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The map label for this gene is lysR [H]

Identifier: 158424981

GI number: 158424981

Start: 3886094

End: 3887011

Strand: Reverse

Name: lysR [H]

Synonym: AZC_3357

Alternate gene names: 158424981

Gene position: 3887011-3886094 (Counterclockwise)

Preceding gene: 158424986

Following gene: 158424980

Centisome position: 72.39

GC content: 68.41

Gene sequence:

>918_bases
GTGCGCATCGATTTCCTGGGCCTGCAGGCCTTCATCGCCATCGCGGAGCGCGGCTCCTTCCTGCGTGCGGCGGCCCATCT
CAACCTTTCGCAGACGGCGCTGTCCCACCGCATGAAGAAGCTGGAGGACGACCTTGGCGTGCGCCTTCTCATCCGCTCCA
CCCGCGTGGTGACGCTGACACCCGATGGCGAGGCGCTGTTGCCCAAAGCCAAGCAGGCGCTGGCGGGGCTGGCGGCGGAA
GTGGAGGCGCTGCGCGAGAAGGCGCTGGGGCAGGAGACGCGGGTGGCGCTCGGCTGCCTGCCCACCATCGCCACGAGTCA
TCTGCCTCACGTGCTCCTCGATTTCGAGGCGGCCCATCCGGGCGTGGCGGTGAAGATCTATGACAATTCGGCCTCCGAGA
TCGCGGGGCTCGTGCGGTCCGGGGCGGCGGCCTTCGGCATCGGCATCGTGACGGCGGCCATGTGGGACCTCGAGATGACG
CCGCTGCGGAAGGAACCTTTCCTGCTGCTGTGCCCGCAGAGCCATGCCTTCGCCGACAAGCGCGCCGTTTCCTGGGGCGA
GCTGGAGGGCGTGCCGCTCATCCGCATCAGCCCGCAGGCGGGCAACCGCGCGCTCATCGATGACGCGCTGGGCAGCCGTC
GCGAGGCGCTGAACTGGCGCTATGAGGTGCAGCATGTCCAGACGGCAGTGAGCATGGTGCAGGCGGGCATCGGCCTCACC
ATCGTCCCCAAGTTTGCCATGGAGCGCTCCGCCATCCCGGGCCTGCGGCTTGTGACGTTGCGTAATCCGTCGATCACCCG
CACGCTGGTGGTCTTCACAAAGCGCGGCGTGCCGCTTTCACCCGTGGCGCGCGATCTGCTCGAGCTTGTACGCGCGCGGA
TTGCAGGGCGCCGCAGTGCGCCGGTTGCCGCACCATAG

Upstream 100 bases:

>100_bases
TCCCGCGGGAAAGAGGGCGTGCCCTGTCGCGTGTCGGCCCCAAGGGGCAACTGAGCGGCCGGGCGCGCAAGGCTCGTCCG
CTGCGAAACAAGAGGGCATC

Downstream 100 bases:

>100_bases
AAGATGCAGAAAATTCACGAATAGCCGAAAACTTGTCATTTGCTTCATCCTCCTGTTCTGGCGAAGGTCGCTGCCAAGAG
CGCGATCACGCGTCACTGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRIDFLGLQAFIAIAERGSFLRAAAHLNLSQTALSHRMKKLEDDLGVRLLIRSTRVVTLTPDGEALLPKAKQALAGLAAE
VEALREKALGQETRVALGCLPTIATSHLPHVLLDFEAAHPGVAVKIYDNSASEIAGLVRSGAAAFGIGIVTAAMWDLEMT
PLRKEPFLLLCPQSHAFADKRAVSWGELEGVPLIRISPQAGNRALIDDALGSRREALNWRYEVQHVQTAVSMVQAGIGLT
IVPKFAMERSAIPGLRLVTLRNPSITRTLVVFTKRGVPLSPVARDLLELVRARIAGRRSAPVAAP

Sequences:

>Translated_305_residues
MRIDFLGLQAFIAIAERGSFLRAAAHLNLSQTALSHRMKKLEDDLGVRLLIRSTRVVTLTPDGEALLPKAKQALAGLAAE
VEALREKALGQETRVALGCLPTIATSHLPHVLLDFEAAHPGVAVKIYDNSASEIAGLVRSGAAAFGIGIVTAAMWDLEMT
PLRKEPFLLLCPQSHAFADKRAVSWGELEGVPLIRISPQAGNRALIDDALGSRREALNWRYEVQHVQTAVSMVQAGIGLT
IVPKFAMERSAIPGLRLVTLRNPSITRTLVVFTKRGVPLSPVARDLLELVRARIAGRRSAPVAAP
>Mature_305_residues
MRIDFLGLQAFIAIAERGSFLRAAAHLNLSQTALSHRMKKLEDDLGVRLLIRSTRVVTLTPDGEALLPKAKQALAGLAAE
VEALREKALGQETRVALGCLPTIATSHLPHVLLDFEAAHPGVAVKIYDNSASEIAGLVRSGAAAFGIGIVTAAMWDLEMT
PLRKEPFLLLCPQSHAFADKRAVSWGELEGVPLIRISPQAGNRALIDDALGSRREALNWRYEVQHVQTAVSMVQAGIGLT
IVPKFAMERSAIPGLRLVTLRNPSITRTLVVFTKRGVPLSPVARDLLELVRARIAGRRSAPVAAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=290, Percent_Identity=33.7931034482759, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1788748, Length=311, Percent_Identity=32.7974276527331, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=29.0969899665552, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=27.891156462585, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=26.3888888888889, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=29.7752808988764, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790208, Length=262, Percent_Identity=29.3893129770992, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787530, Length=272, Percent_Identity=26.4705882352941, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787806, Length=256, Percent_Identity=24.609375, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789506, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789204, Length=253, Percent_Identity=23.7154150197628, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081904, Length=169, Percent_Identity=33.7278106508876, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=25.6, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786713, Length=90, Percent_Identity=42.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=119, Percent_Identity=34.453781512605, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=120, Percent_Identity=35, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788706, Length=134, Percent_Identity=31.3432835820896, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=278, Percent_Identity=27.3381294964029, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=24.0816326530612, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787589, Length=165, Percent_Identity=28.4848484848485, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32894; Mature: 32894

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDFLGLQAFIAIAERGSFLRAAAHLNLSQTALSHRMKKLEDDLGVRLLIRSTRVVTLT
CEEEHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEC
PDGEALLPKAKQALAGLAAEVEALREKALGQETRVALGCLPTIATSHLPHVLLDFEAAHP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
GVAVKIYDNSASEIAGLVRSGAAAFGIGIVTAAMWDLEMTPLRKEPFLLLCPQSHAFADK
CEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHH
RAVSWGELEGVPLIRISPQAGNRALIDDALGSRREALNWRYEVQHVQTAVSMVQAGIGLT
HCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHCCCEE
IVPKFAMERSAIPGLRLVTLRNPSITRTLVVFTKRGVPLSPVARDLLELVRARIAGRRSA
EEEHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
PVAAP
CCCCC
>Mature Secondary Structure
MRIDFLGLQAFIAIAERGSFLRAAAHLNLSQTALSHRMKKLEDDLGVRLLIRSTRVVTLT
CEEEHHHHHHHHHHHHCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEC
PDGEALLPKAKQALAGLAAEVEALREKALGQETRVALGCLPTIATSHLPHVLLDFEAAHP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
GVAVKIYDNSASEIAGLVRSGAAAFGIGIVTAAMWDLEMTPLRKEPFLLLCPQSHAFADK
CEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHH
RAVSWGELEGVPLIRISPQAGNRALIDDALGSRREALNWRYEVQHVQTAVSMVQAGIGLT
HCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHCCCEE
IVPKFAMERSAIPGLRLVTLRNPSITRTLVVFTKRGVPLSPVARDLLELVRARIAGRRSA
EEEHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
PVAAP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]