Click here to switch to the map view.

The map label for this gene is luxR [H]

Identifier: 158424917

GI number: 158424917

Start: 3804662

End: 3805267

Strand: Direct

Name: luxR [H]

Synonym: AZC_3293

Alternate gene names: 158424917

Gene position: 3804662-3805267 (Clockwise)

Preceding gene: 158424916

Following gene: 158424918

Centisome position: 70.85

GC content: 66.67

Gene sequence:

>606_bases
ATGACCCCTGTCCGCATCTACCTCGTCGATGACGACCAGCCGGTCCGCGAGGCGCTGTGCCTACTGCTCGGCACCTATGG
CATGACGGTGGAGGCGTTCGCCGATCCCGCAACCTTCCTCGCCCATGTGGACCGGAGCCGACCCGGCTGCCTCATCCTCG
ACCTGCGCATGCCCATGATCAGCGGCCTGCAATTGCAGCAGAAGCTGGTGGAGCGTGGGATCGACTGGCCCGTCATCATG
ATCACCGGCCACGGCGACGTGAATGCCTGCCGCCGTGCCTTCAAGGCGGGCGTGCTCGACTTCCTCTCCAAGCCCTTGGA
CGAACAGGTGCTGCTGGACGCCATCGCCGCGGCAGAAAAGGCCCTTGAACAGGTGCTTGAGCGGGCGGAGGCGCAGGATC
TGCTGGGCCGCCTTACCGAGCGCGAGCGCGAGGTCCTGGACATGGTCTGCCAGGGCTGGGCGAGCAAGGAGATCGCCACC
GCGCTCAACGTCTCGGCACGGACCATCGACGCCCACCGCGCCCATATCGCGGAGAAGCTCGGCACGAGCTCCGTCGCCGA
ATTCGTGCGCCTCACGCTCGCCGATCCCGCCACGACGTCTAGGTAG

Upstream 100 bases:

>100_bases
AGCGGTGCGGCGGCAACATCTCGGCCGCGAACGCCCCTGCCGGAGGCGCGGTCTTCACCCTCACGCTTCCCGAAGCCGGC
GCCGCCCGGCAGGCCGCGCA

Downstream 100 bases:

>100_bases
CTCTACCTACATCACCCTGTGCCCTCACGGATTCAGCCCCGAAGCACCGGCCGATAGATCTGAGGCCAGAAAGCAGAGCG
CTTTCGCCCAACGATCAATC

Product: regulatory protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTPVRIYLVDDDQPVREALCLLLGTYGMTVEAFADPATFLAHVDRSRPGCLILDLRMPMISGLQLQQKLVERGIDWPVIM
ITGHGDVNACRRAFKAGVLDFLSKPLDEQVLLDAIAAAEKALEQVLERAEAQDLLGRLTEREREVLDMVCQGWASKEIAT
ALNVSARTIDAHRAHIAEKLGTSSVAEFVRLTLADPATTSR

Sequences:

>Translated_201_residues
MTPVRIYLVDDDQPVREALCLLLGTYGMTVEAFADPATFLAHVDRSRPGCLILDLRMPMISGLQLQQKLVERGIDWPVIM
ITGHGDVNACRRAFKAGVLDFLSKPLDEQVLLDAIAAAEKALEQVLERAEAQDLLGRLTEREREVLDMVCQGWASKEIAT
ALNVSARTIDAHRAHIAEKLGTSSVAEFVRLTLADPATTSR
>Mature_200_residues
TPVRIYLVDDDQPVREALCLLLGTYGMTVEAFADPATFLAHVDRSRPGCLILDLRMPMISGLQLQQKLVERGIDWPVIMI
TGHGDVNACRRAFKAGVLDFLSKPLDEQVLLDAIAAAEKALEQVLERAEAQDLLGRLTEREREVLDMVCQGWASKEIATA
LNVSARTIDAHRAHIAEKLGTSSVAEFVRLTLADPATTSR

Specific function: FixJ, when activated by fixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for fixN activation [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=31.7829457364341, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=32.8125, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788222, Length=156, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22121; Mature: 21990

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVRIYLVDDDQPVREALCLLLGTYGMTVEAFADPATFLAHVDRSRPGCLILDLRMPMI
CCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCEEEEEECCHHH
SGLQLQQKLVERGIDWPVIMITGHGDVNACRRAFKAGVLDFLSKPLDEQVLLDAIAAAEK
CCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALEQVLERAEAQDLLGRLTEREREVLDMVCQGWASKEIATALNVSARTIDAHRAHIAEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
GTSSVAEFVRLTLADPATTSR
CHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPVRIYLVDDDQPVREALCLLLGTYGMTVEAFADPATFLAHVDRSRPGCLILDLRMPMI
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCEEEEEECCHHH
SGLQLQQKLVERGIDWPVIMITGHGDVNACRRAFKAGVLDFLSKPLDEQVLLDAIAAAEK
CCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALEQVLERAEAQDLLGRLTEREREVLDMVCQGWASKEIATALNVSARTIDAHRAHIAEKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
GTSSVAEFVRLTLADPATTSR
CHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2842062; 11481432; 2663474; 1857213; 10647182 [H]