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The map label for this gene is ygjG [C]

Identifier: 158424766

GI number: 158424766

Start: 3596965

End: 3598530

Strand: Reverse

Name: ygjG [C]

Synonym: AZC_3142

Alternate gene names: 158424766

Gene position: 3598530-3596965 (Counterclockwise)

Preceding gene: 158424768

Following gene: 158424765

Centisome position: 67.01

GC content: 67.94

Gene sequence:

>1566_bases
ATGCTCCTCTTTTCGGCTGTGCCGGCCGGCACGCCTCGCGGGTCAATGCCAGGGCACGCTTGCGGTTCCGCTGAAGCTGG
CCGGCAGGGGAGGCGCGCGGCTTGCCTTGAACGCGGCCGCACGGCAGGAATGGTCGGGCAGGCCCAAGCCGTTCGAGGAG
TGCCGCCCGTGTCCGTCTTCGCCAATTCCACCGCCCACTGGCGGCATCTCGACGCCGCCCACCATCTCCATCCCTTCAGC
GACACCAAGGGCCTGAATGCGGAAGGGGTGCGCGTCATCACGCGGGCGGAGGGCGTCTATATCTTCGACAGCGAGGGCAA
CCGCATTCTCGACGGCATGTCGGGCCTGTGGTGCTCGGCGGTCGGCCACGGGCGCCACGCCATCGTGGACGCCATCGCGG
ACCAATTGCGGCAGCTCGACTATTACAACACCTTCTTCAAGACCACCCATCCGGGCGCGGCGGAACTCGCCGCCGCCATT
GCGCAGGTGGCGCCCGAGGGGTTCGAGCGCGTCTTCTTTACCTCCGGCGGGTCTGAGGCGGTGGACACCGTCATCCGCAT
GGTGCGGCACTATTGGGCGGCCGTGGGCAAGCCGGGCAAGCACATCTTCATCGCGCGGAAGAATGCCTATCACGGCTCCA
CCATCGGTGGCGCGTCGCTCGGCGGCATGGCGCCCATGCATGCGCAGGGCGGCCTGCCCATTCCCGGCATCGTCCATGTG
CAGCAGCCTTACTGGTGGGGCGAGGGCGGGAACATGTCGCCCGAGGAATTCGGCCTTTTTGCCGCGCAGGAGGTGGCCCG
CGCCATCGATGAGGCGGGGCCGGAGAATGTCGCGGCCTTCATCGGCGAGCCCATCCAGGGCGCCGGCGGCGTCATCATCC
CGCCCTCCACCTATTGGCCGGAAGTGCAGAAGATTTGCCGCGAGCGCGACGTGCTGCTGGTCTCCGATGAGGTGATCTGC
GGCTTCGGCCGCACGGGCGAATGGTTCGGCTGCCAGCATATGGGCGTGCAACCGGACCTCATCACCTTCGCCAAGGGCGT
CACCTCCGGCTATTTCCCGCTGGGCGGCGTCATCGTGGGCGAACGGGTGGCCGAAGGGCTCATCGAGCAGGGCGGTGAAT
TCCACCACGGCTATACCTATTCCGGCCACCCCGGCGGCTGCGCGGCGGCGCTGGCGACGCTCAAGATCATGCATGAGGAA
GACCTCGTCGCCCGCGTGAAGTGCGAGATCGGGCCCTATCTCCAGGAGCGCTGGCTGCCATTGGCCAACCATCCGCTGGT
GGGCGAGGCGCGCATGGTCGGGCTCATCGGGGCGCTGGAACTGACGCCTCACAAGGAGACGCGTGCGAAGTTCCCCGGAG
AAGTCGGCACCGTCGGCCTCATCGCGCGCGACATTTCCTTCCGCGAGGGGCTGGTGATGCGCGCGGTGCGCGACAGCCTG
ATCCTCGCCCCGCCCTTCACCCTCAGCGAGGAGGAAGCGGACGACCTGATCGCGACCGTCGGTCGTGTGCTCGACCAGAC
GCTCGCGGTGGTGCGCGACCGCGGTCTCATGGGGCCGCCCCTCTGA

Upstream 100 bases:

>100_bases
GGTCTGAGGCCCGGCGGCAAACCGAAGCACCAACCCTGACCGTCCGGAGCCGGCACGCCCGCGCGCCAGTCCTCCAGCAG
CACGTCGTAAGCCTGCATGG

Downstream 100 bases:

>100_bases
GCGGACGCTTCCGGTCAACCTGACCCAGATGAGGCGCCACCGGCCCGCTGCCGCGCAGAGAGTTCGCGTCGCGGCGGGCC
GCTCTCTTCTTGCCGGCGAA

Product: aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVFANSTAHWRHLDAAHHLHPFS
DTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSAVGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAI
AQVAPEGFERVFFTSGGSEAVDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHV
QQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWPEVQKICRERDVLLVSDEVIC
GFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVGERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEE
DLVARVKCEIGPYLQERWLPLANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSL
ILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL

Sequences:

>Translated_521_residues
MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVFANSTAHWRHLDAAHHLHPFS
DTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSAVGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAI
AQVAPEGFERVFFTSGGSEAVDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHV
QQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWPEVQKICRERDVLLVSDEVIC
GFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVGERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEE
DLVARVKCEIGPYLQERWLPLANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSL
ILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL
>Mature_521_residues
MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVFANSTAHWRHLDAAHHLHPFS
DTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSAVGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAI
AQVAPEGFERVFFTSGGSEAVDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHV
QQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWPEVQKICRERDVLLVSDEVIC
GFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVGERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEE
DLVARVKCEIGPYLQERWLPLANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSL
ILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=29.9528301886792, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=29.4811320754717, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI226442709, Length=396, Percent_Identity=29.5454545454545, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=28.4722222222222, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI13994255, Length=432, Percent_Identity=29.6296296296296, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4557809, Length=484, Percent_Identity=27.4793388429752, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=31.304347826087, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI145693181, Length=409, Percent_Identity=30.5623471882641, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1786991, Length=445, Percent_Identity=30.3370786516854, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1789016, Length=421, Percent_Identity=30.166270783848, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789759, Length=360, Percent_Identity=29.1666666666667, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=28.3582089552239, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787560, Length=355, Percent_Identity=30.1408450704225, Blast_Score=122, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71992977, Length=442, Percent_Identity=28.5067873303167, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=26.1282660332542, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=26.5168539325843, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=315, Percent_Identity=28.8888888888889, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323470, Length=462, Percent_Identity=26.6233766233766, Blast_Score=159, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6324386, Length=480, Percent_Identity=26.4583333333333, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=410, Percent_Identity=24.8780487804878, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=29.2565947242206, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574759, Length=380, Percent_Identity=30.2631578947368, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI161085790, Length=380, Percent_Identity=30.2631578947368, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21357415, Length=440, Percent_Identity=26.8181818181818, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=22.4824355971897, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=22.4824355971897, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=22.4824355971897, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 55618; Mature: 55618

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVF
CEEEECCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCCHHHH
ANSTAHWRHLDAAHHLHPFSDTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSA
CCCCCHHHCCCHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEHHCCCCHHHHH
VGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAIAQVAPEGFERVFFTSGGSEA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHH
VDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
QQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWP
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECCCCCCH
EVQKICRERDVLLVSDEVICGFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVG
HHHHHHHHCCEEEEECCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHH
ERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEEDLVARVKCEIGPYLQERWLP
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHEEEEHHCCHHHHHHCCC
LANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSL
CCCCCCCCCHHHHHHHEEEECCCCHHHHHCCCCCCCCHHHEEECCHHHHHHHHHHHHHCE
ILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVF
CEEEECCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCCHHHH
ANSTAHWRHLDAAHHLHPFSDTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSA
CCCCCHHHCCCHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEHHCCCCHHHHH
VGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAIAQVAPEGFERVFFTSGGSEA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHH
VDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
QQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWP
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECCCCCCH
EVQKICRERDVLLVSDEVICGFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVG
HHHHHHHHCCEEEEECCEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHH
ERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEEDLVARVKCEIGPYLQERWLP
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHEEEEHHCCHHHHHHCCC
LANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSL
CCCCCCCCCHHHHHHHEEEECCCCHHHHHCCCCCCCCHHHEEECCHHHHHHHHHHHHHCE
ILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]