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The map label for this gene is rmlC [H]

Identifier: 158425101

GI number: 158425101

Start: 3994445

End: 3994975

Strand: Reverse

Name: rmlC [H]

Synonym: AZC_3477

Alternate gene names: 158425101

Gene position: 3994975-3994445 (Counterclockwise)

Preceding gene: 158425102

Following gene: 158425100

Centisome position: 74.4

GC content: 65.54

Gene sequence:

>531_bases
ATGAAGATCAGCCCGACGAAGATCCCCGGCGTCATGGAGGTGGAGATCACCCCGCTCACCGACGAGCGTGGCCTGTTCGC
CCGCACCTTCTGCGCCGAGACCTTCGCGGGCCATGGGCTGGCGGATCGCTACCCGCATCAGAACACATCCTACAATCCAC
GCCGGGGCACGCTGCGGGGCCTGCATCTCCAGGCCGAGCCTAGCCCCGAGGCCAAGCTCGTGCGGGCGACACGGGGGCGC
GTGTTCGACGTGGCCGTGGACCTGCGCCCATCTTCGCCCGCTTACCGCGCCTGGACGGCAGTGGAGCTCGATGCGGACCG
GCGCAATGCCCTCTACATCCCAGCCGGCTGCGCCCACGGTTTCCTGACGCTCGATGACGACAGTGAGGTCTTCTACCTCA
TGTCGGAAACCTATGTTCCCGCCCTGGCCCGCACCTATCGCTGGAATGATCCGGCCTTTGGCGTGGACTGGCCTTTTGAG
CCCAGTGTCATTTCGGCACGCGATGCCGATGCAGAGGACTACACGCCATGA

Upstream 100 bases:

>100_bases
TGCCTTGGAACATCAAGGACGAGGTGGTGGCGAGCCATGCCCACGTCCGCGACTGGGGTGGGCGCTTCGTGATTGCCGTG
CCGAGGCTGACGGTGCTGCC

Downstream 100 bases:

>100_bases
ACGCTCCCATTGATCCTGCGGCGCTGGATGCCAGCGCGCCGGCCGCTCTCGCGGAAGTGCCGGCAGAGGTCACGCTCAGC
ATCTGCGTGCCCACCTACAA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKISPTKIPGVMEVEITPLTDERGLFARTFCAETFAGHGLADRYPHQNTSYNPRRGTLRGLHLQAEPSPEAKLVRATRGR
VFDVAVDLRPSSPAYRAWTAVELDADRRNALYIPAGCAHGFLTLDDDSEVFYLMSETYVPALARTYRWNDPAFGVDWPFE
PSVISARDADAEDYTP

Sequences:

>Translated_176_residues
MKISPTKIPGVMEVEITPLTDERGLFARTFCAETFAGHGLADRYPHQNTSYNPRRGTLRGLHLQAEPSPEAKLVRATRGR
VFDVAVDLRPSSPAYRAWTAVELDADRRNALYIPAGCAHGFLTLDDDSEVFYLMSETYVPALARTYRWNDPAFGVDWPFE
PSVISARDADAEDYTP
>Mature_176_residues
MKISPTKIPGVMEVEITPLTDERGLFARTFCAETFAGHGLADRYPHQNTSYNPRRGTLRGLHLQAEPSPEAKLVRATRGR
VFDVAVDLRPSSPAYRAWTAVELDADRRNALYIPAGCAHGFLTLDDDSEVFYLMSETYVPALARTYRWNDPAFGVDWPFE
PSVISARDADAEDYTP

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=167, Percent_Identity=38.9221556886228, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550412, Length=167, Percent_Identity=34.7305389221557, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 19694; Mature: 19694

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISPTKIPGVMEVEITPLTDERGLFARTFCAETFAGHGLADRYPHQNTSYNPRRGTLRG
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
LHLQAEPSPEAKLVRATRGRVFDVAVDLRPSSPAYRAWTAVELDADRRNALYIPAGCAHG
EEEECCCCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCC
FLTLDDDSEVFYLMSETYVPALARTYRWNDPAFGVDWPFEPSVISARDADAEDYTP
EEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKISPTKIPGVMEVEITPLTDERGLFARTFCAETFAGHGLADRYPHQNTSYNPRRGTLRG
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
LHLQAEPSPEAKLVRATRGRVFDVAVDLRPSSPAYRAWTAVELDADRRNALYIPAGCAHG
EEEECCCCCCCEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCC
FLTLDDDSEVFYLMSETYVPALARTYRWNDPAFGVDWPFEPSVISARDADAEDYTP
EEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10827167 [H]