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The map label for this gene is ppx [H]

Identifier: 158424997

GI number: 158424997

Start: 3902249

End: 3903460

Strand: Reverse

Name: ppx [H]

Synonym: AZC_3373

Alternate gene names: 158424997

Gene position: 3903460-3902249 (Counterclockwise)

Preceding gene: 158424998

Following gene: 158424996

Centisome position: 72.69

GC content: 70.71

Gene sequence:

>1212_bases
ATGAGGGACGAGACGCACCGGCCCTCACCGGACAAAGCGTGCGGAGACCGCGCGCTGTCCGTTGGCGGTGAGCCGGAAAG
CGGCTGCCCCGATCTCGGGCCGTCCATCGCGGCGCGGGACGAGGTTGACTGCGGCGGCGCCGGGAGCGCCGCCCCTTGCG
CGGAACCCGTGCCCATGGGCACGCGGTTCGGCTATCCCGGCAGCGACAACCTCTATGCCGCGCTGGACCTTGGCACCAAC
AACTGCCGTTTGCTTGTGGCCAGGCCCACGGCCCGCAACTTCCGCGTGGTCGATGCCTTCTCGCGCATCGTCCGCCTCGG
CGAGGGGCTTGGCGCCAGCGGACGGCTGAGCGCGGCGGCCATGGGTCGTGCGGTGGGTGCGCTCGAGGTCTGCGCAGGCA
AGATCCAGGCACGGGGCGTGAAGCGCATGCGCGTCATTGCCACCGAAGCCTGCCGTGCTGCGGCGAATGGCGATGAGTTC
TGCTCGGTGGTGGAAGACCGCACCGGCCTCGTGCTGGAAGTGGTCGACCGCCGCACCGAGGCGGGCCTCGCTGCCGCCGG
CTGCGCGCCCCTCGTCGATCCCAATTGCGACGGCGCCATCCTGTTCGACATCGGCGGCGGCTCCACGGAAGTGGTGTGGC
TCGGCCGCCGGGCGGCGGGCGACGATGGTCCGCCGCGTGCCCGCATCCGCTCCTGGGCCTCGCTGCCGGTGGGCGTCGTG
TCGCTCGCCGAGCGGCACGGCGGGGTGAAGGTGTCCTGCGATCTCTTCCACCGCATGGTGGCCGAAGTGGTGGATATGCT
GGAAGGCGTGCGCCAGAGCTGGGGCCTGCGACAGCCGGGCCGGATGCATCTGCTCGGCACCTCCGGCACCGTGACCACCG
TCGCCGGCATCCACCTCGGCCTCGACCGCTACGACCGCACCCGTGTGGACGGTGCCTGGCTTTATGCGGACGACATCTGC
GAGGTGGTGGACCGCCTCATGGGGATGTCGTTCGAGGAGCGGGTGTCCAATCCCTGCATCGGCGCCCAGCGGGCGGACCT
CGTTCTGGCCGGCTGCGCCATCATGGAGGCGGTCCGCGAGACTTTCCCCGCCGAGCGCCTGCGCGTGGCCGACCGTGGCC
TGCGCGAAGGCATGCTGGTGCAGCTCATGCGCGCCGATGGTGTATGGAAGCGGCATCGCGCGCAGCCCAGCTATTCGGAG
TCCTGTACTTGA

Upstream 100 bases:

>100_bases
CCGGATTGCACGTCCCTTTTCCGGTGTTACACTCCCCTTAACTGATATCGAAGGCGGGTGAGCATGCGGCAGGTCTGCAG
CTCCCTGCGAGGGGATTGAG

Downstream 100 bases:

>100_bases
GTTCCTCCCCCCGCAGTCCCGACGCACGTCCCCTCAAGGTGCGCGTGAAGTCGGCACGCACCCGCTCGTCCTCGTCCCAG
AAGTGGCTCCAGCGCCAGCT

Product: exopolyphosphatase

Products: NA

Alternate protein names: Metaphosphatase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MRDETHRPSPDKACGDRALSVGGEPESGCPDLGPSIAARDEVDCGGAGSAAPCAEPVPMGTRFGYPGSDNLYAALDLGTN
NCRLLVARPTARNFRVVDAFSRIVRLGEGLGASGRLSAAAMGRAVGALEVCAGKIQARGVKRMRVIATEACRAAANGDEF
CSVVEDRTGLVLEVVDRRTEAGLAAAGCAPLVDPNCDGAILFDIGGGSTEVVWLGRRAAGDDGPPRARIRSWASLPVGVV
SLAERHGGVKVSCDLFHRMVAEVVDMLEGVRQSWGLRQPGRMHLLGTSGTVTTVAGIHLGLDRYDRTRVDGAWLYADDIC
EVVDRLMGMSFEERVSNPCIGAQRADLVLAGCAIMEAVRETFPAERLRVADRGLREGMLVQLMRADGVWKRHRAQPSYSE
SCT

