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The map label for this gene is murA

Identifier: 158424775

GI number: 158424775

Start: 3604740

End: 3606029

Strand: Reverse

Name: murA

Synonym: AZC_3151

Alternate gene names: 158424775

Gene position: 3606029-3604740 (Counterclockwise)

Preceding gene: 158424776

Following gene: 158424774

Centisome position: 67.15

GC content: 69.46

Gene sequence:

>1290_bases
ATGGACAAGATTCGCATCATCGGCGGCGGCAGCCTCAACGGCACCATTCCGATCTCCGGTGCCAAGAATGCCGCCCTGCC
GCTGATGATCGCGGCGCTGCTCTCGGAAGAGAAGCTGGTGCTGGAGAATGTGCCGCGGCTCGCGGACGTGGCGCTGCTCC
AGCGCATTCTCGGCAACCACGGCGTGGACATCACGGTCAACGGCAAGCGCAACGGGGACGATCCCCACGCCGGCCAGACG
ATGGAGATCGACGCCCGCGTGATCGTCGATACCACCGCGCCCTATGATCTCGTGTCCCGGATGCGGGCCAGCTTCTGGGT
GGTCGGGCCGCTGCTGGCGCGCATGGGCGAGGCCCGCGTCTCGCTTCCCGGCGGCTGCGCCATCGGCACCCGGCCCGTGG
ACTTCCATCTCGATGCCCTGCGGGCGCTGGGCGCCGATATCGACATCGATGCCGGCTATGTGGTCGCCCGCGCGCCGCAC
GGCCTCACCGGTGCCCGCATCGTGTTCCCGAAGGTGTCGGTGGGCGCGACCCACACCGCCATCATGGCGGCGGCCCTCGC
CAAGGGCGATACGGTGATCGAGAACGCCGCCCGCGAGCCCGAGATCGTCGATCTCGCCGACTGCCTCATCAAGATGGGCG
CACGGATCGAGGGCGCGGGCACGTCCACCATCGAGATTTCCGGTGTGCCGCGCCTGCGCGGCGCGCGCCATTCGGTCCTG
CCCGACCGCATCGAGACGGGCACCTATGCCATGGCCACGGCCATGACCGGCGGCGATGTGACGCTCGCCGGCGCGCGGGC
GGACCTGCTCGAGAGTGCGCTCGATGTGCTGCGCAAGGCGGGCGCGCAGATCGACGTGAACAACGAGGGCATCCGCGTCC
GCCGCAACGGCGCGGGCATCTTCCCCGTGGAGGTCTCCACGGCGCCGCATCCGGGCTTCCCGACCGACCTTCAGGCCCAG
CTCATGGCCCTGATGACGCGGGCCCAGGGCCGCTCGCGCATCACCGAGACCATCTTCGAGAACCGCTTCATGCATGTGCA
GGAACTGGCCCGTCTCGGCGCCAATATCCATCTGGAGGGCGACACCGCCATCGTGGAGGGCTCCGACCGCCTCAAGGGCG
CCCCGGTGATGGCGACCGACCTGCGTGCCTCCGTGTCCCTCGTCATCGCCGGCCTTGCCGCCGAGGGCGAGACCATGATC
CAGCGCGTCTATCACCTCGACCGCGGCTTCGAGCGGCTGGAGGAGAAGCTCTCCCGCTGCGGCGCGCAGATCGAGCGCAT
CAGCGGCTGA

Upstream 100 bases:

>100_bases
CGGAAGGTGCGAAGAGCGGGCGAGAGGCCATGCGGCGGCGCGTGGCGCCTGGGACGGCCGTGAGCCGTCCGAGCGGGGCG
ACAAGAGGAGCAGTCGTTAC

Downstream 100 bases:

>100_bases
GCCGCGACCCGGTGGCCCGCGCCCTTGCGGCGCGGGGGCTGGCTCTCTATTTGCAGGGCACGTCGAAGGAGGGGCAATCC
CATGGACGCGCTCAAGCTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNHGVDITVNGKRNGDDPHAGQT
MEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARVSLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPH
GLTGARIVFPKVSVGATHTAIMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVL
PDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGIFPVEVSTAPHPGFPTDLQAQ
LMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEGDTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMI
QRVYHLDRGFERLEEKLSRCGAQIERISG

Sequences:

>Translated_429_residues
MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNHGVDITVNGKRNGDDPHAGQT
MEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARVSLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPH
GLTGARIVFPKVSVGATHTAIMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVL
PDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGIFPVEVSTAPHPGFPTDLQAQ
LMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEGDTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMI
QRVYHLDRGFERLEEKLSRCGAQIERISG
>Mature_429_residues
MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNHGVDITVNGKRNGDDPHAGQT
MEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARVSLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPH
GLTGARIVFPKVSVGATHTAIMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVL
PDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGIFPVEVSTAPHPGFPTDLQAQ
LMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEGDTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMI
QRVYHLDRGFERLEEKLSRCGAQIERISG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=52.6806526806527, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_AZOC5 (A8IC24)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001526067.1
- ProteinModelPortal:   A8IC24
- SMR:   A8IC24
- GeneID:   5692417
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_3151
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   ACAU438753:AZC_3151-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45420; Mature: 45420

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNH
CCCEEEEECCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCC
GVDITVNGKRNGDDPHAGQTMEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARV
CEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPHGLTGARIVFPKVSVGATHTA
ECCCCCEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHH
IMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVL
HHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCCCCCCCCCCCCC
PDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGI
CCHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEE
FPVEVSTAPHPGFPTDLQAQLMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEG
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMIQRVYHLDRGFERLEEKLSRC
CEEEEECCCCCCCCCEEEHHHHHHEEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAQIERISG
HHHHHHCCC
>Mature Secondary Structure
MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNH
CCCEEEEECCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCC
GVDITVNGKRNGDDPHAGQTMEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARV
CEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPHGLTGARIVFPKVSVGATHTA
ECCCCCEECCCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHH
IMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVL
HHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCCCCCCCCCCCCC
PDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGI
CCHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEE
FPVEVSTAPHPGFPTDLQAQLMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEG
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMIQRVYHLDRGFERLEEKLSRC
CEEEEECCCCCCCCCEEEHHHHHHEEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAQIERISG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA