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The map label for this gene is uxaC [H]

Identifier: 158424966

GI number: 158424966

Start: 3869133

End: 3870548

Strand: Direct

Name: uxaC [H]

Synonym: AZC_3342

Alternate gene names: 158424966

Gene position: 3869133-3870548 (Clockwise)

Preceding gene: 158424965

Following gene: 158424967

Centisome position: 72.05

GC content: 67.66

Gene sequence:

>1416_bases
ATGGCGAGCCCCCTCATCCACCCCGACCGCCTGTTTCCCGCCGACCCCGCCGTGCGCGCGGTGGCGCGGCGCCTCTATGA
ACAGGTGGCGGACCTGCCCATCGTCTCGCCCCACGGCCACACCGACCCGCGCTGGTATGCGGAGAACAAGAATTTCCCGG
ATCCCGCACGCCTGTTCGTGGTGCCGGATCACTACATCTTCCGCATGCTCTACAGCCAGGGCATCCCGCTGGAGCAGCTC
GGCGTGCCCCGCCGCGACGGCGGCGAGACCGAGCAGGACGGCCGCAAGATCTGGCGCCTGTTCGCGTCCCACTATCACCT
CTTCCGCGGCACCCCGACCCGCTCGTGGCTGGACCATGCCTTCGCCACCCTCTTCGACATCGAAGAGCGGCTGAACGCGG
AGAATGCGGACCGCCTCTACGACCGCATCGCCGAGCGGCTGGAGACCGACGCCTGCAAGCCGCGCGCTTTGTTCCAGCGT
TTCAACATCGAGGCCATCGCCACCACCGAGAGCCCGCTCGACGAGCTGAAGTGGCACCAGATGATCCGCGACTCGGGCTG
GAACGGCCGCGTCGTCACCGCCTACCGTCCGGACCCGGTGGTGGACCCGGACTTCGAAGGCTTCCGCGACAATCTCACCC
GCTTCGGCGAGCTGACTGGCGAGGACACCTTCTCCTGGACCGGCTATCTGGAAGCCCACCGCAAGCGGCGCGCCTTCTTC
AAGAGCTATGGCGCCACCTCGACTGACCATGGCCACCCGAGCGCCCGCACCGCCGACCTCTCGCTCGGTGAAGCGGAGGC
TCTCTTCGAGCGCGTGGCCGGCGGCCAGGAGGTCTCGGCGCAGGATGCGGAGCTGTTCCGCGCCCAGATGCTCACCGAGA
TGGCGCGCATGTCGGTCGATGACGGGTTGGTGATGCAGATTCACCCCGGCTCGGTGCGCAACCACAATGGCGGCATCCTC
GCCCGCCACGGCCGCGACATGGGCGCCGACATCCCGAGCCGTACCGACTATGTGCACGCGCTGAAGCCGCTGCTGGACCG
CTTCGGCAACGAGAAGAACCTCACCATCATCCTGTTCACGCTGGATGAGACGAGCTACTCGCGCGAACTCGCCCCGCTCG
CCGGCCATTATCCGGTGCTGCGCCTCGGCCCGGCCTGGTGGTTCTTCGATGCGCCGGAGGGCATGAAGCGCTTCCGCGAG
CTGACCACGGAGACGGCGGGCTTCTACAACACCGTTGGCTTCAACGACGACACCCGCGCCTTCCCCTCCATTCCCGCCCG
CCACGACGTGGCCCGGCGCGTGGACTGCGCCTATCTCGCCGAACTGGTGACGACCCACCGGCTCGAGGAGGACGAGGCGC
ACGAAGTCGCCCACGATCTCGCCTACAGGCTCGCCAAGAAAGCCTACAGGCTCTGA

Upstream 100 bases:

>100_bases
GAAGCGGTCCTCGCGGTGGCGGACGCAGAGCTCAAGGCGTCGCGGCAGACGACGCGCAAAACCTCATCAAAAACGCCCCG
GGAAAGGACACGTTGAGCCC

Downstream 100 bases:

>100_bases
CCTTAGCGGGTGCAGCGCACCCGGGGGCATCCGGTCCGGTCGCATCGCACCGGTCCCGCTGGCCCGTCACCGACTTTGAA
ATCGAGCCCGATCTTCCGGC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MASPLIHPDRLFPADPAVRAVARRLYEQVADLPIVSPHGHTDPRWYAENKNFPDPARLFVVPDHYIFRMLYSQGIPLEQL
GVPRRDGGETEQDGRKIWRLFASHYHLFRGTPTRSWLDHAFATLFDIEERLNAENADRLYDRIAERLETDACKPRALFQR
FNIEAIATTESPLDELKWHQMIRDSGWNGRVVTAYRPDPVVDPDFEGFRDNLTRFGELTGEDTFSWTGYLEAHRKRRAFF
KSYGATSTDHGHPSARTADLSLGEAEALFERVAGGQEVSAQDAELFRAQMLTEMARMSVDDGLVMQIHPGSVRNHNGGIL
ARHGRDMGADIPSRTDYVHALKPLLDRFGNEKNLTIILFTLDETSYSRELAPLAGHYPVLRLGPAWWFFDAPEGMKRFRE
LTTETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAYLAELVTTHRLEEDEAHEVAHDLAYRLAKKAYRL