Sequences:

>Translated_403_residues
MRDETHRPSPDKACGDRALSVGGEPESGCPDLGPSIAARDEVDCGGAGSAAPCAEPVPMGTRFGYPGSDNLYAALDLGTN
NCRLLVARPTARNFRVVDAFSRIVRLGEGLGASGRLSAAAMGRAVGALEVCAGKIQARGVKRMRVIATEACRAAANGDEF
CSVVEDRTGLVLEVVDRRTEAGLAAAGCAPLVDPNCDGAILFDIGGGSTEVVWLGRRAAGDDGPPRARIRSWASLPVGVV
SLAERHGGVKVSCDLFHRMVAEVVDMLEGVRQSWGLRQPGRMHLLGTSGTVTTVAGIHLGLDRYDRTRVDGAWLYADDIC
EVVDRLMGMSFEERVSNPCIGAQRADLVLAGCAIMEAVRETFPAERLRVADRGLREGMLVQLMRADGVWKRHRAQPSYSE
SCT
>Mature_403_residues
MRDETHRPSPDKACGDRALSVGGEPESGCPDLGPSIAARDEVDCGGAGSAAPCAEPVPMGTRFGYPGSDNLYAALDLGTN
NCRLLVARPTARNFRVVDAFSRIVRLGEGLGASGRLSAAAMGRAVGALEVCAGKIQARGVKRMRVIATEACRAAANGDEF
CSVVEDRTGLVLEVVDRRTEAGLAAAGCAPLVDPNCDGAILFDIGGGSTEVVWLGRRAAGDDGPPRARIRSWASLPVGVV
SLAERHGGVKVSCDLFHRMVAEVVDMLEGVRQSWGLRQPGRMHLLGTSGTVTTVAGIHLGLDRYDRTRVDGAWLYADDIC
EVVDRLMGMSFEERVSNPCIGAQRADLVLAGCAIMEAVRETFPAERLRVADRGLREGMLVQLMRADGVWKRHRAQPSYSE
SCT

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=313, Percent_Identity=25.5591054313099, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI48994966, Length=314, Percent_Identity=27.0700636942675, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 42817; Mature: 42817

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDETHRPSPDKACGDRALSVGGEPESGCPDLGPSIAARDEVDCGGAGSAAPCAEPVPMG
CCCCCCCCCCCHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRFGYPGSDNLYAALDLGTNNCRLLVARPTARNFRVVDAFSRIVRLGEGLGASGRLSAAA
CCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
MGRAVGALEVCAGKIQARGVKRMRVIATEACRAAANGDEFCSVVEDRTGLVLEVVDRRTE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHH
AGLAAAGCAPLVDPNCDGAILFDIGGGSTEVVWLGRRAAGDDGPPRARIRSWASLPVGVV
CCCHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHH
SLAERHGGVKVSCDLFHRMVAEVVDMLEGVRQSWGLRQPGRMHLLGTSGTVTTVAGIHLG
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHC
LDRYDRTRVDGAWLYADDICEVVDRLMGMSFEERVSNPCIGAQRADLVLAGCAIMEAVRE
CCHHCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
TFPAERLRVADRGLREGMLVQLMRADGVWKRHRAQPSYSESCT
HCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRDETHRPSPDKACGDRALSVGGEPESGCPDLGPSIAARDEVDCGGAGSAAPCAEPVPMG
CCCCCCCCCCCHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRFGYPGSDNLYAALDLGTNNCRLLVARPTARNFRVVDAFSRIVRLGEGLGASGRLSAAA
CCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
MGRAVGALEVCAGKIQARGVKRMRVIATEACRAAANGDEFCSVVEDRTGLVLEVVDRRTE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHH
AGLAAAGCAPLVDPNCDGAILFDIGGGSTEVVWLGRRAAGDDGPPRARIRSWASLPVGVV
CCCHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHH
SLAERHGGVKVSCDLFHRMVAEVVDMLEGVRQSWGLRQPGRMHLLGTSGTVTTVAGIHLG
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHC
LDRYDRTRVDGAWLYADDICEVVDRLMGMSFEERVSNPCIGAQRADLVLAGCAIMEAVRE
CCHHCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
TFPAERLRVADRGLREGMLVQLMRADGVWKRHRAQPSYSESCT
HCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]