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The map label for this gene is iorA [H]

Identifier: 158424899

GI number: 158424899

Start: 3782323

End: 3782790

Strand: Reverse

Name: iorA [H]

Synonym: AZC_3275

Alternate gene names: 158424899

Gene position: 3782790-3782323 (Counterclockwise)

Preceding gene: 158424900

Following gene: 158424898

Centisome position: 70.45

GC content: 67.09

Gene sequence:

>468_bases
ATGGCCAAGCTGAACGTCAATGGTCGGGATTTCGAGATCGACGTGGAGGAGGATACGCCCCTGCTCTGGGCCCTGCGCGA
CCACGTGGGTCTCACAGGCACCAAATATGGCTGCGGCGTTGCGCAGTGCGGCGCCTGCACCGTCCATCTGGACGGGGTTG
CCACCCGCTCCTGCTCGGTGCCTGTCAGTGCCGTTGAGCCGGGACAGAAGATCGTGACCATCGAGGGGCTCGGGGCGGAG
AAGCCGCACCCGGTGCAACTGGCCTGGGCGGAGCTCGACGTCGCCCAGTGCGGCTACTGCCAGGTGGGCATGATCATGGC
CGTCTCCGCGCTGCTGGCGCAGAACCCCAGCCCGAGCGACGAGGACATCCGCTCGGAGATCACCAATATCTGCCGTTGCG
GGACCTATGGGCGCGTGCTCGCCGGCACCAAGCTCGCCGCTGCCCGCATGGCATCCAACCGGGGGTGA

Upstream 100 bases:

>100_bases
GTGACGAGCGCCGCGGACCGCGCCGCGATCACCGGCTACCTGCAGACCCTTTCGCAGCCGAAGTGAGCCTGGAACAGCAT
AACCAGACCGGGAGCAGACG

Downstream 100 bases:

>100_bases
GGAGGCCGTCATGACGCATTCTTCCCAGATCTCCTCCTCGGCCCTCAGCCGGCGCGGGTTCCTGCGCGGCGGCGCGGTGG
CGGCCGGTGCCTTCACCTTC

Product: oxidoreductase with iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSVPVSAVEPGQKIVTIEGLGAE
KPHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSDEDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG

Sequences:

>Translated_155_residues
MAKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSVPVSAVEPGQKIVTIEGLGAE
KPHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSDEDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG
>Mature_154_residues
AKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSVPVSAVEPGQKIVTIEGLGAEK
PHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSDEDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=36.5384615384615, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=37.3493975903614, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=39.7163120567376, Blast_Score=86, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17539860, Length=150, Percent_Identity=38.6666666666667, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=150, Percent_Identity=39.3333333333333, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=150, Percent_Identity=36.6666666666667, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737937, Length=164, Percent_Identity=34.7560975609756, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647195, Length=167, Percent_Identity=32.3353293413174, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=167, Percent_Identity=32.3353293413174, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=29.8136645962733, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=30.5194805194805, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16330; Mature: 16199

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSV
CEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCC
PVSAVEPGQKIVTIEGLGAEKPHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSD
CCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCCCH
EDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG
HHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHCCCC
>Mature Secondary Structure 
AKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSV
EEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCC
PVSAVEPGQKIVTIEGLGAEKPHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSD
CCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCHHHCCCCHHHHHHHHHHHHHCCCCCCH
EDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG
HHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]