Sequences:

>Translated_471_residues
MASPLIHPDRLFPADPAVRAVARRLYEQVADLPIVSPHGHTDPRWYAENKNFPDPARLFVVPDHYIFRMLYSQGIPLEQL
GVPRRDGGETEQDGRKIWRLFASHYHLFRGTPTRSWLDHAFATLFDIEERLNAENADRLYDRIAERLETDACKPRALFQR
FNIEAIATTESPLDELKWHQMIRDSGWNGRVVTAYRPDPVVDPDFEGFRDNLTRFGELTGEDTFSWTGYLEAHRKRRAFF
KSYGATSTDHGHPSARTADLSLGEAEALFERVAGGQEVSAQDAELFRAQMLTEMARMSVDDGLVMQIHPGSVRNHNGGIL
ARHGRDMGADIPSRTDYVHALKPLLDRFGNEKNLTIILFTLDETSYSRELAPLAGHYPVLRLGPAWWFFDAPEGMKRFRE
LTTETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAYLAELVTTHRLEEDEAHEVAHDLAYRLAKKAYRL
>Mature_470_residues
ASPLIHPDRLFPADPAVRAVARRLYEQVADLPIVSPHGHTDPRWYAENKNFPDPARLFVVPDHYIFRMLYSQGIPLEQLG
VPRRDGGETEQDGRKIWRLFASHYHLFRGTPTRSWLDHAFATLFDIEERLNAENADRLYDRIAERLETDACKPRALFQRF
NIEAIATTESPLDELKWHQMIRDSGWNGRVVTAYRPDPVVDPDFEGFRDNLTRFGELTGEDTFSWTGYLEAHRKRRAFFK
SYGATSTDHGHPSARTADLSLGEAEALFERVAGGQEVSAQDAELFRAQMLTEMARMSVDDGLVMQIHPGSVRNHNGGILA
RHGRDMGADIPSRTDYVHALKPLLDRFGNEKNLTIILFTLDETSYSRELAPLAGHYPVLRLGPAWWFFDAPEGMKRFREL
TTETAGFYNTVGFNDDTRAFPSIPARHDVARRVDCAYLAELVTTHRLEEDEAHEVAHDLAYRLAKKAYRL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=433, Percent_Identity=26.0969976905312, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53821; Mature: 53690

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPLIHPDRLFPADPAVRAVARRLYEQVADLPIVSPHGHTDPRWYAENKNFPDPARLFV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCEEEE
VPDHYIFRMLYSQGIPLEQLGVPRRDGGETEQDGRKIWRLFASHYHLFRGTPTRSWLDHA
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FATLFDIEERLNAENADRLYDRIAERLETDACKPRALFQRFNIEAIATTESPLDELKWHQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCHHHHHHHH
MIRDSGWNGRVVTAYRPDPVVDPDFEGFRDNLTRFGELTGEDTFSWTGYLEAHRKRRAFF
HHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KSYGATSTDHGHPSARTADLSLGEAEALFERVAGGQEVSAQDAELFRAQMLTEMARMSVD
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DGLVMQIHPGSVRNHNGGILARHGRDMGADIPSRTDYVHALKPLLDRFGNEKNLTIILFT
CCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
LDETSYSRELAPLAGHYPVLRLGPAWWFFDAPEGMKRFRELTTETAGFYNTVGFNDDTRA
ECCCCCHHHHHHHCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEECCCCCCCCC
FPSIPARHDVARRVDCAYLAELVTTHRLEEDEAHEVAHDLAYRLAKKAYRL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASPLIHPDRLFPADPAVRAVARRLYEQVADLPIVSPHGHTDPRWYAENKNFPDPARLFV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCEEEE
VPDHYIFRMLYSQGIPLEQLGVPRRDGGETEQDGRKIWRLFASHYHLFRGTPTRSWLDHA
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FATLFDIEERLNAENADRLYDRIAERLETDACKPRALFQRFNIEAIATTESPLDELKWHQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCHHHHHHHH
MIRDSGWNGRVVTAYRPDPVVDPDFEGFRDNLTRFGELTGEDTFSWTGYLEAHRKRRAFF
HHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KSYGATSTDHGHPSARTADLSLGEAEALFERVAGGQEVSAQDAELFRAQMLTEMARMSVD
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DGLVMQIHPGSVRNHNGGILARHGRDMGADIPSRTDYVHALKPLLDRFGNEKNLTIILFT
CCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
LDETSYSRELAPLAGHYPVLRLGPAWWFFDAPEGMKRFRELTTETAGFYNTVGFNDDTRA
ECCCCCHHHHHHHCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEECCCCCCCCC
FPSIPARHDVARRVDCAYLAELVTTHRLEEDEAHEVAHDLAYRLAKKAYRL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]