGCCATCAGGGCCTTGCGCTCCAGCTCGTGGACGAACTG
GGCGACGAACGCACGGCGCGGGCCTGGCTGGCGCGCGAGAAGGGCGTTCCCGAGAACCTGCGGGTGCGTACCTGGAAGTC
CGAGAGCATGGGCAGCGAGTTCGGCTGGCTGCGGGGCGCGGCGGGTGCGCTCGCCAGCGCGCTCGGCTTCGACACCGTGG
CCGGCATTCTGTCGCAAGCCACGCAGGCAGCCTTTGAAAAGGCTCAGCTTGACGGACTTTTGGCCCTCTGGCAGGCTCCC
GCGCAGAATTAA

Upstream 100 bases:

>100_bases
GGAGCGGCGCCCCCGCGGCGTCGCATCCGGCGGGTGCCGCTTGCCAAGGCGGGATGCCGCAGCTTAAGTGCGGCGCTCGG
CGGGGGCAGGAGGCAGGTCA

Downstream 100 bases:

>100_bases
AGGGTAGGGTGCGGCCGTGGGCGGCGGCTAATCCTGGATCCTGCCCGGTCTGGGCGTTTCTCCGGGTCCATCCGTCTTCA
GCCGGTCGCGAGGGGAAGCA

Product: peptidase S49 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGIIRNDRDRVKMLEEIGRSNAR
AVIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMAASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGK
IGVTVEDIKSSPLKAAPNGYQPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDEL
GDERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQATQAAFEKAQLDGLLALWQAP
AQN

Sequences:

>Translated_323_residues
MSLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGIIRNDRDRVKMLEEIGRSNAR
AVIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMAASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGK
IGVTVEDIKSSPLKAAPNGYQPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDEL
GDERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQATQAAFEKAQLDGLLALWQAP
AQN
>Mature_322_residues
SLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGIIRNDRDRVKMLEEIGRSNARA
VIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMAASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGKI
GVTVEDIKSSPLKAAPNGYQPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDELG
DERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQATQAAFEKAQLDGLLALWQAPA
QN

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=190, Percent_Identity=33.1578947368421, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787527, Length=161, Percent_Identity=31.6770186335404, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34424; Mature: 34293

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IRNDRDRVKMLEEIGRSNARAVIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMA
HHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
ASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGKIGVTVEDIKSSPLKAAPNGY
CCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCC
QPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDEL
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
GDERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQA
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAAFEKAQLDGLLALWQAPAQN
HHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IRNDRDRVKMLEEIGRSNARAVIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMA
HHCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
ASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGKIGVTVEDIKSSPLKAAPNGY
CCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCC
QPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDEL
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
GDERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQA
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAAFEKAQLDGLLALWQAPAQN
HHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]